Reviewed, UniProtKB/Swiss-Prot P34480 (NAGA_CAEEL)

Names and origin

Protein names

Recommended name:
    Putative N-acetylglucosamine-6-phosphate deacetylase
    EC=3.5.1.25
Alternative name(s):
    GlcNAc 6-P deacetylase

Gene names

ORF Names:

F59B2.3

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	418 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
Sequence similarities	Belongs to the nagA family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	N-acetylglucosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetylglucosamine-6-phosphate deacetylase activity Inferred from electronic annotation. Source: EC protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
T03F6.3	Q9XVJ2	1	EBI-323530,EBI-323536

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 418	418	Putative N-acetylglucosamine-6-phosphate deacetylase		PRO_0000170912

Sequences

	Sequence		Length	Mass (Da)
	P34480-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 4988EA416F5D1247	FASTA	418	44,887
	10 20 30 40 50 60 MLPRKLKIDS TELAEITNEL VQFLNCLVLR SGGLKKEHIW VRNGRILDER TVFFEEKTMA 70 80 90 100 110 120 DVQIDCEGLI LSPGFIDLQL NGGFGIDFST YNSDDKEYQE GLALVAKQLL AHGVTSFSPT 130 140 150 160 170 180 VITSSPETYH KILPLLKPSN ASSEGAGNLG AHLEGPFISA DKRGCHPEQL VITSLSPNPV 190 200 210 220 230 240 EIIEHVYGST ENIAIVTMAP ELEGAQEAIE YFVSTGTTVS VGHSSAKLGP GEMAVLSGAK 250 260 270 280 290 300 MITHLFNAMQ SYHHRDPGLI GLLTSSKLTP DHPLYYGIIS DGIHTHDSAL RIAYHTNSAG 310 320 330 340 350 360 LVLVTDAIAA LGMSDGVHKL GTQTIHVKGL EAKLDGTNTT AGSVASMPYC IRHLMKATGC 370 380 390 400 410 PIEFALQSAT HKPATLLGVS DEKGTLDVGR LADFVLIDKN VTVKATFCSG KRVFLAQD

References

[1]

"2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans." Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L. , Gardner A., Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., Wohldman P. Nature 368:32-38(1994) [PubMed: 7906398] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

[2]

"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z11505 Genomic DNA. Translation: CAA77585.1.
PIR	S31124.
RefSeq	NP_498990.1.
UniGene	Cel.10376
3D structure databases
HSSP	HSSP built from PDB template 1O12 based on UniProtKB Q9WZS1.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:24730N.
IntAct	P34480. 2 interactions.
STRING	P34480.
Genome annotation databases
Ensembl	F59B2.3.1; F59B2.3.1; F59B2.3; Caenorhabditis elegans. [Genome view] F59B2.3.2; F59B2.3.2; F59B2.3; Caenorhabditis elegans. [Genome view]
GeneID	176272.
KEGG	cel:F59B2.3.
NMPDR	fig|6239.3.peg.11027.
UCSC	F59B2.3.2. c. elegans.
Organism-specific databases
CTD	176272.
WormBase	WBGene00010308. F59B2.3.
WormPep	F59B2.3. CE00231. [WorfDB]
Phylogenomic databases
OMA	ETMQIMH.
Enzyme and pathway databases
BRENDA	3.5.1.25. 672.
Gene expression databases
ArrayExpress	P34480.
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR003764. GlcNAc_6-P_deAcase. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00221. nagA. 1 hit.
ProtoNet	Search...
Other Resources
NextBio	891866.

Entry information

Entry name

NAGA_CAEEL

Accession

Primary (citable) accession number: P34480

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 3, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project