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P33779

- NTCA_SYNY3

UniProt

P33779 - NTCA_SYNY3

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Protein
Global nitrogen regulator
Gene
ntcA, sll1423
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi9 – 131123cNMP
Add
BLAST
DNA bindingi177 – 19620H-T-H motif By similarity
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Global nitrogen regulator
Gene namesi
Name:ntcA
Ordered Locus Names:sll1423
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 225225Global nitrogen regulator
PRO_0000100187Add
BLAST

Proteomic databases

PaxDbiP33779.

Interactioni

Protein-protein interaction databases

IntActiP33779. 1 interaction.
STRINGi1148.sll1423.

Structurei

3D structure databases

ProteinModelPortaliP33779.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini145 – 21874HTH crp-type
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0664.
HOGENOMiHOG000232503.
OMAiRFFANEL.
OrthoDBiEOG6QRWC5.
PhylomeDBiP33779.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR022299. Tscrpt_reg_NtcA.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00027. cNMP_binding. 1 hit.
[Graphical view]
PRINTSiPR00034. HTHCRP.
SMARTiSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
TIGRFAMsiTIGR03697. NtcA_cyano. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P33779-1 [UniParc]FASTAAdd to Basket

« Hide

MDQSLTQDRP LAAVFRRLGS ELMPPVVETF DRSKTIFFPG DPAERVYFLL    50
KGAVKLSRVY EAGEEITVAL LRENSVFGVL SLVTGQRSDR FYHAVAFTPV 100
ELLSAPIEQV EQALKEHPDL SLLMLQGLSS RILQTEMMIE TLAHRDMGSR 150
LVSFLLILCR DFGVPAPDGI RIDLKLSHQA IAEAIGSTRV TVTRLLGDLR 200
EGNMISITKK KITVHNPVAL SQQFT 225
Length:225
Mass (Da):25,046
Last modified:February 1, 1994 - v1
Checksum:iF1EE6555757E7379
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X71607 Genomic DNA. Translation: CAA50607.1.
BA000022 Genomic DNA. Translation: BAA18011.1.
PIRiA48640.
RefSeqiNP_441331.1. NC_000911.1.
YP_005651388.1. NC_017277.1.
YP_007451213.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA18011; BAA18011; BAA18011.
GeneIDi954677.
KEGGisyn:sll1423.
syy:SYNGTS_1435.
syz:MYO_114480.
PATRICi23840032. VBISynSp132158_1576.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X71607 Genomic DNA. Translation: CAA50607.1 .
BA000022 Genomic DNA. Translation: BAA18011.1 .
PIRi A48640.
RefSeqi NP_441331.1. NC_000911.1.
YP_005651388.1. NC_017277.1.
YP_007451213.1. NC_020286.1.

3D structure databases

ProteinModelPortali P33779.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P33779. 1 interaction.
STRINGi 1148.sll1423.

Proteomic databases

PaxDbi P33779.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA18011 ; BAA18011 ; BAA18011 .
GeneIDi 954677.
KEGGi syn:sll1423.
syy:SYNGTS_1435.
syz:MYO_114480.
PATRICi 23840032. VBISynSp132158_1576.

Phylogenomic databases

eggNOGi COG0664.
HOGENOMi HOG000232503.
OMAi RFFANEL.
OrthoDBi EOG6QRWC5.
PhylomeDBi P33779.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProi IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR022299. Tscrpt_reg_NtcA.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00027. cNMP_binding. 1 hit.
[Graphical view ]
PRINTSi PR00034. HTHCRP.
SMARTi SM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view ]
SUPFAMi SSF51206. SSF51206. 1 hit.
TIGRFAMsi TIGR03697. NtcA_cyano. 1 hit.
PROSITEi PS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "General distribution of the nitrogen control gene ntcA in cyanobacteria."
    Frias J.E., Merida A., Herrero A., Martin-Nieto J.M., Flores E.
    J. Bacteriol. 175:5710-5713(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiNTCA_SYNY3
AccessioniPrimary (citable) accession number: P33779
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: July 9, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi