Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P33690 (COMQ_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Competence regulatory protein ComQ
Gene names
Name:comQ
Ordered Locus Names:BSU31710
OrganismBacillus subtilis (strain 168) [Reference proteome] [HAMAP]
Taxonomic identifier224308 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Involved in the maturation of ComX, part of a major quorum-sensing system that regulates the development of genetic competence. Ref.5

Subcellular location

Cell membrane; Single-pass membrane protein Potential.

Miscellaneous

The DNA sequences encoding comQ, comX and the N-terminal two-thirds of comP show a striking polymorphism, which determines the specificity of the quorum-sensing system in the different pherotypes of Bacillus.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 299299Competence regulatory protein ComQ
PRO_0000090014

Regions

Transmembrane148 – 16821Helical; Potential

Experimental info

Sequence conflict341T → S in AAA22323. Ref.1
Sequence conflict341T → S in CAB07902. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P33690 [UniParc].

Last modified July 7, 2009. Version 2.
Checksum: FC8300C47D8790F8

FASTA29934,218
        10         20         30         40         50         60 
MKEIVEQNIF NEDLSQLLYS FIDSKETFSF AESTILHYVV FGGENLDVAT RLGAGIEILI 

        70         80         90        100        110        120 
LSSDIMDDLE DEDNHHALWM KINRSESLNA ALSLYTVGLT SIYSLNNNPL IFKYVLKYVN 

       130        140        150        160        170        180 
EAMQGQHDDI TNKSKTEDES LEVIRLKCGS LIALANVAGV LLATGEYNET VERYSYYKGI 

       190        200        210        220        230        240 
IAQISGDYYV LLSGNRSDIE KNKHTLIYLY LKRLFNDASE DLLYLISHKD LYYKSLLDKE 

       250        260        270        280        290 
KFQEKLIKAG VTQYISVLLE IYKQKCISAI EQLNLDKEKK ELIKECLLSY TKGDTRCKT 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and properties of comQ, a new competence regulatory gene of Bacillus subtilis."
Weinrauch Y., Msadek T., Kunst F., Dubnau D.
J. Bacteriol. 173:5685-5693(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai)."
Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M., Hilbert H., Duesterhoeft A., Pohl T.M., Weitzenegger T.
Microbiology 143:2769-2774(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[4]"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION TO 34.
[5]"Specificity and genetic polymorphism of the Bacillus competence quorum-sensing system."
Tortosa P., Logsdon L., Kraigher B., Itoh Y., Mandic-Mulec I., Dubnau D.
J. Bacteriol. 183:451-460(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: POLYMORPHISM IN COMX; COMQ AND COMP, FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M71283 Genomic DNA. Translation: AAA22323.1.
Z93932 Genomic DNA. Translation: CAB07902.1.
AL009126 Genomic DNA. Translation: CAB15159.2.
PIRA38111.
RefSeqNP_391049.2. NC_000964.3.

3D structure databases

ProteinModelPortalP33690.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224308.BSU31710.

Proteomic databases

PaxDbP33690.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB15159; CAB15159; BSU31710.
GeneID937180.
KEGGbsu:BSU31710.
PATRIC18978312. VBIBacSub10457_3319.

Organism-specific databases

GenoListBSU31710. [Micado]

Phylogenomic databases

eggNOGCOG0142.
HOGENOMHOG000246977.
KOK02251.
OrthoDBEOG64BQ3Q.
ProtClustDBCLSK887806.

Enzyme and pathway databases

BioCycBSUB:BSU31710-MONOMER.

Family and domain databases

Gene3D1.10.600.10. 1 hit.
InterProIPR000092. Polyprenyl_synt.
IPR017446. Polyprenyl_synth-rel.
IPR008949. Terpenoid_synth.
[Graphical view]
PANTHERPTHR12001. PTHR12001. 1 hit.
PfamPF00348. polyprenyl_synt. 1 hit.
[Graphical view]
SUPFAMSSF48576. SSF48576. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOMQ_BACSU
AccessionPrimary (citable) accession number: P33690
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: July 7, 2009
Last modified: February 19, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList