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Protein

UTP--glucose-1-phosphate uridylyltransferase

Gene

exoN

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Exopolysaccharide synthesis

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-3629-MONOMER.
SMEL266834:GJF6-4518-MONOMER.
UniPathwayiUPA00215.

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene namesi
Name:exoN
Ordered Locus Names:RB1085
ORF Names:SMb20960
Encoded oniPlasmid pSymB (megaplasmid 2)0 Publication
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976 Componenti: Plasmid pSymB

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 301301UTP--glucose-1-phosphate uridylyltransferasePRO_0000201347Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266834.SM_b20960.

Structurei

3D structure databases

ProteinModelPortaliP33696.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.Curated

Phylogenomic databases

eggNOGiCOG1210.
KOiK00963.
OMAiREWEEDV.
OrthoDBiEOG6Z9B3V.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

P33696-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRVRTVRKA VIPVAGNGTR FLPATKAVPK EMLTIVDRPV VQYAVDEARQ
60 70 80 90 100
AGIEHIVFVT SRNKQVIEDH FDDAPELISS LSRSGKSAQI SELEAMLPAA
110 120 130 140 150
GSVSFTRQQA PLGLGHAVWC ARDLIGDEPF ALLLPDMVSF GARGCVAGLM
160 170 180 190 200
DLYHEVGGNV VGVEQCAPEE ASKYGIVGKG ETVRHGFSVT EMVEKPAAGK
210 220 230 240 250
APSNYYLNGR YILQPEIFSI LAHQTRGAGN EIQLTDGMLT LSQSQSFHAH
260 270 280 290 300
PYEGRTFDCG SKQGFIEANV AFALARADIG DIVFESVRDM VLSHESRIRA

A
Length:301
Mass (Da):32,584
Last modified:October 24, 2001 - v2
Checksum:i03AE86FB658E9532
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti275 – 30127ARADI…RIRAA → LVRTSAISFSNPSATWFCLT KAASGRHKRRLPAVLRDCRN KDRRRR (PubMed:8226645).CuratedAdd
BLAST
Sequence conflicti275 – 30127ARADI…RIRAA → LVRTSAISFSNPSATWFCLT KAASGRHKRRLPAVLRDCRN KDRRRR (PubMed:8226646).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20758 Unassigned DNA. Translation: AAA16043.1.
Z22636 Genomic DNA. Translation: CAA80348.1.
AL591985 Genomic DNA. Translation: CAC49485.1.
PIRiD49349.
E95977.
RefSeqiNP_437625.1. NC_003078.1.
WP_010975921.1. NC_003078.1.

Genome annotation databases

EnsemblBacteriaiCAC49485; CAC49485; SM_b20960.
GeneIDi1237416.
KEGGisme:SM_b20960.
PATRICi23638584. VBISinMel96828_6013.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20758 Unassigned DNA. Translation: AAA16043.1.
Z22636 Genomic DNA. Translation: CAA80348.1.
AL591985 Genomic DNA. Translation: CAC49485.1.
PIRiD49349.
E95977.
RefSeqiNP_437625.1. NC_003078.1.
WP_010975921.1. NC_003078.1.

3D structure databases

ProteinModelPortaliP33696.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266834.SM_b20960.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC49485; CAC49485; SM_b20960.
GeneIDi1237416.
KEGGisme:SM_b20960.
PATRICi23638584. VBISinMel96828_6013.

Phylogenomic databases

eggNOGiCOG1210.
KOiK00963.
OMAiREWEEDV.
OrthoDBiEOG6Z9B3V.

Enzyme and pathway databases

UniPathwayiUPA00215.
BioCyciRETL1328306-WGS:GSTH-3629-MONOMER.
SMEL266834:GJF6-4518-MONOMER.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Family of glycosyl transferases needed for the synthesis of succinoglycan by Rhizobium meliloti."
    Glucksmann M.A., Reuber T.L., Walker G.C.
    J. Bacteriol. 175:7033-7044(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1021.
  2. "Genes needed for the modification, polymerization, export, and processing of succinoglycan by Rhizobium meliloti: a model for succinoglycan biosynthesis."
    Glucksmann M.A., Reuber T.L., Walker G.C.
    J. Bacteriol. 175:7045-7055(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1021.
  3. "Identification and analysis of the Rhizobium meliloti exoAMONP genes involved in exopolysaccharide biosynthesis and mapping of promoters located on the exoHKLAMONP fragment."
    Becker A., Kleickmann A., Keller M., Arnold W., Puehler A.
    Mol. Gen. Genet. 241:367-379(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: RCR2011 / SU47.
  4. "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti."
    Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J., Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.
    Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry nameiEXON_RHIME
AccessioniPrimary (citable) accession number: P33696
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: October 24, 2001
Last modified: January 7, 2015
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.