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Protein

Uncharacterized F-box/LRR-repeat protein C02F5.7

Gene

C02F5.7

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized F-box/LRR-repeat protein C02F5.7
Gene namesi
ORF Names:C02F5.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiC02F5.7a; CE24780; WBGene00015350.
C02F5.7b; CE30418; WBGene00015350.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Uncharacterized F-box/LRR-repeat protein C02F5.7PRO_0000119981Add
BLAST

Proteomic databases

EPDiP34284.
PaxDbiP34284.
PRIDEiP34284.

Interactioni

Protein-protein interaction databases

IntActiP34284. 2 interactions.
MINTiMINT-227871.
STRINGi6239.C02F5.7b.1.

Structurei

3D structure databases

ProteinModelPortaliP34284.
SMRiP34284. Positions 60-420.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini54 – 10047F-boxPROSITE-ProRule annotationAdd
BLAST
Repeati122 – 14726LRR 1Add
BLAST
Repeati148 – 17326LRR 2Add
BLAST
Repeati174 – 19926LRR 3Add
BLAST
Repeati200 – 22526LRR 4Add
BLAST
Repeati226 – 25126LRR 5Add
BLAST
Repeati252 – 27726LRR 6Add
BLAST
Repeati278 – 30326LRR 7Add
BLAST
Repeati304 – 32926LRR 8Add
BLAST
Repeati330 – 35526LRR 9Add
BLAST
Repeati356 – 38126LRR 10Add
BLAST
Repeati408 – 43326LRR 11Add
BLAST

Sequence similaritiesi

Contains 1 F-box domain.PROSITE-ProRule annotation
Contains 11 LRR (leucine-rich) repeats.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG4341. Eukaryota.
ENOG410XQ54. LUCA.
GeneTreeiENSGT00760000119059.
HOGENOMiHOG000230659.
InParanoidiP34284.
KOiK10268.
OMAiSKCVELT.
OrthoDBiEOG7CVPXM.
PhylomeDBiP34284.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR001810. F-box_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR006553. Leu-rich_rpt_Cys-con_subtyp.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
PF00560. LRR_1. 1 hit.
PF13516. LRR_6. 3 hits.
[Graphical view]
SMARTiSM00256. FBOX. 1 hit.
SM00367. LRR_CC. 11 hits.
[Graphical view]
PROSITEiPS50181. FBOX. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform b (identifier: P34284-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
METAERISAA ASAASSRRAK RLAQQAHKTH PVIQAKQNQM YLITTLSPAQ
60 70 80 90 100
VDNSLINRVL PKEVLLKVFS FLDTKALCRS AQVCRSWSIL ALDGSNWQRV
110 120 130 140 150
DLFTFQRDVK TAVVENLARR CGGFLKELSL KGCENVHDSA LRTFTSRCPN
160 170 180 190 200
LEHLSLYRCK RVTDASCENL GRYCHKLNYL NLENCSSITD RAMKYIGDGC
210 220 230 240 250
PNLSYLNISW CDAIQDRGVQ IILSNCKSLD TLILRGCEGL TENVFGSVEA
260 270 280 290 300
HMGAIKKLNL LQCFQLTDIT VQNIANGATA LEYLCMSNCN QISDRSLVSL
310 320 330 340 350
GQHSHNLKVL ELSGCTLLGD NGFIPLARGC RQLERLDMED CSLISDHTIN
360 370 380 390 400
SLANNCTALR ELSLSHCELI TDESIQNLAS KHRETLNVLE LDNCPQLTDS
410 420 430 440 450
TLSHLRHCKA LKRIDLYDCQ NVSKEAIVRF QHHRPNIEIH AYFAPVTPPT
460
DQVVNRGGIC RCCVIL
Note: No experimental confirmation available.
Length:466
Mass (Da):52,065
Last modified:October 25, 2005 - v3
Checksum:i05BCE82AA606E15F
GO
Isoform a (identifier: P34284-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     459-466: ICRCCVIL → MLF

Note: No experimental confirmation available.
Show »
Length:461
Mass (Da):51,552
Checksum:iBB28C98A5CA7B1D5
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei459 – 4668ICRCCVIL → MLF in isoform a. CuratedVSP_015950

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080288 Genomic DNA. Translation: CCD62632.1.
FO080288 Genomic DNA. Translation: CCD62633.1.
PIRiG88523.
S44609.
RefSeqiNP_741248.1. NM_171210.4. [P34284-1]
NP_741249.1. NM_171211.3. [P34284-2]
UniGeneiCel.35665.

Genome annotation databases

EnsemblMetazoaiC02F5.7b.1; C02F5.7b.1; WBGene00015350. [P34284-1]
C02F5.7b.2; C02F5.7b.2; WBGene00015350. [P34284-1]
GeneIDi3564805.
KEGGicel:CELE_C02F5.7.
UCSCiC02F5.7a.1. c. elegans. [P34284-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080288 Genomic DNA. Translation: CCD62632.1.
FO080288 Genomic DNA. Translation: CCD62633.1.
PIRiG88523.
S44609.
RefSeqiNP_741248.1. NM_171210.4. [P34284-1]
NP_741249.1. NM_171211.3. [P34284-2]
UniGeneiCel.35665.

3D structure databases

ProteinModelPortaliP34284.
SMRiP34284. Positions 60-420.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP34284. 2 interactions.
MINTiMINT-227871.
STRINGi6239.C02F5.7b.1.

Proteomic databases

EPDiP34284.
PaxDbiP34284.
PRIDEiP34284.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC02F5.7b.1; C02F5.7b.1; WBGene00015350. [P34284-1]
C02F5.7b.2; C02F5.7b.2; WBGene00015350. [P34284-1]
GeneIDi3564805.
KEGGicel:CELE_C02F5.7.
UCSCiC02F5.7a.1. c. elegans. [P34284-1]

Organism-specific databases

CTDi3564805.
WormBaseiC02F5.7a; CE24780; WBGene00015350.
C02F5.7b; CE30418; WBGene00015350.

Phylogenomic databases

eggNOGiKOG4341. Eukaryota.
ENOG410XQ54. LUCA.
GeneTreeiENSGT00760000119059.
HOGENOMiHOG000230659.
InParanoidiP34284.
KOiK10268.
OMAiSKCVELT.
OrthoDBiEOG7CVPXM.
PhylomeDBiP34284.

Miscellaneous databases

PROiP34284.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR001810. F-box_dom.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR006553. Leu-rich_rpt_Cys-con_subtyp.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
PF00560. LRR_1. 1 hit.
PF13516. LRR_6. 3 hits.
[Graphical view]
SMARTiSM00256. FBOX. 1 hit.
SM00367. LRR_CC. 11 hits.
[Graphical view]
PROSITEiPS50181. FBOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
    Strain: Bristol N2.

Entry informationi

Entry nameiYKK7_CAEEL
AccessioniPrimary (citable) accession number: P34284
Secondary accession number(s): Q8T3G0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: October 25, 2005
Last modified: June 8, 2016
This is version 125 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.