P34165D6VT85MFA1_YEASTMating hormone A-factor 1MFA1YDR461WD8035.5Saccharomyces cerevisiae (strain ATCC 204508 / S288c)Baker's yeastEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomycesStructure of genes encoding precursors of the yeast peptide mating pheromone a-factor.NUCLEOTIDE SEQUENCE [GENOMIC DNA]The a-factor pheromone of Saccharomyces cerevisiae is essential for mating.NUCLEOTIDE SEQUENCE [GENOMIC DNA]The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]The reference genome sequence of Saccharomyces cerevisiae: Then and now.GENOME REANNOTATIONApproaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.NUCLEOTIDE SEQUENCE [GENOMIC DNA]Amino acid sequences of a-factor mating peptides from Saccharomyces cerevisiae.PROTEIN SEQUENCE OF 22-33Structure of Saccharomyces cerevisiae mating hormone a-factor. Identification of S-farnesyl cysteine as a structural component.ISOPRENYLATION AT CYS-33METHYLATION AT CYS-33IDENTIFICATION BY MASS SPECTROMETRYGlobal analysis of protein expression in yeast.LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]The conformation of a-factor is not influenced by the S-prenylation of Cys12.STRUCTURE BY NMRThe active factor is excreted into the culture medium by haploid cells of the A mating type and acts on cells of the opposite mating type (type alpha). It mediates the conjugation process between the two types by inhibiting the initiation of DNA synthesis in type alpha cells and synchronizing them with type A.Cell membraneLipid-anchorCytoplasmic sidePresent with 28900 molecules/cell in log phase SD medium.Cell membraneDirect protein sequencingLipoproteinMembraneMethylationPheromonePrenylationReference proteomeMQPSTATAAPKEKTSSEKKDNYIIKGVFWDPACVIA
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