Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P34497

- GLNA_CAEEL

UniProt

P34497 - GLNA_CAEEL

Protein

Probable glutamine synthetase

Gene

gln-2

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutamine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glutamine synthetase (EC:6.3.1.2)
    Alternative name(s):
    Glutamate--ammonia ligase
    Gene namesi
    Name:gln-2
    ORF Names:K03H1.1
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome III

    Organism-specific databases

    WormBaseiK03H1.1; CE00507; WBGene00001603; gln-2.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 367367Probable glutamine synthetasePRO_0000153147Add
    BLAST

    Proteomic databases

    PaxDbiP34497.
    PRIDEiP34497.

    Interactioni

    Subunit structurei

    Homooctamer.By similarity

    Protein-protein interaction databases

    IntActiP34497. 2 interactions.
    STRINGi6239.K03H1.1.

    Structurei

    3D structure databases

    ProteinModelPortaliP34497.
    SMRiP34497. Positions 25-367.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutamine synthetase family.Curated

    Phylogenomic databases

    eggNOGiCOG0174.
    GeneTreeiENSGT00390000010047.
    HOGENOMiHOG000061500.
    InParanoidiP34497.
    KOiK01915.
    OMAiRETRPWF.
    OrthoDBiEOG7CZK5G.
    PhylomeDBiP34497.

    Family and domain databases

    Gene3Di3.30.590.10. 1 hit.
    InterProiIPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54368. SSF54368. 1 hit.
    PROSITEiPS00180. GLNA_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P34497-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTHLNFETRM PLGTAVIDQF LGLRPHPTKI QATYVWIDGT GENLRSKTRT    50
    FDKLPKRIED YPIWNYDGSS TGQAKGRDSD RYLRPVAAYP DPFLGGGNKL 100
    VMCDTLDHQM QPTATSHRQA CAEIMHEIRD TRPWFGMEQE YLIVDRDEHP 150
    LGWPKHGFPD PQGKYYCSVG ADRAFGREVV ETHYRACLHA GLNIFGTNAE 200
    VTPGQWEFQI GTCEGIDMGD QLWMSRYILH RVAEQFGVCV SLDPKPKVTM 250
    GDWNGAGCHT NFSTAEMRAP GGIAAIEAAM TGLKRTHLEA MKVYDPHGGE 300
    DNLRRLTGRH ETSSADKFSW GVANRGCSIR IPRQVAAERK GYLEDRRPSS 350
    NCDPYQVTAM IAQSILF 367
    Length:367
    Mass (Da):41,284
    Last modified:February 1, 1994 - v1
    Checksum:iA7E0A3351F6D32F6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z29560 Genomic DNA. Translation: CAA82655.1.
    PIRiS41024.
    RefSeqiNP_499208.1. NM_066807.3.
    UniGeneiCel.10322.

    Genome annotation databases

    EnsemblMetazoaiK03H1.1; K03H1.1; WBGene00001603.
    GeneIDi176407.
    KEGGicel:CELE_K03H1.1.
    UCSCiK03H1.1. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z29560 Genomic DNA. Translation: CAA82655.1 .
    PIRi S41024.
    RefSeqi NP_499208.1. NM_066807.3.
    UniGenei Cel.10322.

    3D structure databases

    ProteinModelPortali P34497.
    SMRi P34497. Positions 25-367.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P34497. 2 interactions.
    STRINGi 6239.K03H1.1.

    Proteomic databases

    PaxDbi P34497.
    PRIDEi P34497.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai K03H1.1 ; K03H1.1 ; WBGene00001603 .
    GeneIDi 176407.
    KEGGi cel:CELE_K03H1.1.
    UCSCi K03H1.1. c. elegans.

    Organism-specific databases

    CTDi 176407.
    WormBasei K03H1.1 ; CE00507 ; WBGene00001603 ; gln-2.

    Phylogenomic databases

    eggNOGi COG0174.
    GeneTreei ENSGT00390000010047.
    HOGENOMi HOG000061500.
    InParanoidi P34497.
    KOi K01915.
    OMAi RETRPWF.
    OrthoDBi EOG7CZK5G.
    PhylomeDBi P34497.

    Miscellaneous databases

    NextBioi 892444.

    Family and domain databases

    Gene3Di 3.30.590.10. 1 hit.
    InterProi IPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54368. SSF54368. 1 hit.
    PROSITEi PS00180. GLNA_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.
    2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiGLNA_CAEEL
    AccessioniPrimary (citable) accession number: P34497
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3