P33735 (MS2A_DROMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Accessory gland-specific peptide 26Aa

Alternative name(s):
Male accessory gland secretory protein 355A

Gene names

Name:	Acp26Aa
Synonyms:	Mst26Aa, mst355a

Organism

Drosophila mauritiana (Fruit fly)

Taxonomic identifier

7226 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	This protein is transferred from male to female's hemolymph during mating, affecting egglaying and behavior after mating.
Subcellular location	Secreted › extracellular space.
Tissue specificity	Main cells of the accessory glands of males.
Post-translational modification	Proteolytically cleaved as it is secreted and in the recipient female.

Ontologies

Keywords
Biological process	Behavior
Cellular component	Secreted
Domain	Signal
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	behavior Inferred from electronic annotation. Source: UniProtKB-KW mating Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 250	232	Accessory gland-specific peptide 26Aa		PRO_0000021754
Amino acid modifications
	Glycosylation	83	1	N-linked (GlcNAc...) Potential
	Glycosylation	90	1	N-linked (GlcNAc...) Potential
	Glycosylation	131	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P33735 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 833DEDEA9728BDDC	FASTA	250	27,898
	10 20 30 40 50 60 MNQILLCSQI LLLFFTVANC DGEHQLDSSV DLKSAVLKNV APKNVATQAE IVKDDVALKS 70 80 90 100 110 120 GKKGDYVMDI EVSDMPLDDY PINNSKSRKN SSTLPSPILT DKLNQGSNQI ALKALKHRLV 130 140 150 160 170 180 MEQNNNLFLR NHSVSLMNEI EARKTDIIQA RQLNIDLELE LESLKRKLSE MNVQNARKST 190 200 210 220 230 240 KSCKKRPSKD IAPPVNQLQE VIVKNTYRNK YLTLLTQLAQ KINYEIANVN NPATDVPTGK 250 SPSEGNPSTT

References

[1]	"Polymorphism and divergence in the Mst26A male accessory gland gene region in Drosophila." Aguade M., Miyashita N., Langley C.H. Genetics 132:755-770(1992) [PubMed: 1361475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Robertson C340.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X70898 Genomic DNA. Translation: CAA50252.1.
PIR	S30427.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0012494. Dmau\Acp26Aa.
Family and domain databases
InterPro	IPR004315. Male_ac_gland_sc. [Graphical view]
Pfam	PF03082. MAGSP. 1 hit. [Graphical view]
ProDom	PD017367. Male_ac_gland_sc. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

MS2A_DROMA

Accession

Primary (citable) accession number: P33735

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 24, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project