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Protein

Probable amino acid transporter skat-1

Gene

skat-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Plays a role in the accumulation of vital dyes and endogenous fluorescent compounds in lysosome related organelles. Has an effect on lysosome related organelle (LRO) function, in a pathway with serotonin.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Protein family/group databases

TCDBi2.A.18.8.8 the amino acid/auxin permease (aaap) family

Names & Taxonomyi

Protein namesi
Recommended name:
Probable amino acid transporter skat-11 Publication
Alternative name(s):
Protein suppressor of kat-1Imported
Gene namesi
Name:skat-1Imported
ORF Names:F59B2.2Imported
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF59B2.2 ; CE20899 ; WBGene00010307 ; skat-1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21
Transmembranei194 – 214HelicalSequence analysisAdd BLAST21
Transmembranei236 – 256HelicalSequence analysisAdd BLAST21
Transmembranei270 – 290HelicalSequence analysisAdd BLAST21
Transmembranei316 – 336HelicalSequence analysisAdd BLAST21
Transmembranei362 – 382HelicalSequence analysisAdd BLAST21
Transmembranei383 – 403HelicalSequence analysisAdd BLAST21
Transmembranei426 – 446HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000938311 – 460Probable amino acid transporter skat-1CuratedAdd BLAST460

Proteomic databases

EPDiP34479
PaxDbiP34479
PeptideAtlasiP34479

PTM databases

iPTMnetiP34479

Expressioni

Tissue specificityi

Expressed in the head, tail, body and ventral nerve cord neurons, muscles of the vulva, and intestine.1 Publication

Gene expression databases

BgeeiWBGene00010307

Interactioni

Protein-protein interaction databases

STRINGi6239.F59B2.2

Structurei

3D structure databases

ProteinModelPortaliP34479
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1304 Eukaryota
COG0814 LUCA
GeneTreeiENSGT00390000011245
HOGENOMiHOG000018109
InParanoidiP34479
OMAiHLAKKSD
OrthoDBiEOG091G06D2
PhylomeDBiP34479

Family and domain databases

InterProiView protein in InterPro
IPR013057 AA_transpt_TM
PfamiView protein in Pfam
PF01490 Aa_trans, 1 hit

Sequencei

Sequence statusi: Complete.

P34479-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEEGRERA VTVEGDAESM NDGRALVQPP ARSGDVITPT RAVLTLSKSM
60 70 80 90 100
FNAGCFSLPY AWKLGGLWVS FVMSFVIAGL NWYGNHILVR ASQHLAKKSD
110 120 130 140 150
RSALDYGHFA KKVCDYSDIR FLRNNSKAVM YFVNVTILFY QLGMCSVAIL
160 170 180 190 200
FISDNLVNLV GDHLGGTRHQ QMILMATVSL FFILLTNMFT EMRIVSFFAL
210 220 230 240 250
VSSVFFVIGA AVIMQYTVQQ PNQWDKLPAA TNFTGTITMI GMSMYAFEGQ
260 270 280 290 300
TMILPIENKL DNPAAFLAPF GVLSTTMIIC TAFMTALGFF GYTGFGDSIA
310 320 330 340 350
PTITTNVPKE GLYSTVNVFL MLQSLLGNSI AMYVVYDMFF NGFRRKFGAR
360 370 380 390 400
FPNVPKWLSD KGFRVFWVLV TYLMAVLIPK LEIMIPLVGV TSGALCALIF
410 420 430 440 450
PPFFEMITFW TDWKGLLTYR QRMTKIFINL VVMAIGVFAI IAGVYTNIHA
460
IIQSFSQPDP
Length:460
Mass (Da):51,338
Last modified:December 1, 2000 - v2
Checksum:i0D78809A84EF15BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z11505 Genomic DNA Translation: CAA77582.1
PIRiF88544
S31123
RefSeqiNP_498989.1, NM_066588.4
UniGeneiCel.6066

Genome annotation databases

EnsemblMetazoaiF59B2.2; F59B2.2; WBGene00010307
GeneIDi176271
KEGGicel:CELE_F59B2.2
UCSCiF59B2.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiSKAT1_CAEEL
AccessioniPrimary (citable) accession number: P34479
Secondary accession number(s): Q9U3E0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: December 1, 2000
Last modified: May 23, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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