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P34504

- YMV2_CAEEL

UniProt

P34504 - YMV2_CAEEL

Protein

Uncharacterized protein K04H4.2

Gene

K04H4.2

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 118 (01 Oct 2014)
      Sequence version 8 (18 Sep 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. chitin binding Source: UniProtKB-KW

    GO - Biological processi

    1. chitin metabolic process Source: InterPro

    Keywords - Ligandi

    Chitin-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein K04H4.2
    Gene namesi
    ORF Names:K04H4.2
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome III

    Organism-specific databases

    WormBaseiK04H4.2a; CE32463; WBGene00010573.
    K04H4.2b; CE36653; WBGene00010573.
    K04H4.2c; CE47897; WBGene00010573.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1717Sequence AnalysisAdd
    BLAST
    Chaini18 – 14631446Uncharacterized protein K04H4.2PRO_0000014291Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi141 ↔ 154By similarity

    Keywords - PTMi

    Disulfide bond

    Proteomic databases

    PaxDbiP34504.
    PRIDEiP34504.

    Interactioni

    Protein-protein interaction databases

    BioGridi41513. 5 interactions.
    IntActiP34504. 11 interactions.
    MINTiMINT-116825.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini94 – 16471Chitin-binding type-2Add
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi177 – 26286Cys-richAdd
    BLAST
    Compositional biasi353 – 41159Cys-richAdd
    BLAST
    Compositional biasi879 – 1162284Cys-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 chitin-binding type-2 domain.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG12793.
    GeneTreeiENSGT00730000113271.
    HOGENOMiHOG000019167.
    InParanoidiP34504.
    OMAiCTIDESC.

    Family and domain databases

    InterProiIPR007026. CC_domain.
    IPR002557. Chitin-bd_dom.
    IPR006150. Cys_repeat_1.
    [Graphical view]
    PfamiPF04942. CC. 3 hits.
    [Graphical view]
    SMARTiSM00494. ChtBD2. 1 hit.
    SM00289. WR1. 19 hits.
    [Graphical view]
    SUPFAMiSSF57625. SSF57625. 1 hit.

    Sequences (3)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform c (identifier: P34504-3) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MLRNLILITL LVASGHGQTP VIGGTCKLGT ADVQIGGKQT QFFLKCETTA     50
    DSAEGEGVWV VKSRAAAAPS SVPSVPAENT QPQQHPKARK PASPNICEQD 100
    NGARESEVCA VSATCLQAHN DFPSSYLQCD QTTLRWVRKS CQENFLFNFE 150
    QQTCIVPKRM SSLSPSTSSP SNTENPCSKC PLGSACRNGN CIPLTTSNLC 200
    SDGSPPNNTC TRDPYSCPKG HFCTAQKVCC PSTALQSSIG CSTVCTIDES 250
    CPKGMTCQNN CCEERKLLRH PKVYRYATVE ATNTIFEVDN DIFDSAAIES 300
    LPTQKPQRLD EIMAPGITPT PTRTTEPPKL RCLSSNTDEV NSLGGASSSS 350
    ATCGGTNANC TSDEDCPTTF KCYQGCCKLA VCPRSLTAVK FTCKTQYHCR 400
    ANEHCFFGGC CPKTIELAVI KSQVLTMSKD NEHTKETEKL IIGDCEVDTR 450
    VKKCDIDIIC PEMSECVDGI CCKQPPKARC GNGLMALSIP VHCSLSDDCP 500
    IASRCEYGKC CPFLSESADS TSDSVGETTP VIIKEEIIST ATKVWKKVDK 550
    TSGVSINKNK CLSTQRCDLH TLCPPDFTCS LSGKCCKLNI HCPDGTVPET 600
    SCQSASNHDH CPSSSHKCTL LNKEHFACCY SPGLVVEGSV TAEVSSECPI 650
    GSVEVDPRFG TSCRYSLQCP SPYFCNQRGQ QASGLVCTFS SCSNSNPCSV 700
    GTCNNGYCCS SGSNSGSAII DSDTNSTTNP SQPETTKTKN NTKKSNSSKK 750
    HRKPKKKDVD PLSDPLLQND FPIGPPGYGF PEHLSNLDEV LIRAQGDGVS 800
    CAGGFQSSLI CSVGSECPAG LHCDTAINLC CPLLLPLTDP KNPKKRKTKR 850
    RKQKQDENEM EASANFPDSD PARFSSYSCG CMGGGSSNCV GCQNAPQIIT 900
    IPQNSCPGGG YSVGGCSSGY CATGYSCIQN QCCPSYNSAP RISVYTCPSG 950
    GNAVGACMSG RCASGYTCSN NVCCPQTTTT NPFVCPDGTQ AAGGCVNGQC 1000
    GTGYTCSNGL CCAGTSTTVK CLDGSDAVGA CIPSCTGDGC GGVQVSYYCG 1050
    SGYTCTTGNI CCPINSCPNG GEVLGPTING LCPTGYTVQG NLCCSATCTD 1100
    GSTGLPSVNG VCIDGYSLTN GVCCPASVTC TDEISIGPCT GTGFNGGCPA 1150
    GYACDSNQVN CCPVVRYTDE SCQVGPAIDG LCPPGYVVVY IPNSPLITNG 1200
    VNPGTCIDLQ CTTGLCLTAN QIGDCDTATD AGTCPTGYTC FTNAGICCST 1250
    TTFSRLRIGN SRQMAQKPNY GRPLHSYMPP RFGGPSSSCS DGSLSSGPCM 1300
    NGLCGIGLEC QNGKCCSPSS NKPAGLLQSK CPSGDTAVSG CFPNGSCGTG 1350
    YECVSSLNLC CPPGQPQTFP SFPGNNNGFN INNNNRFGSL SMSPRPIGAR 1400
    CQLDGECVGQ AEGLSMCHAG VCQCSPIAYT QGIACVRRKS FQMNDDPVID 1450
    AANDDKSSSS VSV 1463

    Note: No experimental confirmation available.

    Length:1,463
    Mass (Da):153,114
    Last modified:September 18, 2013 - v8
    Checksum:i00A97AEFD99B3A7B
    GO
    Isoform b (identifier: P34504-1) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         165-165: P → R
         166-679: Missing.
         721-721: D → V
         722-882: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:788
    Mass (Da):80,380
    Checksum:iC0D85035108B37C1
    GO
    Isoform a (identifier: P34504-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         165-165: P → R
         166-679: Missing.
         721-721: D → V
         722-882: Missing.
         1281-1440: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:628
    Mass (Da):64,137
    Checksum:i15A4A67BF8383E9B
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei165 – 1651P → R in isoform a and isoform b. CuratedVSP_012169
    Alternative sequencei166 – 679514Missing in isoform a and isoform b. CuratedVSP_012168Add
    BLAST
    Alternative sequencei721 – 7211D → V in isoform a and isoform b. CuratedVSP_026510
    Alternative sequencei722 – 882161Missing in isoform a and isoform b. CuratedVSP_026511Add
    BLAST
    Alternative sequencei1281 – 1440160Missing in isoform a. CuratedVSP_002449Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z27078 Genomic DNA. Translation: CAA81587.2.
    Z27078 Genomic DNA. Translation: CAA81588.3.
    Z27078 Genomic DNA. Translation: CAH04706.4.
    PIRiB88553.
    S40992.
    S40994.
    RefSeqiNP_001022664.4. NM_001027493.5. [P34504-3]
    NP_499058.3. NM_066657.5. [P34504-1]
    NP_499059.2. NM_066658.4. [P34504-2]
    UniGeneiCel.24437.

    Genome annotation databases

    EnsemblMetazoaiK04H4.2c.1; K04H4.2c.1; WBGene00010573. [P34504-3]
    K04H4.2c.2; K04H4.2c.2; WBGene00010573. [P34504-3]
    K04H4.2c.3; K04H4.2c.3; WBGene00010573. [P34504-3]
    GeneIDi176315.
    KEGGicel:CELE_K04H4.2.
    UCSCiK04H4.2a.2. c. elegans. [P34504-1]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z27078 Genomic DNA. Translation: CAA81587.2 .
    Z27078 Genomic DNA. Translation: CAA81588.3 .
    Z27078 Genomic DNA. Translation: CAH04706.4 .
    PIRi B88553.
    S40992.
    S40994.
    RefSeqi NP_001022664.4. NM_001027493.5. [P34504-3 ]
    NP_499058.3. NM_066657.5. [P34504-1 ]
    NP_499059.2. NM_066658.4. [P34504-2 ]
    UniGenei Cel.24437.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 41513. 5 interactions.
    IntActi P34504. 11 interactions.
    MINTi MINT-116825.

    Proteomic databases

    PaxDbi P34504.
    PRIDEi P34504.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai K04H4.2c.1 ; K04H4.2c.1 ; WBGene00010573 . [P34504-3 ]
    K04H4.2c.2 ; K04H4.2c.2 ; WBGene00010573 . [P34504-3 ]
    K04H4.2c.3 ; K04H4.2c.3 ; WBGene00010573 . [P34504-3 ]
    GeneIDi 176315.
    KEGGi cel:CELE_K04H4.2.
    UCSCi K04H4.2a.2. c. elegans. [P34504-1 ]

    Organism-specific databases

    CTDi 176315.
    WormBasei K04H4.2a ; CE32463 ; WBGene00010573 .
    K04H4.2b ; CE36653 ; WBGene00010573 .
    K04H4.2c ; CE47897 ; WBGene00010573 .

    Phylogenomic databases

    eggNOGi NOG12793.
    GeneTreei ENSGT00730000113271.
    HOGENOMi HOG000019167.
    InParanoidi P34504.
    OMAi CTIDESC.

    Miscellaneous databases

    NextBioi 892054.

    Family and domain databases

    InterProi IPR007026. CC_domain.
    IPR002557. Chitin-bd_dom.
    IPR006150. Cys_repeat_1.
    [Graphical view ]
    Pfami PF04942. CC. 3 hits.
    [Graphical view ]
    SMARTi SM00494. ChtBD2. 1 hit.
    SM00289. WR1. 19 hits.
    [Graphical view ]
    SUPFAMi SSF57625. SSF57625. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.
    2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
      Strain: Bristol N2.

    Entry informationi

    Entry nameiYMV2_CAEEL
    AccessioniPrimary (citable) accession number: P34504
    Secondary accession number(s): P34505
    , P34506, P90907, Q6BEV9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: September 18, 2013
    Last modified: October 1, 2014
    This is version 118 of the entry and version 8 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3