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P34497 (GLNA_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glutamine synthetase

EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:gln-2
ORF Names:K03H1.1
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 367367Probable glutamine synthetase
PRO_0000153147

Sequences

Sequence LengthMass (Da)Tools
P34497 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: A7E0A3351F6D32F6

FASTA36741,284
        10         20         30         40         50         60 
MTHLNFETRM PLGTAVIDQF LGLRPHPTKI QATYVWIDGT GENLRSKTRT FDKLPKRIED 

        70         80         90        100        110        120 
YPIWNYDGSS TGQAKGRDSD RYLRPVAAYP DPFLGGGNKL VMCDTLDHQM QPTATSHRQA 

       130        140        150        160        170        180 
CAEIMHEIRD TRPWFGMEQE YLIVDRDEHP LGWPKHGFPD PQGKYYCSVG ADRAFGREVV 

       190        200        210        220        230        240 
ETHYRACLHA GLNIFGTNAE VTPGQWEFQI GTCEGIDMGD QLWMSRYILH RVAEQFGVCV 

       250        260        270        280        290        300 
SLDPKPKVTM GDWNGAGCHT NFSTAEMRAP GGIAAIEAAM TGLKRTHLEA MKVYDPHGGE 

       310        320        330        340        350        360 
DNLRRLTGRH ETSSADKFSW GVANRGCSIR IPRQVAAERK GYLEDRRPSS NCDPYQVTAM 


IAQSILF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z29560 Genomic DNA. Translation: CAA82655.1.
PIRS41024.
RefSeqNP_499208.1. NM_066807.3.
UniGeneCel.10322.

3D structure databases

ProteinModelPortalP34497.
SMRP34497. Positions 25-367.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP34497. 2 interactions.
STRING6239.K03H1.1.

Proteomic databases

PaxDbP34497.
PRIDEP34497.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaK03H1.1; K03H1.1; WBGene00001603.
GeneID176407.
KEGGcel:CELE_K03H1.1.
UCSCK03H1.1. c. elegans.

Organism-specific databases

CTD176407.
WormBaseK03H1.1; CE00507; WBGene00001603; gln-2.

Phylogenomic databases

eggNOGCOG0174.
GeneTreeENSGT00390000010047.
HOGENOMHOG000061500.
InParanoidP34497.
KOK01915.
OMARETRPWF.
OrthoDBEOG7CZK5G.
PhylomeDBP34497.

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio892444.

Entry information

Entry nameGLNA_CAEEL
AccessionPrimary (citable) accession number: P34497
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: June 11, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase