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P33696

- EXON_RHIME

UniProt

P33696 - EXON_RHIME

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Protein
UTP--glucose-1-phosphate uridylyltransferase
Gene
exoN, RB1085, SMb20960
Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathwayi

GO - Molecular functioni

  1. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. nucleotide-sugar metabolic process Source: UniProtKB-UniPathway
  2. polysaccharide biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Exopolysaccharide synthesis

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3629-MONOMER.
SMEL266834:GJF6-4518-MONOMER.
UniPathwayiUPA00215.

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene namesi
Name:exoN
Ordered Locus Names:RB1085
ORF Names:SMb20960
Encoded oniPlasmid pSymB (megaplasmid 2)0 Publication
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976: Plasmid pSymB

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 301301UTP--glucose-1-phosphate uridylyltransferase
PRO_0000201347Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266834.SM_b20960.

Structurei

3D structure databases

ProteinModelPortaliP33696.

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.

Phylogenomic databases

eggNOGiCOG1210.
KOiK00963.
OMAiYESTHAS.
OrthoDBiEOG6Z9B3V.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

P33696-1 [UniParc]FASTAAdd to Basket

« Hide

MDRVRTVRKA VIPVAGNGTR FLPATKAVPK EMLTIVDRPV VQYAVDEARQ    50
AGIEHIVFVT SRNKQVIEDH FDDAPELISS LSRSGKSAQI SELEAMLPAA 100
GSVSFTRQQA PLGLGHAVWC ARDLIGDEPF ALLLPDMVSF GARGCVAGLM 150
DLYHEVGGNV VGVEQCAPEE ASKYGIVGKG ETVRHGFSVT EMVEKPAAGK 200
APSNYYLNGR YILQPEIFSI LAHQTRGAGN EIQLTDGMLT LSQSQSFHAH 250
PYEGRTFDCG SKQGFIEANV AFALARADIG DIVFESVRDM VLSHESRIRA 300
A 301
Length:301
Mass (Da):32,584
Last modified:October 24, 2001 - v2
Checksum:i03AE86FB658E9532
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti275 – 30127ARADI…RIRAA → LVRTSAISFSNPSATWFCLT KAASGRHKRRLPAVLRDCRN KDRRRR1 Publication
Add
BLAST
Sequence conflicti275 – 30127ARADI…RIRAA → LVRTSAISFSNPSATWFCLT KAASGRHKRRLPAVLRDCRN KDRRRR1 Publication
Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L20758 Unassigned DNA. Translation: AAA16043.1.
Z22636 Genomic DNA. Translation: CAA80348.1.
AL591985 Genomic DNA. Translation: CAC49485.1.
PIRiD49349.
E95977.
RefSeqiNP_437625.1. NC_003078.1.
WP_010975921.1. NC_003078.1.

Genome annotation databases

EnsemblBacteriaiCAC49485; CAC49485; SM_b20960.
GeneIDi1237416.
KEGGisme:SM_b20960.
PATRICi23638584. VBISinMel96828_6013.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L20758 Unassigned DNA. Translation: AAA16043.1 .
Z22636 Genomic DNA. Translation: CAA80348.1 .
AL591985 Genomic DNA. Translation: CAC49485.1 .
PIRi D49349.
E95977.
RefSeqi NP_437625.1. NC_003078.1.
WP_010975921.1. NC_003078.1.

3D structure databases

ProteinModelPortali P33696.
ModBasei Search...

Protein-protein interaction databases

STRINGi 266834.SM_b20960.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC49485 ; CAC49485 ; SM_b20960 .
GeneIDi 1237416.
KEGGi sme:SM_b20960.
PATRICi 23638584. VBISinMel96828_6013.

Phylogenomic databases

eggNOGi COG1210.
KOi K00963.
OMAi YESTHAS.
OrthoDBi EOG6Z9B3V.

Enzyme and pathway databases

UniPathwayi UPA00215 .
BioCyci RETL1328306-WGS:GSTH-3629-MONOMER.
SMEL266834:GJF6-4518-MONOMER.

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
InterProi IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view ]
Pfami PF00483. NTP_transferase. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Family of glycosyl transferases needed for the synthesis of succinoglycan by Rhizobium meliloti."
    Glucksmann M.A., Reuber T.L., Walker G.C.
    J. Bacteriol. 175:7033-7044(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1021.
  2. "Genes needed for the modification, polymerization, export, and processing of succinoglycan by Rhizobium meliloti: a model for succinoglycan biosynthesis."
    Glucksmann M.A., Reuber T.L., Walker G.C.
    J. Bacteriol. 175:7045-7055(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1021.
  3. "Identification and analysis of the Rhizobium meliloti exoAMONP genes involved in exopolysaccharide biosynthesis and mapping of promoters located on the exoHKLAMONP fragment."
    Becker A., Kleickmann A., Keller M., Arnold W., Puehler A.
    Mol. Gen. Genet. 241:367-379(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: RCR2011 / SU47.
  4. "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti."
    Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J., Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.
    Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry nameiEXON_RHIME
AccessioniPrimary (citable) accession number: P33696
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: October 24, 2001
Last modified: September 3, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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