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Protein

Competence regulatory protein ComQ

Gene

comQ

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Involved in the maturation of ComX, part of a major quorum-sensing system that regulates the development of genetic competence.1 Publication

Miscellaneous

The DNA sequences encoding comQ, comX and the N-terminal two-thirds of comP show a striking polymorphism, which determines the specificity of the quorum-sensing system in the different pherotypes of Bacillus.

GO - Biological processi

Keywordsi

Biological processCompetence

Enzyme and pathway databases

BioCyciBSUB:BSU31710-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Competence regulatory protein ComQ
Gene namesi
Name:comQ
Ordered Locus Names:BSU31710
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei148 – 168HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000900141 – 299Competence regulatory protein ComQAdd BLAST299

Proteomic databases

PaxDbiP33690
PRIDEiP33690

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100017226

Structurei

3D structure databases

ProteinModelPortaliP33690
SMRiP33690
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0142 LUCA
HOGENOMiHOG000246977
KOiK02251
OMAiQIANDHH

Family and domain databases

Gene3Di1.10.600.10, 1 hit
InterProiView protein in InterPro
IPR033965 ComQ
IPR008949 Isoprenoid_synthase_dom_sf
IPR000092 Polyprenyl_synt
PfamiView protein in Pfam
PF00348 polyprenyl_synt, 1 hit
SFLDiSFLDG01211 Competence_Regulatory_Protein_, 1 hit
SUPFAMiSSF48576 SSF48576, 1 hit

Sequencei

Sequence statusi: Complete.

P33690-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEIVEQNIF NEDLSQLLYS FIDSKETFSF AESTILHYVV FGGENLDVAT
60 70 80 90 100
RLGAGIEILI LSSDIMDDLE DEDNHHALWM KINRSESLNA ALSLYTVGLT
110 120 130 140 150
SIYSLNNNPL IFKYVLKYVN EAMQGQHDDI TNKSKTEDES LEVIRLKCGS
160 170 180 190 200
LIALANVAGV LLATGEYNET VERYSYYKGI IAQISGDYYV LLSGNRSDIE
210 220 230 240 250
KNKHTLIYLY LKRLFNDASE DLLYLISHKD LYYKSLLDKE KFQEKLIKAG
260 270 280 290
VTQYISVLLE IYKQKCISAI EQLNLDKEKK ELIKECLLSY TKGDTRCKT
Length:299
Mass (Da):34,218
Last modified:July 7, 2009 - v2
Checksum:iFC8300C47D8790F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti34T → S in AAA22323 (PubMed:1715859).Curated1
Sequence conflicti34T → S in CAB07902 (PubMed:9274030).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M71283 Genomic DNA Translation: AAA22323.1
Z93932 Genomic DNA Translation: CAB07902.1
AL009126 Genomic DNA Translation: CAB15159.2
PIRiA38111
RefSeqiNP_391049.2, NC_000964.3
WP_003243039.1, NZ_JNCM01000033.1

Genome annotation databases

EnsemblBacteriaiCAB15159; CAB15159; BSU31710
GeneIDi937180
KEGGibsu:BSU31710
PATRICifig|224308.179.peg.3436

Similar proteinsi

Entry informationi

Entry nameiCOMQ_BACSU
AccessioniPrimary (citable) accession number: P33690
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: July 7, 2009
Last modified: May 23, 2018
This is version 107 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health