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Protein

Heat shock protein Hsp-16.1/Hsp-16.11

Gene

hsp-16.1

more
Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. unfolded protein binding Source: WormBase

GO - Biological processi

  1. endoplasmic reticulum unfolded protein response Source: WormBase
  2. response to heat Source: WormBase
Complete GO annotation...

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein Hsp-16.1/Hsp-16.11
Gene namesi
Name:hsp-16.1
Synonyms:hsp16-1b
ORF Names:T27E4.8
AND
Name:hsp-16.11
Synonyms:hsp16-1a
ORF Names:T27E4.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiT27E4.2; CE14249; WBGene00002017; hsp-16.11.
T27E4.8; CE14249; WBGene00002015; hsp-16.1.

Subcellular locationi

GO - Cellular componenti

  1. Golgi medial cisterna Source: WormBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Heat shock protein Hsp-16.1/Hsp-16.11PRO_0000125958Add
BLAST

Proteomic databases

PaxDbiP34696.
PRIDEiP34696.

Expressioni

Gene expression databases

ExpressionAtlasiP34696. baseline.

Interactioni

Protein-protein interaction databases

BioGridi44327. 3 interactions.
IntActiP34696. 1 interaction.
STRINGi6239.T27E4.8.

Structurei

3D structure databases

ProteinModelPortaliP34696.
SMRiP34696. Positions 41-123.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG245281.
GeneTreeiENSGT00760000119238.
InParanoidiP34696.
OMAiKETIQGR.
OrthoDBiEOG70W3HB.
PhylomeDBiP34696.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR001436. Alpha-crystallin/HSP.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
PIRSFiPIRSF036514. Sm_HSP_B1. 1 hit.
PRINTSiPR00299. ACRYSTALLIN.
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P34696-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLYHYFRPA QRSVFGDLMR DMAQMERQFT PVCRGSPSES SEIVNNDQKF
60 70 80 90 100
AINLNVSQFK PEDLKINLDG HTLSIQGEQE LKTEHGYSKK SFSRVILLPE
110 120 130 140
DVDVGAVASN LSEDGKLSIE APKKEAIQGR SIPIQQAPVE QKTSE
Length:145
Mass (Da):16,253
Last modified:February 1, 1994 - v1
Checksum:i06C36A1F06D15A11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K03273 Genomic DNA. Translation: AAA28068.1.
FO080670 Genomic DNA. Translation: CCD65662.1.
FO080670 Genomic DNA. Translation: CCD65668.1.
PIRiB24289.
RefSeqiNP_505354.1. NM_072953.3.
NP_505357.1. NM_072956.3.
UniGeneiCel.3204.
Cel.34471.

Genome annotation databases

EnsemblMetazoaiT27E4.2; T27E4.2; WBGene00002017.
T27E4.8; T27E4.8; WBGene00002015.
GeneIDi179286.
179289.
KEGGicel:CELE_T27E4.2.
cel:CELE_T27E4.8.
UCSCiT27E4.8. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K03273 Genomic DNA. Translation: AAA28068.1.
FO080670 Genomic DNA. Translation: CCD65662.1.
FO080670 Genomic DNA. Translation: CCD65668.1.
PIRiB24289.
RefSeqiNP_505354.1. NM_072953.3.
NP_505357.1. NM_072956.3.
UniGeneiCel.3204.
Cel.34471.

3D structure databases

ProteinModelPortaliP34696.
SMRiP34696. Positions 41-123.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi44327. 3 interactions.
IntActiP34696. 1 interaction.
STRINGi6239.T27E4.8.

Proteomic databases

PaxDbiP34696.
PRIDEiP34696.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT27E4.2; T27E4.2; WBGene00002017.
T27E4.8; T27E4.8; WBGene00002015.
GeneIDi179286.
179289.
KEGGicel:CELE_T27E4.2.
cel:CELE_T27E4.8.
UCSCiT27E4.8. c. elegans.

Organism-specific databases

CTDi179286.
179289.
WormBaseiT27E4.2; CE14249; WBGene00002017; hsp-16.11.
T27E4.8; CE14249; WBGene00002015; hsp-16.1.

Phylogenomic databases

eggNOGiNOG245281.
GeneTreeiENSGT00760000119238.
InParanoidiP34696.
OMAiKETIQGR.
OrthoDBiEOG70W3HB.
PhylomeDBiP34696.

Miscellaneous databases

NextBioi904728.
PROiP34696.

Gene expression databases

ExpressionAtlasiP34696. baseline.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR001436. Alpha-crystallin/HSP.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
PIRSFiPIRSF036514. Sm_HSP_B1. 1 hit.
PRINTSiPR00299. ACRYSTALLIN.
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Locus encoding a family of small heat shock genes in Caenorhabditis elegans: two genes duplicated to form a 3.8-kilobase inverted repeat."
    Russnak R.H., Candido E.P.M.
    Mol. Cell. Biol. 5:1268-1278(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (HSP-16.1 AND HSP-16.11).
    Strain: Bristol N2.
  3. "Expression of intron-containing C. elegans heat shock genes in mouse cells demonstrates divergence of 3' splice site recognition sequences between nematodes and vertebrates, and an inhibitory effect of heat shock on the mammalian splicing apparatus."
    Kay R.J., Russnak R.H., Jones D., Mathias C., Candido E.P.M.
    Nucleic Acids Res. 15:3723-3741(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 41-63.

Entry informationi

Entry nameiHSP11_CAEEL
AccessioniPrimary (citable) accession number: P34696
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: April 29, 2015
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.