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P33690

- COMQ_BACSU

UniProt

P33690 - COMQ_BACSU

Protein

Competence regulatory protein ComQ

Gene

comQ

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 2 (07 Jul 2009)
      Previous versions | rss
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    Functioni

    Involved in the maturation of ComX, part of a major quorum-sensing system that regulates the development of genetic competence.1 Publication

    GO - Biological processi

    1. establishment of competence for transformation Source: UniProtKB-KW
    2. isoprenoid biosynthetic process Source: InterPro

    Keywords - Biological processi

    Competence

    Enzyme and pathway databases

    BioCyciBSUB:BSU31710-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Competence regulatory protein ComQ
    Gene namesi
    Name:comQ
    Ordered Locus Names:BSU31710
    OrganismiBacillus subtilis (strain 168)
    Taxonomic identifieri224308 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001570: Chromosome

    Organism-specific databases

    GenoListiBSU31710. [Micado]

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 299299Competence regulatory protein ComQPRO_0000090014Add
    BLAST

    Proteomic databases

    PaxDbiP33690.

    Interactioni

    Protein-protein interaction databases

    STRINGi224308.BSU31710.

    Structurei

    3D structure databases

    ProteinModelPortaliP33690.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei148 – 16821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0142.
    HOGENOMiHOG000246977.
    KOiK02251.
    OrthoDBiEOG64BQ3Q.

    Family and domain databases

    Gene3Di1.10.600.10. 1 hit.
    InterProiIPR000092. Polyprenyl_synt.
    IPR017446. Polyprenyl_synth-rel.
    IPR008949. Terpenoid_synth.
    [Graphical view]
    PANTHERiPTHR12001. PTHR12001. 1 hit.
    PfamiPF00348. polyprenyl_synt. 1 hit.
    [Graphical view]
    SUPFAMiSSF48576. SSF48576. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P33690-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKEIVEQNIF NEDLSQLLYS FIDSKETFSF AESTILHYVV FGGENLDVAT    50
    RLGAGIEILI LSSDIMDDLE DEDNHHALWM KINRSESLNA ALSLYTVGLT 100
    SIYSLNNNPL IFKYVLKYVN EAMQGQHDDI TNKSKTEDES LEVIRLKCGS 150
    LIALANVAGV LLATGEYNET VERYSYYKGI IAQISGDYYV LLSGNRSDIE 200
    KNKHTLIYLY LKRLFNDASE DLLYLISHKD LYYKSLLDKE KFQEKLIKAG 250
    VTQYISVLLE IYKQKCISAI EQLNLDKEKK ELIKECLLSY TKGDTRCKT 299
    Length:299
    Mass (Da):34,218
    Last modified:July 7, 2009 - v2
    Checksum:iFC8300C47D8790F8
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti34 – 341T → S in AAA22323. (PubMed:1715859)Curated
    Sequence conflicti34 – 341T → S in CAB07902. (PubMed:9274030)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M71283 Genomic DNA. Translation: AAA22323.1.
    Z93932 Genomic DNA. Translation: CAB07902.1.
    AL009126 Genomic DNA. Translation: CAB15159.2.
    PIRiA38111.
    RefSeqiNP_391049.2. NC_000964.3.

    Genome annotation databases

    EnsemblBacteriaiCAB15159; CAB15159; BSU31710.
    GeneIDi937180.
    KEGGibsu:BSU31710.
    PATRICi18978312. VBIBacSub10457_3319.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M71283 Genomic DNA. Translation: AAA22323.1 .
    Z93932 Genomic DNA. Translation: CAB07902.1 .
    AL009126 Genomic DNA. Translation: CAB15159.2 .
    PIRi A38111.
    RefSeqi NP_391049.2. NC_000964.3.

    3D structure databases

    ProteinModelPortali P33690.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224308.BSU31710.

    Proteomic databases

    PaxDbi P33690.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB15159 ; CAB15159 ; BSU31710 .
    GeneIDi 937180.
    KEGGi bsu:BSU31710.
    PATRICi 18978312. VBIBacSub10457_3319.

    Organism-specific databases

    GenoListi BSU31710. [Micado ]

    Phylogenomic databases

    eggNOGi COG0142.
    HOGENOMi HOG000246977.
    KOi K02251.
    OrthoDBi EOG64BQ3Q.

    Enzyme and pathway databases

    BioCyci BSUB:BSU31710-MONOMER.

    Family and domain databases

    Gene3Di 1.10.600.10. 1 hit.
    InterProi IPR000092. Polyprenyl_synt.
    IPR017446. Polyprenyl_synth-rel.
    IPR008949. Terpenoid_synth.
    [Graphical view ]
    PANTHERi PTHR12001. PTHR12001. 1 hit.
    Pfami PF00348. polyprenyl_synt. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48576. SSF48576. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and properties of comQ, a new competence regulatory gene of Bacillus subtilis."
      Weinrauch Y., Msadek T., Kunst F., Dubnau D.
      J. Bacteriol. 173:5685-5693(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168.
    2. "Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai)."
      Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M., Hilbert H., Duesterhoeft A., Pohl T.M., Weitzenegger T.
      Microbiology 143:2769-2774(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168.
    3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
      Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
      , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
      Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 168.
    4. "From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
      Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
      Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION TO 34.
    5. "Specificity and genetic polymorphism of the Bacillus competence quorum-sensing system."
      Tortosa P., Logsdon L., Kraigher B., Itoh Y., Mandic-Mulec I., Dubnau D.
      J. Bacteriol. 183:451-460(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: POLYMORPHISM IN COMX; COMQ AND COMP, FUNCTION.

    Entry informationi

    Entry nameiCOMQ_BACSU
    AccessioniPrimary (citable) accession number: P33690
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 91 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    The DNA sequences encoding comQ, comX and the N-terminal two-thirds of comP show a striking polymorphism, which determines the specificity of the quorum-sensing system in the different pherotypes of Bacillus.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Bacillus subtilis
      Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

    External Data

    Dasty 3