P34234 (LOT5_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein LOT5

Alternative name(s):
Low temperature-responsive protein 5

Gene names

Name:	LOT5
Ordered Locus Names:	YKL183W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cytoplasm. Nucleus Ref.5.
Induction	By cold. Ref.4
Miscellaneous	Present with 5930 molecules/cell in log phase SD medium. Ref.6
Sequence similarities	Belongs to the LOT5 family.

Ontologies

Keywords
Cellular component	Cytoplasm Nucleus
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from direct assay Ref.5. Source: SGD nucleus Inferred from direct assay Ref.5. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 306	306	Protein LOT5		PRO_0000203137

Sequences

	Sequence		Length	Mass (Da)
	P34234 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 4EF3CD0C7D4DF14D	FASTA	306	34,326
	10 20 30 40 50 60 MMKKKPKCQI ARTKPSVENV IPYNQFKKTQ PRFNGNFSAL NNEEYIILFG GGRDLILGSL 70 80 90 100 110 120 TPCSSSHLSN QANPQDTSEY GTDLFILNSC IIIWFNGLGY GLEIPYSSVL YHASRRLPDG 130 140 150 160 170 180 REGLQLEILL TLERDEVLDM LYQSLAPQAC EFDGEEAHAF TVRSVELTIR PKYSIYDRHY 190 200 210 220 230 240 NNEIETLFTF ENFGVNRGDD LVNNCNEALA VCMDLHGEDV QDQDQEQYQD PSMAFEGAQD 250 260 270 280 290 300 LNATYSGLGD TLHGPPVYQN DGLADDLDGD LVMDNVVSRG GPEASMSMEF YANQNLAGRK NSRDNE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequencing and analysis of 51.6 kilobases on the left arm of chromosome XI from Saccharomyces cerevisiae reveals 23 open reading frames including the FAS1 gene." Wiemann S., Voss H., Schwager C., Rupp T., Stegemann J., Zimmermann J., Grothues D., Sensen C., Erfle H., Hewitt N., Banrevi A., Ansorge W. Yeast 9:1343-1348(1993) [PubMed: 8154185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete DNA sequence of yeast chromosome XI." Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W. Nature 369:371-378(1994) [PubMed: 8196765] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Multiple mechanisms regulate expression of low temperature responsive (LOT) genes in Saccharomyces cerevisiae." Zhang L., Ohta A., Horiuchi H., Takagi M., Imai R. Biochem. Biophys. Res. Commun. 283:531-535(2001) [PubMed: 11327734] [Abstract] Cited for: INDUCTION.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X74151 Genomic DNA. Translation: CAA52255.1. Z28183 Genomic DNA. Translation: CAA82026.1. BK006944 Genomic DNA. Translation: DAA08984.1.
PIR	S34687.
RefSeq	NP_012738.1. NM_001179749.1.
3D structure databases
ProteinModelPortal	P34234.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1413N.
IntAct	P34234. 3 interactions.
MINT	MINT-392689.
STRING	P34234.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YKL183W; YKL183W; YKL183W.
GeneID	853652.
KEGG	sce:YKL183W.
NMPDR	fig|4932.3.peg.3716.
Organism-specific databases
CYGD	YKL183w.
SGD	S000001666. LOT5.
Phylogenomic databases
eggNOG	fuNOG11756.
HOGENOM	HBG202402.
OMA	QLTQPRL.
OrthoDB	EOG49W5QZ.
Gene expression databases
ArrayExpress	P34234.
Genevestigator	P34234.
GermOnline	YKL183W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	974566.

Entry information

Entry name

LOT5_YEAST

Accession

Primary (citable) accession number: P34234
Secondary accession number(s): D6VX18

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program