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Protein

Protein TraG

Gene

traG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Plays a crucial role in donor-recipient cell interactions. Required for two stages of the conjugation process: pilus biosynthesis and mating aggregate stabilization. May interact with TraN.

Caution

TraG is not responsible for the N-terminal acetylation of F pilin as stated by some authors.Curated

GO - Biological processi

Keywordsi

Biological processConjugation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TraG
Cleaved into the following chain:
Gene namesi
Name:traG
Ordered Locus Names:ECOK12F099
Encoded oniPlasmid F0 Publication
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 53CytoplasmicSequence analysisAdd BLAST53
Transmembranei54 – 73HelicalSequence analysisAdd BLAST20
Topological domaini74 – 329PeriplasmicSequence analysisAdd BLAST256
Transmembranei330 – 350HelicalSequence analysisAdd BLAST21
Topological domaini351 – 412CytoplasmicSequence analysisAdd BLAST62
Transmembranei413 – 433HelicalSequence analysisAdd BLAST21
Topological domaini434 – 938PeriplasmicSequence analysisAdd BLAST505

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000024502? – 938Protein TraG*
ChainiPRO_00000245011 – 938Protein TraGAdd BLAST938

Post-translational modificationi

TraG* probably arises from the post-translational cleavage of TraG.

Proteomic databases

PRIDEiP33790

Structurei

3D structure databases

ProteinModelPortaliP33790
SMRiP33790
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OMAiVASKSTW

Family and domain databases

InterProiView protein in InterPro
IPR012931 TraG_N
PfamiView protein in Pfam
PF07916 TraG_N, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33790-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEVYVIAGG EWLRNNLNAI AAFMGTWTWD SIEKIALTLS VLAVAVMWVQ
60 70 80 90 100
RHNVMDLLGW VAVFVLISLL VNVRTSVQII DNSDLVKVHR VDNVPVGLAM
110 120 130 140 150
PLSLTTRIGH AMVASYEMIF TQPDSVTYSK TGMLFGANLI VKSTDFLSRN
160 170 180 190 200
PEIINLFQDY VQNCVLGDIY LNHKYTLEDL MASADPYTLI FSRPSPLRGV
210 220 230 240 250
YDNNNNFITC KDASVTLKDR LNLDTKTGGK TWHYYVQQIF GGRPDPDLLF
260 270 280 290 300
RQLVSDSYSY FYGSSQSASQ IMRQNVTMNA LKEGITSNAA RNGDTASLVS
310 320 330 340 350
LATTSSMEKQ RLAHVSIGHV TMRNLPMVQT ILTGIAIGIF PLLILAAVFN
360 370 380 390 400
KLTLSVLKGY VFALMWLQTW PLLYAILNSA MTFYAKQNGA PVVLSELSQI
410 420 430 440 450
QLKYSNLAST AGYLSAMIPP LSWMMVKGLG AGFSSVYSHF ASSSISPTAS
460 470 480 490 500
AAGSVVDGNY SYGNMQTENV NGFSWSTNST TSFGQMMYQT GSGATATQTR
510 520 530 540 550
DGNMVMDASG AMSRLPVGIN ATRQIAAAQQ EMAREASNRA ESALHGFSSS
560 570 580 590 600
IASAWNTLSQ FGSNRGSSDS VTGGADSTMS AQDSMMASRM RSAVESYAKA
610 620 630 640 650
HNISNEQATR ELASRSTNAS LGLYGDAYAK GHLGISVLGN GGGVGLQAGA
660 670 680 690 700
KASIDGSDLD SHEASSGSRA SHDARHDIDA RATQDFKEAS DYFTSRKVSE
710 720 730 740 750
SGSHTDNNAD SRVDQLSAAL NSAKQSYDQY TTNMTRSHEY AEMASRTESM
760 770 780 790 800
SGQMSEDLSQ QFAQYVMKNA PQDVEAILTN TSSPEIAERR RAMAWSFVQE
810 820 830 840 850
QVQPGVDNTW RESRRDIGKG MESVPSGGGS QDIIADHQGH QAIIEQRTQD
860 870 880 890 900
SNIRNDVKHQ VDNMVTEYRG NIGDTQNSIR GEENIVKGQY SELQNHHKTE
910 920 930
ALTQNNKYNE EKLAQERIPG ADSPKELLEK AKSYQHKE
Length:938
Mass (Da):102,472
Last modified:February 1, 1994 - v1
Checksum:i9E09C8402ACDFDDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M59763 Genomic DNA Translation: AAA98081.1
U01159 Genomic DNA Translation: AAC44184.1
AP001918 Genomic DNA Translation: BAA97969.1
PIRiS20480
RefSeqiNP_061478.1, NC_002483.1
WP_001007055.1, NZ_CP014273.1

Genome annotation databases

GeneIDi1263567
PATRICifig|83333.107.peg.613

Similar proteinsi

Entry informationi

Entry nameiTRAG1_ECOLI
AccessioniPrimary (citable) accession number: P33790
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid

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