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P34337

- YK13_CAEEL

UniProt

P34337 - YK13_CAEEL

Protein

Putative tyrosine-protein phosphatase C15H7.3

Gene

C15H7.3

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tyrosine-protein phosphatase C15H7.3 (EC:3.1.3.48)
    Gene namesi
    ORF Names:C15H7.3
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome III

    Organism-specific databases

    WormBaseiC15H7.3; CE00081; WBGene00007610.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 398398Putative tyrosine-protein phosphatase C15H7.3PRO_0000094927Add
    BLAST

    Proteomic databases

    PaxDbiP34337.

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.C15H7.3.

    Structurei

    3D structure databases

    ProteinModelPortaliP34337.
    SMRiP34337. Positions 165-375.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini125 – 376252Tyrosine-protein phosphatasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 tyrosine-protein phosphatase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG327017.
    GeneTreeiENSGT00530000064500.
    HOGENOMiHOG000019963.
    InParanoidiP34337.
    OMAiHQESIAS.
    PhylomeDBiP34337.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view]
    PfamiPF00102. Y_phosphatase. 1 hit.
    [Graphical view]
    SMARTiSM00194. PTPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52799. SSF52799. 1 hit.
    PROSITEiPS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P34337-1 [UniParc]FASTAAdd to Basket

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    MERSQKSARK KKKTSKSGND RSIRSERKSK QKKPAGEKSQ KSRRTRKSRG    50
    PKGNGFTSRE TIQPSSSGQS EGTTRMDDQK DEKKDDKKEE KKEERKEEKK 100
    EEVKEPWSEE EPAKRMVANG FFTTTNVGGT FKQTDNFKTP MDSCPSFKNN 150
    MHKIRAPDCP IPEEKLVKLT NGPESFICAA KITVPDFNRT MILTQVPDLS 200
    SAPDIADFWR MIHQESIASV VIAVMPLEVT LQQILPLLSG TYSTYGKMFV 250
    NNKKVESAVG MTEYCLEIFP DGCSNSLLTT VYHLHNWRQK RGLEVVTDLV 300
    ATMEKVMKVN DNTVLMSMNG TGRAGTMLTL FTAMLQVQKG KEVNAKETLA 350
    SLRAERCGIV DNIDQFGTVH RSMACWFKNN STNEEVQRKV VEFAPSIQ 398
    Length:398
    Mass (Da):44,926
    Last modified:February 1, 1994 - v1
    Checksum:iCEEDE09FA0BC8F68
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z22173 Genomic DNA. Translation: CAA80125.1.
    PIRiS40752.
    RefSeqiNP_499135.1. NM_066734.5.
    UniGeneiCel.10838.

    Genome annotation databases

    EnsemblMetazoaiC15H7.3; C15H7.3; WBGene00007610.
    GeneIDi182639.
    KEGGicel:CELE_C15H7.3.
    UCSCiC15H7.3. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z22173 Genomic DNA. Translation: CAA80125.1 .
    PIRi S40752.
    RefSeqi NP_499135.1. NM_066734.5.
    UniGenei Cel.10838.

    3D structure databases

    ProteinModelPortali P34337.
    SMRi P34337. Positions 165-375.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.C15H7.3.

    Proteomic databases

    PaxDbi P34337.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai C15H7.3 ; C15H7.3 ; WBGene00007610 .
    GeneIDi 182639.
    KEGGi cel:CELE_C15H7.3.
    UCSCi C15H7.3. c. elegans.

    Organism-specific databases

    CTDi 182639.
    WormBasei C15H7.3 ; CE00081 ; WBGene00007610 .

    Phylogenomic databases

    eggNOGi NOG327017.
    GeneTreei ENSGT00530000064500.
    HOGENOMi HOG000019963.
    InParanoidi P34337.
    OMAi HQESIAS.
    PhylomeDBi P34337.

    Miscellaneous databases

    NextBioi 918298.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view ]
    Pfami PF00102. Y_phosphatase. 1 hit.
    [Graphical view ]
    SMARTi SM00194. PTPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52799. SSF52799. 1 hit.
    PROSITEi PS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.
    2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiYK13_CAEEL
    AccessioniPrimary (citable) accession number: P34337
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3