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P34265 (KIN31_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 118. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tyrosine-protein kinase kin-31

EC=2.7.10.2
Gene names
Name:kin-31
ORF Names:B0523.1
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Contains 1 protein kinase domain.

Contains 1 SH2 domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 437437Probable tyrosine-protein kinase kin-31
PRO_0000088120

Regions

Domain20 – 11899SH2
Domain130 – 387258Protein kinase
Nucleotide binding136 – 1449ATP By similarity

Sites

Active site2561Proton acceptor By similarity
Binding site1591ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P34265 [UniParc].

Last modified October 24, 2003. Version 4.
Checksum: 603C1CBDBC1FAEC6

FASTA43749,394
        10         20         30         40         50         60 
MSINSLSNET PTPTIEKEAY FHGLIQREDV FQLLDNNGDY VVRLSDPKPG EPRSYILSVM 

        70         80         90        100        110        120 
FNNKLDENSS VKHFVINSVE NKYFVNNNMS FNTIQQMLSH YQKSRTEILE ACKILHPVRR 

       130        140        150        160        170        180 
QFWELDHGNI VIEKKLGEGA FGEVSSGVMK FKRGGRLVKV AVKQVKTDGI GKDQIKDFLM 

       190        200        210        220        230        240 
EARTMRNLGH PNIVRFLGIA VLQEPLFLVM ELATGGALDS YLKHNELLPI DKRHEMLLQA 

       250        260        270        280        290        300 
AWGLEYIHGK PMLHRDIAAR NCLYGDGKVK ISDFGLTRRG TIYQLHPETK SPIRWLAVCS 

       310        320        330        340        350        360 
QKTDVWAYGI LCWEIFNNGA EPYPGLTANE VAKQVTDGYR MPPHQLAAPE VQALMTRCCA 

       370        380        390        400        410        420 
ENPNDRPTMS DVAQILQRVT GQGRPNFAAI AKKEAEELLI MNSRSARRTS RRKGSNKKSA 

       430 
IPNGVLTPVN RAQEIKH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FO080165 Genomic DNA. Translation: CCD61728.1.
PIRG88535.
RefSeqNP_498912.3. NM_066511.5.
UniGeneCel.24327.

3D structure databases

ProteinModelPortalP34265.
SMRP34265. Positions 15-400.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.B0523.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaB0523.1; B0523.1; WBGene00002212.
GeneID176214.
KEGGcel:CELE_B0523.1.
UCSCB0523.1. c. elegans.

Organism-specific databases

CTD176214.
WormBaseB0523.1; CE33023; WBGene00002212; kin-31.

Phylogenomic databases

eggNOGCOG0515.
GeneTreeENSGT00750000117264.
HOGENOMHOG000233858.
InParanoidP34265.
KOK08253.
OMARCCAENP.
OrthoDBEOG708VXW.
PhylomeDBP34265.

Enzyme and pathway databases

SignaLinkP34265.

Family and domain databases

Gene3D3.30.505.10. 1 hit.
InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR000980. SH2.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
[Graphical view]
PfamPF07714. Pkinase_Tyr. 1 hit.
PF00017. SH2. 1 hit.
[Graphical view]
PRINTSPR00401. SH2DOMAIN.
PR00109. TYRKINASE.
SMARTSM00252. SH2. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMSSF55550. SSF55550. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS50001. SH2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio891608.

Entry information

Entry nameKIN31_CAEEL
AccessionPrimary (citable) accession number: P34265
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: October 24, 2003
Last modified: June 11, 2014
This is version 118 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase