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P33759

- RT05_YEAST

UniProt

P33759 - RT05_YEAST

Protein

37S ribosomal protein S5, mitochondrial

Gene

MRPS5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 115 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. RNA binding Source: InterPro
    2. structural constituent of ribosome Source: SGD

    GO - Biological processi

    1. mitochondrial translation Source: SGD

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    BioCyciYEAST:G3O-29177-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    37S ribosomal protein S5, mitochondrial
    Gene namesi
    Name:MRPS5
    Ordered Locus Names:YBR251W
    ORF Names:YBR1704
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome II

    Organism-specific databases

    CYGDiYBR251w.
    SGDiS000000455. MRPS5.

    Subcellular locationi

    Mitochondrion 2 Publications

    GO - Cellular componenti

    1. mitochondrial small ribosomal subunit Source: SGD

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 1313MitochondrionSequence AnalysisAdd
    BLAST
    Chaini14 – 30729437S ribosomal protein S5, mitochondrialPRO_0000131688Add
    BLAST

    Proteomic databases

    MaxQBiP33759.
    PaxDbiP33759.
    PeptideAtlasiP33759.

    Expressioni

    Gene expression databases

    GenevestigatoriP33759.

    Interactioni

    Subunit structurei

    Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

    Protein-protein interaction databases

    BioGridi32946. 57 interactions.
    DIPiDIP-2869N.
    IntActiP33759. 44 interactions.
    MINTiMINT-615779.
    STRINGi4932.YBR251W.

    Structurei

    3D structure databases

    ProteinModelPortaliP33759.
    SMRiP33759. Positions 147-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini144 – 20865S5 DRBMPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ribosomal protein S5P family.Curated
    Contains 1 S5 DRBM domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiCOG0098.
    GeneTreeiENSGT00390000001878.
    HOGENOMiHOG000247984.
    KOiK02988.
    OMAiICECAGI.
    OrthoDBiEOG7TJ3TZ.

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    3.30.230.10. 1 hit.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR000851. Ribosomal_S5.
    IPR005324. Ribosomal_S5_C.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR013810. Ribosomal_S5_N.
    IPR018192. Ribosomal_S5_N_CS.
    [Graphical view]
    PANTHERiPTHR13718. PTHR13718. 1 hit.
    PfamiPF00333. Ribosomal_S5. 1 hit.
    PF03719. Ribosomal_S5_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    PROSITEiPS00585. RIBOSOMAL_S5. 1 hit.
    PS50881. S5_DSRBD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P33759-1 [UniParc]FASTAAdd to Basket

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    MFKRQLSTSV RYLQHYDESL LSRYYPESLL KSIKLAQQTI PEDTKFRVSR    50
    NVEFAPPYLD DFTKIHPFWD YKPGMPHLHA QEENNNFSIF RWDQVQQPLP 100
    GEGNILPPGV SLPNDGGRKS KSADVAAGLH KQTGVDPDYI TRKLTMKPLV 150
    MKRVSNQTGK GKIASFYALV VVGDKNGMVG LGEGKSREEM SKAIFKAHWD 200
    AVRNLKEIPR YENRTIYGDI DFRYHGVKLH LRSAKPGFGL RVNHVIFEIC 250
    ECAGIKDLSG KVYKSRNDMN IAKGTIEAFT KAQKTLDEVA LGRGKKLVDV 300
    RKVYYSS 307
    Length:307
    Mass (Da):34,883
    Last modified:February 1, 1994 - v1
    Checksum:i7A7BC49A4D414FC1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L20296 Genomic DNA. Translation: AAA65610.1.
    Z36120 Genomic DNA. Translation: CAA85214.1.
    BK006936 Genomic DNA. Translation: DAA07367.1.
    PIRiS38374.
    RefSeqiNP_009810.3. NM_001178599.3.

    Genome annotation databases

    EnsemblFungiiYBR251W; YBR251W; YBR251W.
    GeneIDi852553.
    KEGGisce:YBR251W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L20296 Genomic DNA. Translation: AAA65610.1 .
    Z36120 Genomic DNA. Translation: CAA85214.1 .
    BK006936 Genomic DNA. Translation: DAA07367.1 .
    PIRi S38374.
    RefSeqi NP_009810.3. NM_001178599.3.

    3D structure databases

    ProteinModelPortali P33759.
    SMRi P33759. Positions 147-294.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 32946. 57 interactions.
    DIPi DIP-2869N.
    IntActi P33759. 44 interactions.
    MINTi MINT-615779.
    STRINGi 4932.YBR251W.

    Proteomic databases

    MaxQBi P33759.
    PaxDbi P33759.
    PeptideAtlasi P33759.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YBR251W ; YBR251W ; YBR251W .
    GeneIDi 852553.
    KEGGi sce:YBR251W.

    Organism-specific databases

    CYGDi YBR251w.
    SGDi S000000455. MRPS5.

    Phylogenomic databases

    eggNOGi COG0098.
    GeneTreei ENSGT00390000001878.
    HOGENOMi HOG000247984.
    KOi K02988.
    OMAi ICECAGI.
    OrthoDBi EOG7TJ3TZ.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-29177-MONOMER.

    Miscellaneous databases

    NextBioi 971646.

    Gene expression databases

    Genevestigatori P33759.

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    3.30.230.10. 1 hit.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR000851. Ribosomal_S5.
    IPR005324. Ribosomal_S5_C.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR013810. Ribosomal_S5_N.
    IPR018192. Ribosomal_S5_N_CS.
    [Graphical view ]
    PANTHERi PTHR13718. PTHR13718. 1 hit.
    Pfami PF00333. Ribosomal_S5. 1 hit.
    PF03719. Ribosomal_S5_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    PROSITEi PS00585. RIBOSOMAL_S5. 1 hit.
    PS50881. S5_DSRBD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete sequence of a 6794 bp segment located on the right arm of chromosome II of Saccharomyces cerevisiae. Finding of a putative dUTPase in a yeast."
      Doignon F., Biteau N., Aigle M., Crouzet M.
      Yeast 9:1131-1137(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "Complete DNA sequence of yeast chromosome II."
      Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C.
      , Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.
      EMBO J. 13:5795-5809(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues."
      Saveanu C., Fromont-Racine M., Harington A., Ricard F., Namane A., Jacquier A.
      J. Biol. Chem. 276:15861-15867(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
    5. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
      Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
      Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
    6. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    7. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Strain: ATCC 76625 / YPH499.

    Entry informationi

    Entry nameiRT05_YEAST
    AccessioniPrimary (citable) accession number: P33759
    Secondary accession number(s): D6VQP7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 115 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 6680 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Ribosomal proteins
      Ribosomal proteins families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families
    3. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    4. Yeast chromosome II
      Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

    External Data

    Dasty 3