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P34504

- YMV2_CAEEL

UniProt

P34504 - YMV2_CAEEL

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Protein

Uncharacterized protein K04H4.2

Gene

K04H4.2

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. chitin binding Source: UniProtKB-KW

GO - Biological processi

  1. chitin metabolic process Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Chitin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein K04H4.2
Gene namesi
ORF Names:K04H4.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome III

Organism-specific databases

WormBaseiK04H4.2a; CE32463; WBGene00010573.
K04H4.2b; CE36653; WBGene00010573.
K04H4.2c; CE47897; WBGene00010573.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence AnalysisAdd
BLAST
Chaini18 – 14631446Uncharacterized protein K04H4.2PRO_0000014291Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi141 ↔ 154By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP34504.
PRIDEiP34504.

Interactioni

Protein-protein interaction databases

BioGridi41513. 5 interactions.
IntActiP34504. 11 interactions.
MINTiMINT-116825.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini94 – 16471Chitin-binding type-2Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi177 – 26286Cys-richAdd
BLAST
Compositional biasi353 – 41159Cys-richAdd
BLAST
Compositional biasi879 – 1162284Cys-richAdd
BLAST

Sequence similaritiesi

Contains 1 chitin-binding type-2 domain.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG12793.
GeneTreeiENSGT00730000113271.
HOGENOMiHOG000019167.
InParanoidiP34504.
OMAiCTIDESC.

Family and domain databases

InterProiIPR007026. CC_domain.
IPR002557. Chitin-bd_dom.
IPR006150. Cys_repeat_1.
[Graphical view]
PfamiPF04942. CC. 3 hits.
[Graphical view]
SMARTiSM00494. ChtBD2. 1 hit.
SM00289. WR1. 19 hits.
[Graphical view]
SUPFAMiSSF57625. SSF57625. 1 hit.

Sequences (3)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform c (identifier: P34504-3) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLRNLILITL LVASGHGQTP VIGGTCKLGT ADVQIGGKQT QFFLKCETTA
60 70 80 90 100
DSAEGEGVWV VKSRAAAAPS SVPSVPAENT QPQQHPKARK PASPNICEQD
110 120 130 140 150
NGARESEVCA VSATCLQAHN DFPSSYLQCD QTTLRWVRKS CQENFLFNFE
160 170 180 190 200
QQTCIVPKRM SSLSPSTSSP SNTENPCSKC PLGSACRNGN CIPLTTSNLC
210 220 230 240 250
SDGSPPNNTC TRDPYSCPKG HFCTAQKVCC PSTALQSSIG CSTVCTIDES
260 270 280 290 300
CPKGMTCQNN CCEERKLLRH PKVYRYATVE ATNTIFEVDN DIFDSAAIES
310 320 330 340 350
LPTQKPQRLD EIMAPGITPT PTRTTEPPKL RCLSSNTDEV NSLGGASSSS
360 370 380 390 400
ATCGGTNANC TSDEDCPTTF KCYQGCCKLA VCPRSLTAVK FTCKTQYHCR
410 420 430 440 450
ANEHCFFGGC CPKTIELAVI KSQVLTMSKD NEHTKETEKL IIGDCEVDTR
460 470 480 490 500
VKKCDIDIIC PEMSECVDGI CCKQPPKARC GNGLMALSIP VHCSLSDDCP
510 520 530 540 550
IASRCEYGKC CPFLSESADS TSDSVGETTP VIIKEEIIST ATKVWKKVDK
560 570 580 590 600
TSGVSINKNK CLSTQRCDLH TLCPPDFTCS LSGKCCKLNI HCPDGTVPET
610 620 630 640 650
SCQSASNHDH CPSSSHKCTL LNKEHFACCY SPGLVVEGSV TAEVSSECPI
660 670 680 690 700
GSVEVDPRFG TSCRYSLQCP SPYFCNQRGQ QASGLVCTFS SCSNSNPCSV
710 720 730 740 750
GTCNNGYCCS SGSNSGSAII DSDTNSTTNP SQPETTKTKN NTKKSNSSKK
760 770 780 790 800
HRKPKKKDVD PLSDPLLQND FPIGPPGYGF PEHLSNLDEV LIRAQGDGVS
810 820 830 840 850
CAGGFQSSLI CSVGSECPAG LHCDTAINLC CPLLLPLTDP KNPKKRKTKR
860 870 880 890 900
RKQKQDENEM EASANFPDSD PARFSSYSCG CMGGGSSNCV GCQNAPQIIT
910 920 930 940 950
IPQNSCPGGG YSVGGCSSGY CATGYSCIQN QCCPSYNSAP RISVYTCPSG
960 970 980 990 1000
GNAVGACMSG RCASGYTCSN NVCCPQTTTT NPFVCPDGTQ AAGGCVNGQC
1010 1020 1030 1040 1050
GTGYTCSNGL CCAGTSTTVK CLDGSDAVGA CIPSCTGDGC GGVQVSYYCG
1060 1070 1080 1090 1100
SGYTCTTGNI CCPINSCPNG GEVLGPTING LCPTGYTVQG NLCCSATCTD
1110 1120 1130 1140 1150
GSTGLPSVNG VCIDGYSLTN GVCCPASVTC TDEISIGPCT GTGFNGGCPA
1160 1170 1180 1190 1200
GYACDSNQVN CCPVVRYTDE SCQVGPAIDG LCPPGYVVVY IPNSPLITNG
1210 1220 1230 1240 1250
VNPGTCIDLQ CTTGLCLTAN QIGDCDTATD AGTCPTGYTC FTNAGICCST
1260 1270 1280 1290 1300
TTFSRLRIGN SRQMAQKPNY GRPLHSYMPP RFGGPSSSCS DGSLSSGPCM
1310 1320 1330 1340 1350
NGLCGIGLEC QNGKCCSPSS NKPAGLLQSK CPSGDTAVSG CFPNGSCGTG
1360 1370 1380 1390 1400
YECVSSLNLC CPPGQPQTFP SFPGNNNGFN INNNNRFGSL SMSPRPIGAR
1410 1420 1430 1440 1450
CQLDGECVGQ AEGLSMCHAG VCQCSPIAYT QGIACVRRKS FQMNDDPVID
1460
AANDDKSSSS VSV

Note: No experimental confirmation available.

Length:1,463
Mass (Da):153,114
Last modified:September 18, 2013 - v8
Checksum:i00A97AEFD99B3A7B
GO
Isoform b (identifier: P34504-1) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     165-165: P → R
     166-679: Missing.
     721-721: D → V
     722-882: Missing.

Note: No experimental confirmation available.

Show »
Length:788
Mass (Da):80,380
Checksum:iC0D85035108B37C1
GO
Isoform a (identifier: P34504-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     165-165: P → R
     166-679: Missing.
     721-721: D → V
     722-882: Missing.
     1281-1440: Missing.

Note: No experimental confirmation available.

Show »
Length:628
Mass (Da):64,137
Checksum:i15A4A67BF8383E9B
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei165 – 1651P → R in isoform a and isoform b. CuratedVSP_012169
Alternative sequencei166 – 679514Missing in isoform a and isoform b. CuratedVSP_012168Add
BLAST
Alternative sequencei721 – 7211D → V in isoform a and isoform b. CuratedVSP_026510
Alternative sequencei722 – 882161Missing in isoform a and isoform b. CuratedVSP_026511Add
BLAST
Alternative sequencei1281 – 1440160Missing in isoform a. CuratedVSP_002449Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z27078 Genomic DNA. Translation: CAA81587.2.
Z27078 Genomic DNA. Translation: CAA81588.3.
Z27078 Genomic DNA. Translation: CAH04706.4.
PIRiB88553.
S40992.
S40994.
RefSeqiNP_001022664.4. NM_001027493.5. [P34504-3]
NP_499058.3. NM_066657.5. [P34504-1]
NP_499059.2. NM_066658.4. [P34504-2]
UniGeneiCel.24437.

Genome annotation databases

EnsemblMetazoaiK04H4.2c.1; K04H4.2c.1; WBGene00010573. [P34504-3]
K04H4.2c.2; K04H4.2c.2; WBGene00010573. [P34504-3]
K04H4.2c.3; K04H4.2c.3; WBGene00010573. [P34504-3]
GeneIDi176315.
KEGGicel:CELE_K04H4.2.
UCSCiK04H4.2a.2. c. elegans. [P34504-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z27078 Genomic DNA. Translation: CAA81587.2 .
Z27078 Genomic DNA. Translation: CAA81588.3 .
Z27078 Genomic DNA. Translation: CAH04706.4 .
PIRi B88553.
S40992.
S40994.
RefSeqi NP_001022664.4. NM_001027493.5. [P34504-3 ]
NP_499058.3. NM_066657.5. [P34504-1 ]
NP_499059.2. NM_066658.4. [P34504-2 ]
UniGenei Cel.24437.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 41513. 5 interactions.
IntActi P34504. 11 interactions.
MINTi MINT-116825.

Proteomic databases

PaxDbi P34504.
PRIDEi P34504.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai K04H4.2c.1 ; K04H4.2c.1 ; WBGene00010573 . [P34504-3 ]
K04H4.2c.2 ; K04H4.2c.2 ; WBGene00010573 . [P34504-3 ]
K04H4.2c.3 ; K04H4.2c.3 ; WBGene00010573 . [P34504-3 ]
GeneIDi 176315.
KEGGi cel:CELE_K04H4.2.
UCSCi K04H4.2a.2. c. elegans. [P34504-1 ]

Organism-specific databases

CTDi 176315.
WormBasei K04H4.2a ; CE32463 ; WBGene00010573 .
K04H4.2b ; CE36653 ; WBGene00010573 .
K04H4.2c ; CE47897 ; WBGene00010573 .

Phylogenomic databases

eggNOGi NOG12793.
GeneTreei ENSGT00730000113271.
HOGENOMi HOG000019167.
InParanoidi P34504.
OMAi CTIDESC.

Miscellaneous databases

NextBioi 892054.

Family and domain databases

InterProi IPR007026. CC_domain.
IPR002557. Chitin-bd_dom.
IPR006150. Cys_repeat_1.
[Graphical view ]
Pfami PF04942. CC. 3 hits.
[Graphical view ]
SMARTi SM00494. ChtBD2. 1 hit.
SM00289. WR1. 19 hits.
[Graphical view ]
SUPFAMi SSF57625. SSF57625. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
    Strain: Bristol N2.

Entry informationi

Entry nameiYMV2_CAEEL
AccessioniPrimary (citable) accession number: P34504
Secondary accession number(s): P34505
, P34506, P90907, Q6BEV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: September 18, 2013
Last modified: October 1, 2014
This is version 118 of the entry and version 8 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3