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Protein

M-factor

Gene

mfm1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

M-factor is a mating pheromone produced by M-type mating cells. All three mfm genes contribute to the production of M-factor.

GO - Molecular functioni

  • mating pheromone activity Source: PomBase

GO - Biological processi

  • conjugation with cellular fusion Source: PomBase
  • positive regulation of conjugation with cellular fusion Source: PomBase

Keywordsi

Molecular functionPheromone
Biological processStress response

Names & Taxonomyi

Protein namesi
Recommended name:
M-factor
Gene namesi
Name:mfm1
ORF Names:SPAPB8E5.05
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAPB8E5.05.
PomBaseiSPAPB8E5.05. mfm1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PropeptideiPRO_00000217071 – 301 PublicationAdd BLAST30
PeptideiPRO_000002170831 – 39M-factor9
PropeptideiPRO_000002170940 – 42Removed in mature form3

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei39Cysteine methyl ester1 Publication1
Lipidationi39S-farnesyl cysteine1 Publication1

Keywords - PTMi

Lipoprotein, Methylation, Prenylation

Proteomic databases

PRIDEiP34068.

Expressioni

Inductioni

By nitrogen starvation. It is further induced by a pheromone signal. Its transcription is limited to M cells.

Interactioni

GO - Molecular functioni

  • mating pheromone activity Source: PomBase

Protein-protein interaction databases

BioGridi279674. 15 interactors.
STRINGi4896.SPAPB8E5.05.1.

Family & Domainsi

Phylogenomic databases

PhylomeDBiP34068.

Family and domain databases

InterProiView protein in InterPro
IPR005555. M-factor.
PfamiView protein in Pfam
PF03855. M-factor. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD018891. M-factor. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P34068-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MDSMANSVSS SSVVNAGNKP AETLNKTVKN YTPKVPYMCV IA
Length:42
Mass (Da):4,448
Last modified:February 1, 1994 - v1
Checksum:iC78488648EE780F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63627 Genomic DNA. Translation: CAA45175.1.
CU329670 Genomic DNA. Translation: CAC37424.1.
PIRiS21027.
RefSeqiNP_594779.1. NM_001020207.2.

Genome annotation databases

EnsemblFungiiSPAPB8E5.05.1; SPAPB8E5.05.1:pep; SPAPB8E5.05.
GeneIDi2543246.
KEGGispo:SPAPB8E5.05.

Similar proteinsi

Entry informationi

Entry nameiMFM1_SCHPO
AccessioniPrimary (citable) accession number: P34068
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: July 5, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names