SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P33682

- GUN1_STRHA

UniProt

P33682 - GUN1_STRHA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Endoglucanase 1

Gene
celA1
Organism
Streptomyces halstedii
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Implicated in the mechanism of induction exerted by cellobiose.

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei110 – 1101 By similarity
Active sitei149 – 1491Proton donor By similarity
Active sitei295 – 2951Nucleophile By similarity

GO - Molecular functioni

  1. cellulase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH6. Glycoside Hydrolase Family 6.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase 1 (EC:3.2.1.4)
Alternative name(s):
CEL1
CMCase I
Cellulase I
Endo-1,4-beta-glucanase 1
Gene namesi
Name:celA1
OrganismiStreptomyces halstedii
Taxonomic identifieri1944 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 27271 PublicationAdd
BLAST
Chaini28 – 321294Endoglucanase 1PRO_0000007906Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi112 ↔ 156 By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP33682.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.40. 1 hit.
InterProiIPR016288. Beta_cellobiohydrolase.
IPR001524. Glyco_hydro_6_CS.
[Graphical view]
PfamiPF01341. Glyco_hydro_6. 1 hit.
[Graphical view]
PIRSFiPIRSF001100. Beta_cellobiohydrolase. 1 hit.
PRINTSiPR00733. GLHYDRLASE6.
SUPFAMiSSF51989. SSF51989. 1 hit.
PROSITEiPS00656. GLYCOSYL_HYDROL_F6_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33682-1 [UniParc]FASTAAdd to Basket

« Hide

MSRKLRTLMA ALCALPLAFA AAPPAHAADP TTMTNGFYAD PDSSASRWAA    50
ANPGDGRAAA INASIANTPM ARWFGSWSGA IGTAAGAYAG AADGRDKLPI 100
LVAYNIYNRD YCGGHSAGGA ASPSAYADWI ARFAGGIAAR PAVVILEPDS 150
LGDYGCMNPA QIDEREAMLT NALVQFNRQA PNTWVYMDAG NPRWADAATM 200
ARRLHEAGLR QAHGFSLNVS NYITTAENTA YGNAVNNELA ARYGYTKPFV 250
VDTSRNGNGS NGEWCNPSGR RIGTPTRTGG GAEMLLWIKT PGESDGNCGV 300
GSGSTAGQFL PEVAYKMIYG Y 321
Length:321
Mass (Da):33,695
Last modified:June 1, 1994 - v2
Checksum:iDC5E39EF3CCD114C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z12157 Genomic DNA. Translation: CAA78145.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z12157 Genomic DNA. Translation: CAA78145.1 .

3D structure databases

ProteinModelPortali P33682.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH6. Glycoside Hydrolase Family 6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.20.20.40. 1 hit.
InterProi IPR016288. Beta_cellobiohydrolase.
IPR001524. Glyco_hydro_6_CS.
[Graphical view ]
Pfami PF01341. Glyco_hydro_6. 1 hit.
[Graphical view ]
PIRSFi PIRSF001100. Beta_cellobiohydrolase. 1 hit.
PRINTSi PR00733. GLHYDRLASE6.
SUPFAMi SSF51989. SSF51989. 1 hit.
PROSITEi PS00656. GLYCOSYL_HYDROL_F6_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and nucleotide sequence of celA1, and endo-beta-1,4-glucanase-encoding gene from Streptomyces halstedii JM8."
    Fernandez-Abalos J.M., Sanchez P., Coll-Fresno P.M., Villanueva J.R., Perez P., Santamaria R.I.
    J. Bacteriol. 174:6368-6376(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 28-33.
    Strain: JM8 / CECT3310.

Entry informationi

Entry nameiGUN1_STRHA
AccessioniPrimary (citable) accession number: P33682
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: June 1, 1994
Last modified: February 19, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

It is uncertain whether Met-1 or Met-9 is the initiator.

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi