Reviewed, UniProtKB/Swiss-Prot P33737 (MS2A_DROSI)

Names and origin

Protein names

Recommended name:
    Accessory gland-specific peptide 26Aa
Alternative name(s):
    Male accessory gland secretory protein 355A

Gene names

Name:	Acp26Aa
Synonyms:	Mst26Aa, mst355a

Organism

Drosophila simulans (Fruit fly)

Taxonomic identifier

7240 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This protein is transferred from male to female's hemolymph during mating, affecting egglaying and behavior after mating.
Subcellular location	Secreted › extracellular space.
Tissue specificity	Main cells of the accessory glands of males.
Post-translational modification	It undergoes several cleavages as it is secreted and it is further processed in the recipient female.

Ontologies

Keywords
Biological process	Behavior
Cellular component	Secreted
Domain	Signal
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	behavior Inferred from electronic annotation. Source: UniProtKB-KW mating Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 255	237	Accessory gland-specific peptide 26Aa		PRO_0000021757
Amino acid modifications
	Glycosylation	88	1	N-linked (GlcNAc...) Potential
	Glycosylation	95	1	N-linked (GlcNAc...) Potential
	Glycosylation	136	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P33737-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 24E54E2627B4ECD5	FASTA	255	28,327
	10 20 30 40 50 60 MNQILLCSQI LLLLFAVANC DGEHQLDSSM DLKSDSTKSA VLKNVAPKND ATQAEIAKDD 70 80 90 100 110 120 VALKSGKKGD YVMDIDVCTM PLDDYPINNS KSRKNSSTLP SQILTDKPNQ GSNQIALKAL 130 140 150 160 170 180 KHRLLMEQNN NLFLRNHSVS LMNEIEARKT DIIQARQLNI DLELELEALK RKLSEMNAQN 190 200 210 220 230 240 ARKPTKSCKK RPSKDIAPPA NQLQEVIVKN TYRNKYLTLL TQLAQKINYE IANVNNPATD 250 VPTGKSPSEG NPSTT

References

[1]	"Polymorphism and divergence in the Mst26A male accessory gland gene region in Drosophila." Aguade M., Miyashita N., Langley C.H. Genetics 132:755-770(1992) [PubMed: 1361475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: PC.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X70899 Genomic DNA. Translation: CAA50254.1.
PIR	S30429.
3D structure databases
ModBase	Search...
Organism-specific databases
FlyBase	FBgn0012820. Dsim\Acp26Aa.
Family and domain databases
InterPro	IPR004315. Male_ac_gland_sc. [Graphical view]
Pfam	PF03082. MAGSP. 1 hit. [Graphical view]
ProDom	PD017367. Male_ac_gland_sc. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

MS2A_DROSI

Accession

Primary (citable) accession number: P33737

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 24, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project