Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

37S ribosomal protein S5, mitochondrial

Gene

MRPS5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • RNA binding Source: InterPro
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29177-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
37S ribosomal protein S5, mitochondrial
Gene namesi
Name:MRPS5
Ordered Locus Names:YBR251W
ORF Names:YBR1704
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome II

Organism-specific databases

CYGDiYBR251w.
EuPathDBiFungiDB:YBR251W.
SGDiS000000455. MRPS5.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 1313MitochondrionSequence AnalysisAdd
BLAST
Chaini14 – 30729437S ribosomal protein S5, mitochondrialPRO_0000131688Add
BLAST

Proteomic databases

MaxQBiP33759.
PaxDbiP33759.
PeptideAtlasiP33759.

Interactioni

Subunit structurei

Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

Protein-protein interaction databases

BioGridi32946. 59 interactions.
DIPiDIP-2869N.
IntActiP33759. 44 interactions.
MINTiMINT-615779.
STRINGi4932.YBR251W.

Structurei

3D structure databases

ProteinModelPortaliP33759.
SMRiP33759. Positions 147-294.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini144 – 20865S5 DRBMPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ribosomal protein S5P family.Curated
Contains 1 S5 DRBM domain.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0098.
GeneTreeiENSGT00390000001878.
HOGENOMiHOG000247984.
InParanoidiP33759.
KOiK02988.
OMAiICECAGI.
OrthoDBiEOG7TJ3TZ.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
3.30.230.10. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000851. Ribosomal_S5.
IPR005324. Ribosomal_S5_C.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR013810. Ribosomal_S5_N.
IPR018192. Ribosomal_S5_N_CS.
[Graphical view]
PANTHERiPTHR13718. PTHR13718. 1 hit.
PfamiPF00333. Ribosomal_S5. 1 hit.
PF03719. Ribosomal_S5_C. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiPS00585. RIBOSOMAL_S5. 1 hit.
PS50881. S5_DSRBD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33759-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKRQLSTSV RYLQHYDESL LSRYYPESLL KSIKLAQQTI PEDTKFRVSR
60 70 80 90 100
NVEFAPPYLD DFTKIHPFWD YKPGMPHLHA QEENNNFSIF RWDQVQQPLP
110 120 130 140 150
GEGNILPPGV SLPNDGGRKS KSADVAAGLH KQTGVDPDYI TRKLTMKPLV
160 170 180 190 200
MKRVSNQTGK GKIASFYALV VVGDKNGMVG LGEGKSREEM SKAIFKAHWD
210 220 230 240 250
AVRNLKEIPR YENRTIYGDI DFRYHGVKLH LRSAKPGFGL RVNHVIFEIC
260 270 280 290 300
ECAGIKDLSG KVYKSRNDMN IAKGTIEAFT KAQKTLDEVA LGRGKKLVDV

RKVYYSS
Length:307
Mass (Da):34,883
Last modified:February 1, 1994 - v1
Checksum:i7A7BC49A4D414FC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20296 Genomic DNA. Translation: AAA65610.1.
Z36120 Genomic DNA. Translation: CAA85214.1.
BK006936 Genomic DNA. Translation: DAA07367.1.
PIRiS38374.
RefSeqiNP_009810.3. NM_001178599.3.

Genome annotation databases

EnsemblFungiiYBR251W; YBR251W; YBR251W.
GeneIDi852553.
KEGGisce:YBR251W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20296 Genomic DNA. Translation: AAA65610.1.
Z36120 Genomic DNA. Translation: CAA85214.1.
BK006936 Genomic DNA. Translation: DAA07367.1.
PIRiS38374.
RefSeqiNP_009810.3. NM_001178599.3.

3D structure databases

ProteinModelPortaliP33759.
SMRiP33759. Positions 147-294.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32946. 59 interactions.
DIPiDIP-2869N.
IntActiP33759. 44 interactions.
MINTiMINT-615779.
STRINGi4932.YBR251W.

Proteomic databases

MaxQBiP33759.
PaxDbiP33759.
PeptideAtlasiP33759.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBR251W; YBR251W; YBR251W.
GeneIDi852553.
KEGGisce:YBR251W.

Organism-specific databases

CYGDiYBR251w.
EuPathDBiFungiDB:YBR251W.
SGDiS000000455. MRPS5.

Phylogenomic databases

eggNOGiCOG0098.
GeneTreeiENSGT00390000001878.
HOGENOMiHOG000247984.
InParanoidiP33759.
KOiK02988.
OMAiICECAGI.
OrthoDBiEOG7TJ3TZ.

Enzyme and pathway databases

BioCyciYEAST:G3O-29177-MONOMER.

Miscellaneous databases

NextBioi971646.
PROiP33759.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
3.30.230.10. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000851. Ribosomal_S5.
IPR005324. Ribosomal_S5_C.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR013810. Ribosomal_S5_N.
IPR018192. Ribosomal_S5_N_CS.
[Graphical view]
PANTHERiPTHR13718. PTHR13718. 1 hit.
PfamiPF00333. Ribosomal_S5. 1 hit.
PF03719. Ribosomal_S5_C. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiPS00585. RIBOSOMAL_S5. 1 hit.
PS50881. S5_DSRBD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The complete sequence of a 6794 bp segment located on the right arm of chromosome II of Saccharomyces cerevisiae. Finding of a putative dUTPase in a yeast."
    Doignon F., Biteau N., Aigle M., Crouzet M.
    Yeast 9:1131-1137(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. "Complete DNA sequence of yeast chromosome II."
    Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
    , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
    EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues."
    Saveanu C., Fromont-Racine M., Harington A., Ricard F., Namane A., Jacquier A.
    J. Biol. Chem. 276:15861-15867(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  5. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
    Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
    Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.

Entry informationi

Entry nameiRT05_YEAST
AccessioniPrimary (citable) accession number: P33759
Secondary accession number(s): D6VQP7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: June 24, 2015
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 6680 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.