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Protein

mRNA transport regulator MTR2

Gene

MTR2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Affects mRNA transport from the nucleus to the cytoplasm.

GO - Biological processi

  • poly(A)+ mRNA export from nucleus Source: SGD
  • ribosomal large subunit export from nucleus Source: SGD
  • ribosomal small subunit export from nucleus Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-31949-MONOMER.

Protein family/group databases

TCDBi1.I.1.1.1. the nuclear pore complex (npc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
mRNA transport regulator MTR2
Gene namesi
Name:MTR2
Ordered Locus Names:YKL186C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XI

Organism-specific databases

EuPathDBiFungiDB:YKL186C.
SGDiS000001669. MTR2.

Subcellular locationi

GO - Cellular componenti

  • nuclear RNA export factor complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000966341 – 184mRNA transport regulator MTR2Add BLAST184

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei125PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP34232.
PRIDEiP34232.

PTM databases

iPTMnetiP34232.

Interactioni

Subunit structurei

Interacts with MEX67.1 Publication

Protein-protein interaction databases

BioGridi33936. 39 interactors.
DIPiDIP-4856N.
IntActiP34232. 8 interactors.
MINTiMINT-496382.

Structurei

Secondary structure

1184
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi15 – 31Combined sources17
Helixi39 – 42Combined sources4
Beta strandi47 – 49Combined sources3
Beta strandi52 – 54Combined sources3
Beta strandi57 – 60Combined sources4
Helixi62 – 72Combined sources11
Beta strandi77 – 88Combined sources12
Turni89 – 92Combined sources4
Beta strandi93 – 103Combined sources11
Beta strandi115 – 117Combined sources3
Beta strandi145 – 154Combined sources10
Helixi155 – 159Combined sources5
Beta strandi166 – 175Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OF5X-ray2.80B1-184[»]
4WWUX-ray3.30C/F/I/L1-184[»]
ProteinModelPortaliP34232.
SMRiP34232.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP34232.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000248726.
InParanoidiP34232.
KOiK14543.
OMAiVNCKVRF.
OrthoDBiEOG092C58Z7.

Family and domain databases

Gene3Di3.10.450.50. 1 hit.
InterProiIPR032710. NTF2-like_dom.
IPR019488. Nucl_pore_RNA_shuttling_Mtr2.
[Graphical view]
PfamiPF10429. Mtr2. 1 hit.
[Graphical view]
SUPFAMiSSF54427. SSF54427. 1 hit.

Sequencei

Sequence statusi: Complete.

P34232-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTNSNTMVM NDANQAQITA TFTKKILAHL DDPDSNKLAQ FVQLFNPNNC
60 70 80 90 100
RIIFNATPFA QATVFLQMWQ NQVVQTQHAL TGVDYHAIPG SGTLICNVNC
110 120 130 140 150
KVRFDESGRD KMGQDATVPI QPNNTGNRNR PNDMNKPRPL WGPYFGISLQ
160 170 180
LIIDDRIFRN DFNGVISGFN YNMVYKPEDS LLKI
Length:184
Mass (Da):20,784
Last modified:February 1, 1994 - v1
Checksum:iD3AE487A11FA2750
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S77467 Genomic DNA. Translation: AAB33484.1.
X74151 Genomic DNA. Translation: CAA52252.1.
Z28186 Genomic DNA. Translation: CAA82029.1.
AY558555 Genomic DNA. Translation: AAS56881.1.
BK006944 Genomic DNA. Translation: DAA08980.1.
PIRiS34684.
RefSeqiNP_012735.1. NM_001179752.1.

Genome annotation databases

EnsemblFungiiYKL186C; YKL186C; YKL186C.
GeneIDi853649.
KEGGisce:YKL186C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S77467 Genomic DNA. Translation: AAB33484.1.
X74151 Genomic DNA. Translation: CAA52252.1.
Z28186 Genomic DNA. Translation: CAA82029.1.
AY558555 Genomic DNA. Translation: AAS56881.1.
BK006944 Genomic DNA. Translation: DAA08980.1.
PIRiS34684.
RefSeqiNP_012735.1. NM_001179752.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OF5X-ray2.80B1-184[»]
4WWUX-ray3.30C/F/I/L1-184[»]
ProteinModelPortaliP34232.
SMRiP34232.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33936. 39 interactors.
DIPiDIP-4856N.
IntActiP34232. 8 interactors.
MINTiMINT-496382.

Protein family/group databases

TCDBi1.I.1.1.1. the nuclear pore complex (npc) family.

PTM databases

iPTMnetiP34232.

Proteomic databases

MaxQBiP34232.
PRIDEiP34232.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYKL186C; YKL186C; YKL186C.
GeneIDi853649.
KEGGisce:YKL186C.

Organism-specific databases

EuPathDBiFungiDB:YKL186C.
SGDiS000001669. MTR2.

Phylogenomic databases

HOGENOMiHOG000248726.
InParanoidiP34232.
KOiK14543.
OMAiVNCKVRF.
OrthoDBiEOG092C58Z7.

Enzyme and pathway databases

BioCyciYEAST:G3O-31949-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP34232.
PROiP34232.

Family and domain databases

Gene3Di3.10.450.50. 1 hit.
InterProiIPR032710. NTF2-like_dom.
IPR019488. Nucl_pore_RNA_shuttling_Mtr2.
[Graphical view]
PfamiPF10429. Mtr2. 1 hit.
[Graphical view]
SUPFAMiSSF54427. SSF54427. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMTR2_YEAST
AccessioniPrimary (citable) accession number: P34232
Secondary accession number(s): D6VX14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: November 2, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.