P34391 (COL91_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative cuticle collagen 91

Gene names

Name:	col-91
ORF Names:	F09G8.6

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	278 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment By similarity.
Subunit structure	Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links By similarity.
Sequence similarities	Belongs to the cuticular collagen family.

Ontologies

Keywords
Cellular component	Cuticle
Domain	Collagen Repeat
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	collagen Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural constituent of cuticle Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 278	278	Putative cuticle collagen 91		PRO_0000127603
Regions
	Region	91 – 120	30	Triple-helical region
	Region	137 – 199	63	Triple-helical region
	Region	202 – 264	63	Triple-helical region

Sequences

	Sequence		Length	Mass (Da)
	P34391 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: E21A3B3EB925FA27	FASTA	278	26,228
	10 20 30 40 50 60 MPSASTISVI SAISGVAVLG ALLTATIIFN DINRFYYETM ETFDEFKINE KNAWDTMVMS 70 80 90 100 110 120 TRSPKEMLLG RARRQAALPD CQALAKNCPP GPPGPPGAPG AAGEPGVDGD AGAAGIDGVA 130 140 150 160 170 180 IQFASAAGGA CIQCPAGEAG PAGAPGAPGP AGPDGQPGAD GQGGAPGPAG PEGPAGDAGA 190 200 210 220 230 240 PGAPGAPGND GQPGQNGQRS TGTPGAAGAP GPQGPVGSDG QPGSAGAPGA PGPAGAPGVD 250 260 270 GQPGANGQPG PDGEQGHDGQ PGPDAAYCPC PARSSVRQ

References

[1]	"2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans." Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L. , Gardner A., Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., Wohldman P. Nature 368:32-38(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
[2]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FO080289 Genomic DNA. Translation: CCD62645.1.
PIR	S44796.
RefSeq	NP_498814.1. NM_066413.6.
3D structure databases
ProteinModelPortal	P34391.
SMR	P34391. Positions 138-174.
ModBase	Search...
Protein-protein interaction databases
STRING	6239.F09G8.6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	F09G8.6; F09G8.6; F09G8.6.
GeneID	184269.
KEGG	cel:CELE_F09G8.6.
UCSC	F09G8.6. c. elegans.
Organism-specific databases
CTD	184269.
WormBase	F09G8.6; CE00141; WBGene00000666; col-91.
Phylogenomic databases
eggNOG	NOG328768.
GeneTree	ENSGT00530000064217.
HOGENOM	HOG000085656.
InParanoid	P34391.
OMA	ALAKNCP.
Family and domain databases
InterPro	IPR002486. Col_cuticle_N. IPR008160. Collagen. [Graphical view]
Pfam	PF01484. Col_cuticle_N. 1 hit. PF01391. Collagen. 1 hit. [Graphical view]
SMART	SM01088. Col_cuticle_N. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	924146.

Entry information

Entry name

COL91_CAEEL

Accession

Primary (citable) accession number: P34391

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	May 1, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project