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Protein

Ras-related protein Rab-6.1

Gene

rab-6.1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Protein transport. Probably involved in vesicular traffic (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei43GTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 25GTPBy similarity8
Nucleotide bindingi66 – 70GTPBy similarity5
Nucleotide bindingi124 – 127GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein Rab-6.1
Gene namesi
Name:rab-6.1
ORF Names:F59B2.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF59B2.7 ; CE00234 ; WBGene00004269 ; rab-6.1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001211181 – 205Ras-related protein Rab-6.1Add BLAST205

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi203S-geranylgeranyl cysteineBy similarity1
Modified residuei205Cysteine methyl esterBy similarity1
Lipidationi205S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Methylation, Prenylation

Proteomic databases

EPDiP34213
PaxDbiP34213
PRIDEiP34213

Expressioni

Gene expression databases

BgeeiWBGene00004269
ExpressionAtlasiP34213 baseline and differential

Interactioni

Protein-protein interaction databases

BioGridi41474, 1 interactor
IntActiP34213, 1 interactor
STRINGi6239.F59B2.7.1

Structurei

3D structure databases

ProteinModelPortaliP34213
SMRiP34213
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0094 Eukaryota
ENOG410XPBI LUCA
GeneTreeiENSGT00910000144073
HOGENOMiHOG000233968
InParanoidiP34213
KOiK07893
OMAiPNIVIMN
OrthoDBiEOG091G0ORZ
PhylomeDBiP34213

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit

Sequencei

Sequence statusi: Complete.

P34213-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADFTNNALK KFKLVFLGEQ SVGKTSIITR FMYDSFDNTY QATIGIDFLS
60 70 80 90 100
KTMYLEDRTI RLQLWDTAGQ ERFRSLIPSY IRDSSVAVVV YDITNANSFH
110 120 130 140 150
QTTKWVDDVR NERGCDVIIV LVGNKTDLAD KRQVSTEDGE KKARDLNVMF
160 170 180 190 200
IETSAKAGYN VKQLFRKIAT ALPGIVQEET PEQPNIVIMN PPKDAEESQG

RQCPC
Length:205
Mass (Da):23,259
Last modified:February 1, 1994 - v1
Checksum:iA8A0876CF8E456C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z11505 Genomic DNA Translation: CAA77590.1
PIRiS31127
RefSeqiNP_498993.1, NM_066592.4
UniGeneiCel.10374

Genome annotation databases

EnsemblMetazoaiF59B2.7; F59B2.7; WBGene00004269
GeneIDi176275
KEGGicel:CELE_F59B2.7
UCSCiF59B2.7.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRAB6A_CAEEL
AccessioniPrimary (citable) accession number: P34213
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: May 23, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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