Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P33772

- AMIA_SALTY

UniProt

P33772 - AMIA_SALTY

Protein

N-acetylmuramoyl-L-alanine amidase AmiA

Gene

amiA

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cell-wall hydrolase involved in septum cleavage during cell division.By similarity

    Catalytic activityi

    Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

    GO - Molecular functioni

    1. N-acetylmuramoyl-L-alanine amidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. peptidoglycan catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Cell wall biogenesis/degradation

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-2466-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-acetylmuramoyl-L-alanine amidase AmiA (EC:3.5.1.28)
    Gene namesi
    Name:amiA
    Ordered Locus Names:STM2450
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    Subcellular locationi

    Periplasm By similarity

    GO - Cellular componenti

    1. periplasmic space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Periplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3434Tat-type signalSequence AnalysisAdd
    BLAST
    Chaini35 – 289255N-acetylmuramoyl-L-alanine amidase AmiAPRO_0000006461Add
    BLAST

    Post-translational modificationi

    Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

    Proteomic databases

    PaxDbiP33772.
    PRIDEiP33772.

    Interactioni

    Protein-protein interaction databases

    STRINGi99287.STM2450.

    Structurei

    3D structure databases

    ProteinModelPortaliP33772.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG0860.
    HOGENOMiHOG000263827.
    KOiK01448.
    OMAiSYFNWFD.
    OrthoDBiEOG6CP3X3.
    PhylomeDBiP33772.

    Family and domain databases

    Gene3Di3.40.630.40. 2 hits.
    InterProiIPR002508. CW_Hdrlase/autolysin_cat.
    [Graphical view]
    PfamiPF01520. Amidase_3. 1 hit.
    [Graphical view]
    SMARTiSM00646. Ami_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P33772-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTFKLLKTL TSRRQVLKTG LAALTLSGMS HAVAKEETLK TSNGHSKPKT    50
    KKTGSKRLVM LDPGHGGIDT GAIGRNGSQE KHVVLAIAKN VRAILRNHGI 100
    DARLTRTGDT FIPLYDRVEI AHKHGADLFM SIHADGFTNP KAAGASVFAL 150
    SNRGASSAMA KYLSERENRA DEVAGKKATD RDHLLQQVLF DLVQTDTIKN 200
    SLTLGSHILK KIKPIHKLHS RTTEQAAFVV LKSPSIPSVL VETSFITNPE 250
    EERLLGTTAF RQKIATAIAN GIISYFHWFD NQKAHTKKR 289
    Length:289
    Mass (Da):31,659
    Last modified:February 1, 1994 - v1
    Checksum:i8FCC21089D56F671
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L19503 Genomic DNA. Translation: AAA27138.1.
    AE006468 Genomic DNA. Translation: AAL21344.1.
    PIRiA53302.
    RefSeqiNP_461385.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL21344; AAL21344; STM2450.
    GeneIDi1253972.
    KEGGistm:STM2450.
    PATRICi32383531. VBISalEnt20916_2588.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L19503 Genomic DNA. Translation: AAA27138.1 .
    AE006468 Genomic DNA. Translation: AAL21344.1 .
    PIRi A53302.
    RefSeqi NP_461385.1. NC_003197.1.

    3D structure databases

    ProteinModelPortali P33772.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 99287.STM2450.

    Proteomic databases

    PaxDbi P33772.
    PRIDEi P33772.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL21344 ; AAL21344 ; STM2450 .
    GeneIDi 1253972.
    KEGGi stm:STM2450.
    PATRICi 32383531. VBISalEnt20916_2588.

    Phylogenomic databases

    eggNOGi COG0860.
    HOGENOMi HOG000263827.
    KOi K01448.
    OMAi SYFNWFD.
    OrthoDBi EOG6CP3X3.
    PhylomeDBi P33772.

    Enzyme and pathway databases

    BioCyci SENT99287:GCTI-2466-MONOMER.

    Family and domain databases

    Gene3Di 3.40.630.40. 2 hits.
    InterProi IPR002508. CW_Hdrlase/autolysin_cat.
    [Graphical view ]
    Pfami PF01520. Amidase_3. 1 hit.
    [Graphical view ]
    SMARTi SM00646. Ami_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "An oxygen-dependent coproporphyrinogen oxidase encoded by the hemF gene of Salmonella typhimurium."
      Xu K., Elliott T.
      J. Bacteriol. 175:4990-4999(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: LT2.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720.

    Entry informationi

    Entry nameiAMIA_SALTY
    AccessioniPrimary (citable) accession number: P33772
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3