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P34275 (IVD_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable acyl coa dehydrogenase 6
Alternative name(s):
Probable isovaleryl-CoA dehydrogenase
Short name=IVD
EC=1.3.99.10
Gene names
Name:acdh-6
ORF Names:C02D5.1
OrganismCaenorhabditis elegans
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor.

Cofactor

FAD.

Pathway

Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3.

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the acyl-CoA dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 408408Probable acyl coa dehydrogenase 6
PRO_0000201191

Sites

Active site2651Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
P34275 [UniParc].

Last modified December 19, 2001. Version 2.
Checksum: A6351C6DCDCA962D

FASTA40845,326
        10         20         30         40         50         60 
MAFLARKTSS LLPATTSSTV KHMIYDEPHF AMQNSLAKLI KEKINPNVAQ WEKSGRYPAH 

        70         80         90        100        110        120 
FVFKMLGQLG VFAVNKPVDY GGTGRDFAMS IAIAEQIGAV DCGSIPMSVM VQSDMSTPAL 

       130        140        150        160        170        180 
AQFGSDSLRN RFLRPSINGD LVSSIAVSEP HAGSDVSAIR THARRYGSDL IINGSKMWIT 

       190        200        210        220        230        240 
NGDQADWACV LVNTSNAKNL HKNKSLVCIP LDSIGVHRST PLDKLGMRSS DTVQLFFEDV 

       250        260        270        280        290        300 
RVPSSYIIGE EGRGFAYQMN QFNDERLVTV AVGLLPLQKC INETIEYARE RLIFGKTLLD 

       310        320        330        340        350        360 
QQYVQFRLAE LEAELEATRS LLYRTVLARC QGEDVSMLTA MAKLKIGRLA RKVTDQCLQI 

       370        380        390        400 
WGGAGYLNDN GISRAFRDFR IFSIGAGCDE VMMQIIHKTQ SKRQQKRI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO080279 Genomic DNA. Translation: CCD62557.1.
PIRS44743.
RefSeqNP_498885.1. NM_066484.1.
UniGeneCel.10914.

3D structure databases

ProteinModelPortalP34275.
SMRP34275. Positions 23-400.
ModBaseSearch...

Protein-protein interaction databases

STRINGP34275.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaC02D5.1; C02D5.1; C02D5.1.
GeneID182112.
KEGGcel:C02D5.1.
NMPDRfig|6239.3.peg.10888.
UCSCC02D5.1. c. elegans.

Organism-specific databases

CTD182112.
WormBaseC02D5.1; CE24778; WBGene00015335; acdh-6.

Phylogenomic databases

eggNOGmeNOG08528.
GeneTreeEMGT00050000006171.
HOGENOMHBG699365.
InParanoidP34275.
OMAAFRDFRI.
PhylomeDBP34275.

Gene expression databases

ArrayExpressP34275.

Family and domain databases

InterProIPR006089. Acyl-CoA_DH_CS.
IPR006092. Acyl-CoA_DH_N.
IPR006090. Acyl-CoA_Oxase/DH_1.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase.
[Graphical view]
Gene3DG3DSA:2.40.110.10. Acyl_CoA_DH/ox_M. 1 hit.
G3DSA:1.10.540.10. AcylCoA_DH/ox_N. 1 hit.
G3DSA:1.20.140.10. AcylCoA_DH_1/2_C. 1 hit.
PfamPF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF02771. Acyl-CoA_dh_N. 1 hit.
[Graphical view]
SUPFAMSSF56645. AcylCoA_dehyd_NM. 1 hit.
SSF47203. AcylCoADH_C_like. 1 hit.
PROSITEPS00072. ACYL_COA_DH_1. 1 hit.
PS00073. ACYL_COA_DH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio916428.

Entry information

Entry nameIVD_CAEEL
AccessionPrimary (citable) accession number: P34275
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: December 19, 2001
Last modified: December 14, 2011
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families