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P33772

- AMIA_SALTY

UniProt

P33772 - AMIA_SALTY

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Protein

N-acetylmuramoyl-L-alanine amidase AmiA

Gene

amiA

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cell-wall hydrolase involved in septum cleavage during cell division.By similarity

Catalytic activityi

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

GO - Molecular functioni

  1. N-acetylmuramoyl-L-alanine amidase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Cell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciSENT99287:GCTI-2466-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
N-acetylmuramoyl-L-alanine amidase AmiA (EC:3.5.1.28)
Gene namesi
Name:amiA
Ordered Locus Names:STM2450
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

Subcellular locationi

Periplasm By similarity

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3434Tat-type signalSequence AnalysisAdd
BLAST
Chaini35 – 289255N-acetylmuramoyl-L-alanine amidase AmiAPRO_0000006461Add
BLAST

Post-translational modificationi

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Proteomic databases

PaxDbiP33772.
PRIDEiP33772.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM2450.

Structurei

3D structure databases

ProteinModelPortaliP33772.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0860.
HOGENOMiHOG000263827.
KOiK01448.
OMAiSYFNWFD.
OrthoDBiEOG6CP3X3.
PhylomeDBiP33772.

Family and domain databases

Gene3Di3.40.630.40. 2 hits.
InterProiIPR002508. CW_Hdrlase/autolysin_cat.
[Graphical view]
PfamiPF01520. Amidase_3. 1 hit.
[Graphical view]
SMARTiSM00646. Ami_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33772-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTFKLLKTL TSRRQVLKTG LAALTLSGMS HAVAKEETLK TSNGHSKPKT
60 70 80 90 100
KKTGSKRLVM LDPGHGGIDT GAIGRNGSQE KHVVLAIAKN VRAILRNHGI
110 120 130 140 150
DARLTRTGDT FIPLYDRVEI AHKHGADLFM SIHADGFTNP KAAGASVFAL
160 170 180 190 200
SNRGASSAMA KYLSERENRA DEVAGKKATD RDHLLQQVLF DLVQTDTIKN
210 220 230 240 250
SLTLGSHILK KIKPIHKLHS RTTEQAAFVV LKSPSIPSVL VETSFITNPE
260 270 280
EERLLGTTAF RQKIATAIAN GIISYFHWFD NQKAHTKKR
Length:289
Mass (Da):31,659
Last modified:February 1, 1994 - v1
Checksum:i8FCC21089D56F671
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L19503 Genomic DNA. Translation: AAA27138.1.
AE006468 Genomic DNA. Translation: AAL21344.1.
PIRiA53302.
RefSeqiNP_461385.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL21344; AAL21344; STM2450.
GeneIDi1253972.
KEGGistm:STM2450.
PATRICi32383531. VBISalEnt20916_2588.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L19503 Genomic DNA. Translation: AAA27138.1 .
AE006468 Genomic DNA. Translation: AAL21344.1 .
PIRi A53302.
RefSeqi NP_461385.1. NC_003197.1.

3D structure databases

ProteinModelPortali P33772.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 99287.STM2450.

Proteomic databases

PaxDbi P33772.
PRIDEi P33772.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL21344 ; AAL21344 ; STM2450 .
GeneIDi 1253972.
KEGGi stm:STM2450.
PATRICi 32383531. VBISalEnt20916_2588.

Phylogenomic databases

eggNOGi COG0860.
HOGENOMi HOG000263827.
KOi K01448.
OMAi SYFNWFD.
OrthoDBi EOG6CP3X3.
PhylomeDBi P33772.

Enzyme and pathway databases

BioCyci SENT99287:GCTI-2466-MONOMER.

Family and domain databases

Gene3Di 3.40.630.40. 2 hits.
InterProi IPR002508. CW_Hdrlase/autolysin_cat.
[Graphical view ]
Pfami PF01520. Amidase_3. 1 hit.
[Graphical view ]
SMARTi SM00646. Ami_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "An oxygen-dependent coproporphyrinogen oxidase encoded by the hemF gene of Salmonella typhimurium."
    Xu K., Elliott T.
    J. Bacteriol. 175:4990-4999(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: LT2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiAMIA_SALTY
AccessioniPrimary (citable) accession number: P33772
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: October 29, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3