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P34247 (UTP11_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
U3 small nucleolar RNA-associated protein 11

Short name=U3 snoRNA-associated protein 11
Alternative name(s):
U three protein 11
Gene names
Name:UTP11
Ordered Locus Names:YKL099C
ORF Names:YKL449
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in nucleolar processing of pre-18S ribosomal RNA. Ref.4

Subunit structure

Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with EBP2, FAF1, MPP10, RPS16A and RRP14. Ref.4 Ref.6 Ref.7

Subcellular location

Nucleusnucleolus Ref.4.

Sequence similarities

Belongs to the UTP11 family.

Sequence caution

The sequence CAA50458.1 differs from that shown. Reason: Frameshift at position 237.

The sequence CAA81939.1 differs from that shown. Reason: Frameshift at position 237.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 250250U3 small nucleolar RNA-associated protein 11
PRO_0000211052

Sequences

Sequence LengthMass (Da)Tools
P34247 [UniParc].

Last modified June 16, 2009. Version 2.
Checksum: AA013651708C4DB6

FASTA25029,735
        10         20         30         40         50         60 
MAKLVHDVQK KQHRERSQLT SRSRYGFLEK HKDYVKRAQD FHRKQSTLKV LREKAKERNP 

        70         80         90        100        110        120 
DEYYHAMHSR KTDAKGLLIS SRHGDEEDES LSMDQVKLLK TQDSNYVRTL RQIELKKLEK 

       130        140        150        160        170        180 
GAKQLMFKSS GNHTIFVDSR EKMNEFTPEK FFNTTSEMVN RSENRLTKDQ LAQDISNNRN 

       190        200        210        220        230        240 
ASSIMPKESL DKKKLKKFKQ VKQHLQRETQ LKQVQQRMDA QRELLKKGSK KKIVDSSGKI 

       250 
SFKWKKQRKR 

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence analysis of a 17 kb fragment of yeast chromosome XI physically localizes the MRB1 gene and reveals eight new open reading frames, including a homologue of the KIN1/KIN2 and SNF1 protein kinases."
Pallier C., Valens M., Puzos V., Fukuhara H., Cheret G., Sor F., Bolotin-Fukuhara M.
Yeast 9:1149-1155(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis."
Dragon F., Gallagher J.E.G., Compagnone-Post P.A., Mitchell B.M., Porwancher K.A., Wehner K.A., Wormsley S., Settlage R.E., Shabanowitz J., Osheim Y., Beyer A.L., Hunt D.F., Baserga S.J.
Nature 417:967-970(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INTERACTION WITH MPP10 AND SNORNA U3, IDENTIFICATION IN SSU PROCESSOME BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
[5]"Sequencing and comparison of yeast species to identify genes and regulatory elements."
Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION OF FRAMESHIFT.
[6]"Ebp2p, the yeast homolog of Epstein-Barr virus nuclear antigen 1-binding protein 2, interacts with factors of both the 60 S and the 40 s ribosomal subunit assembly."
Shirai C., Takai T., Nariai M., Horigome C., Mizuta K.
J. Biol. Chem. 279:25353-25358(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH EBP2; FAF1 AND RPS16A.
[7]"Yeast Rrp14p is a nucleolar protein involved in both ribosome biogenesis and cell polarity."
Yamada H., Horigome C., Okada T., Shirai C., Mizuta K.
RNA 13:1977-1987(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH RRP14.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X71133 Genomic DNA. Translation: CAA50458.1. Frameshift.
Z28099 Genomic DNA. Translation: CAA81939.1. Frameshift.
BK006944 Genomic DNA. Translation: DAA09058.1.
PIRS37926.
RefSeqNP_012823.2. NM_001179665.1.

3D structure databases

ProteinModelPortalP34247.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34034. 26 interactions.
DIPDIP-6569N.
IntActP34247. 4 interactions.
MINTMINT-8285535.
STRING4932.YKL099C.

Proteomic databases

MaxQBP34247.
PaxDbP34247.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKL099C; YKL099C; YKL099C.
GeneID853762.
KEGGsce:YKL099C.

Organism-specific databases

SGDS000001582. UTP11.

Phylogenomic databases

eggNOGCOG5223.
GeneTreeENSGT00390000005813.
HOGENOMHOG000231076.
KOK14769.
OMARVFNRPT.
OrthoDBEOG7HB5P3.

Enzyme and pathway databases

BioCycYEAST:G3O-31889-MONOMER.

Gene expression databases

GenevestigatorP34247.

Family and domain databases

InterProIPR007144. SSU_processome_Utp11.
[Graphical view]
PANTHERPTHR12838. PTHR12838. 1 hit.
PfamPF03998. Utp11. 1 hit.
[Graphical view]
PIRSFPIRSF015952. U3snoRNP11. 1 hit.
ProtoNetSearch...

Other

NextBio974846.
PROP34247.

Entry information

Entry nameUTP11_YEAST
AccessionPrimary (citable) accession number: P34247
Secondary accession number(s): D6VXI8
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: June 16, 2009
Last modified: May 14, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families