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P34477 (UBC7_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable ubiquitin-conjugating enzyme E2 7

EC=6.3.2.19
Alternative name(s):
Ubiquitin carrier protein 7
Ubiquitin-protein ligase 7
Gene names
Name:ubc-7
ORF Names:F58A4.10
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length164 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the covalent attachment of ubiquitin to other proteins By similarity.

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ubiquitin-protein ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 164164Probable ubiquitin-conjugating enzyme E2 7
PRO_0000082516

Sites

Active site881Glycyl thioester intermediate By similarity

Secondary structure

....................... 164
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P34477 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 62580D9F3F8FD968

FASTA16418,939
        10         20         30         40         50         60 
MEQSSLLLKK QLADMRRVPV DGFSAGLVDD NDIYKWEVLV IGPPDTLYEG GFFKAILDFP 

        70         80         90        100        110        120 
RDYPQKPPKM KFISEIWHPN IDKEGNVCIS ILHDPGDDKW GYERPEERWL PVHTVETILL 

       130        140        150        160 
SVISMLTDPN FESPANVDAA KMQRENYAEF KKKVAQCVRR SQEE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z22179 Genomic DNA. Translation: CAA80166.1.
PIRS40982.
RefSeqNP_499133.1. NM_066732.4.
UniGeneCel.18114.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1PZVX-ray2.52A1-164[»]
ProteinModelPortalP34477.
SMRP34477. Positions 4-164.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.F58A4.10.1.

Proteomic databases

PaxDbP34477.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaF58A4.10.1; F58A4.10.1; F58A4.10.
F58A4.10.2; F58A4.10.2; F58A4.10.
GeneID176363.
KEGGcel:CELE_F58A4.10.
UCSCF58A4.10.1. c. elegans.

Organism-specific databases

CTD176363.
WormBaseF58A4.10; CE00216; WBGene00006704; ubc-7.

Phylogenomic databases

eggNOGCOG5078.
GeneTreeENSGT00730000110436.
HOGENOMHOG000233454.
InParanoidP34477.
KOK10575.
OMAFESPVFH.

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

Gene3D3.10.110.10. 1 hit.
InterProIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMSSF54495. SSF54495. 1 hit.
PROSITEPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP34477.
NextBio892258.
PROP34477.

Entry information

Entry nameUBC7_CAEEL
AccessionPrimary (citable) accession number: P34477
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: November 13, 2013
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

PATHWAY comments

Index of metabolic and biosynthesis pathways

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase