Reviewed, UniProtKB/Swiss-Prot P33739 (MS2B_DROSE)

Names and origin

Protein names

Recommended name:
    Accessory gland-specific peptide 26Ab
Alternative name(s):
    Male accessory gland secretory protein 355B

Gene names

Name:	Acp26Ab
Synonyms:	Mst26Ab, mst355B
ORF Names:	GM17991

Organism

Drosophila sechellia (Fruit fly)

Taxonomic identifier

7238 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This protein is transferred from male to female during mating and may affect egglaying and behavior after mating.
Subcellular location	Secreted › extracellular space.
Tissue specificity	Main cells of the accessory glands of males.

Ontologies

Keywords
Biological process	Behavior
Cellular component	Secreted
Domain	Signal
Gene Ontology (GO)
Biological process	mating behavior Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 90	69	Accessory gland-specific peptide 26Ab		PRO_0000021760
Natural variations
	Natural variant	21	1	A → D in strain: 11, 35, 7725 and Robertson. Ref.1
	Natural variant	26	1	S → I in strain: Praslin. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P33739-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 99CFC4EE69B7782E	FASTA	90	10,270
	10 20 30 40 50 60 MNYFAVLCIF SCICLWQFSD AAPFISVQSS SQSRSQKVMN GMLRTLYDYS VQDSVNDATG 70 80 90 HLIHTHKSNF NSDVMSPEEI ERVRQQLNMA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Polymorphism and divergence in the Mst26A male accessory gland gene region in Drosophila." Aguade M., Miyashita N., Langley C.H. Genetics 132:755-770(1992) [PubMed: 1361475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS ASP-21 AND ILE-26.
[2]	"Molecular population genetics of male accessory gland proteins in the Drosophila simulans complex." Kern A.D., Jones C.D., Begun D.J. Genetics 167:725-735(2004) [PubMed: 15238524] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 01, 07, 11, 33, 34, 35, 7725, Praslin and Robertson.
[3]	"Evolution of genes and genomes on the Drosophila phylogeny." Drosophila 12 genomes consortium Nature 450:203-218(2007) [PubMed: 17994087] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Rob3c / Tucson 14021-0248.25.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X72630 Genomic DNA. Translation: CAA51207.1. AY505193 Genomic DNA. Translation: AAS99371.1. AY505194 Genomic DNA. Translation: AAS99372.1. AY505195 Genomic DNA. Translation: AAS99373.1. AY505196 Genomic DNA. Translation: AAS99374.1. AY505197 Genomic DNA. Translation: AAS99375.1. AY505198 Genomic DNA. Translation: AAS99376.1. AY505199 Genomic DNA. Translation: AAS99377.1. AY505200 Genomic DNA. Translation: AAS99378.1. AY505201 Genomic DNA. Translation: AAS99379.1. CH480820 Genomic DNA. Translation: EDW54421.1.
RefSeq	XP_002038003.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6613535.
KEGG	dse:Dsec_GM17991.
Organism-specific databases
FlyBase	FBgn0260791. Dsec\Acp26Ab.
Phylogenomic databases
OrthoDB	EOG9XWG48.
Family and domain databases
InterPro	IPR008392. Acp26Ab. [Graphical view]
Pfam	PF05777. Acp26Ab. 1 hit. [Graphical view]
ProDom	PD015316. Acp26Ab. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

MS2B_DROSE

Accession

Primary (citable) accession number: P33739
Secondary accession number(s): B4I1L4 , Q6EAS0, Q6RCA8, Q6RCB1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 24, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project