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P34442 (PTP5_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tyrosine-protein phosphatase F54C8.4

EC=3.1.3.48
Gene names
ORF Names:F54C8.4
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Probable tyrosine-protein phosphatase F54C8.4
PRO_0000094885

Regions

Compositional bias292 – 31019Asp/Glu-rich (highly acidic)

Sites

Active site1311Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
P34442 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 55BB1D1E6DC45935

FASTA35941,111
        10         20         30         40         50         60 
MVRVCRVVPK DWSKFQPVGN VIPRTRFIVF KTPINSQLST KIHKEQRFTT NDLFRQLSER 

        70         80         90        100        110        120 
GQYLGLVVDL SDTDRYYDKK DITGMCVQYE KVNCPGRGFI ERDDCVESFH QVIQDYTDKC 

       130        140        150        160        170        180 
DDPDALIGVH CTNGINRCGY LICRFLIDRL GWSSHEAIDA FEQARGYSIE KGAYVMALHK 

       190        200        210        220        230        240 
AAKDKRDKQV DSDSDSSERQ RKKKNKRKHR EIVEHENIVL INTIIGELGS QAASVSGTDY 

       250        260        270        280        290        300 
QNSPNGVSVD PGQPQPHHWG FAIKRSKYAQ LNQPVANGAN TPPEPSEGTP QEEEEFEEDF 

       310        320        330        340        350 
EEIEEETETE PGKGQSVSSK RRARRNRMQK YMQVMQRGRF HEIQAIREEV ALSHGSARD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z22178 Genomic DNA. Translation: CAA80156.1.
PIRS40746.
RefSeqNP_001254988.1. NM_001268059.1.
UniGeneCel.8899.

3D structure databases

ProteinModelPortalP34442.
SMRP34442. Positions 8-179.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-6669542.
STRING6239.F54C8.4.

Proteomic databases

PaxDbP34442.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaF54C8.4a; F54C8.4a; WBGene00010037.
GeneID176323.
KEGGcel:CELE_F54C8.4.
UCSCF54C8.4. c. elegans.

Organism-specific databases

CTD176323.
WormBaseF54C8.4a; CE00190; WBGene00010037.

Phylogenomic databases

eggNOGNOG252687.
GeneTreeENSGT00530000063473.
HOGENOMHOG000115789.
InParanoidP34442.
KOK01104.
OMAEIVEHEN.
PhylomeDBP34442.

Family and domain databases

Gene3D3.90.190.10. 1 hit.
InterProIPR000340. Dual-sp_phosphatase_cat-dom.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
[Graphical view]
PfamPF00782. DSPc. 1 hit.
[Graphical view]
SUPFAMSSF52799. SSF52799. 1 hit.
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio892094.

Entry information

Entry namePTP5_CAEEL
AccessionPrimary (citable) accession number: P34442
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: June 11, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase