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Protein

Zeamatin

Gene

Zlp

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Has antifungal activity. Inhibits Candida albicans and Trichoderma reesei; marginal inhibition observed against Alternaria solani and Neurospora crassa.

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Fungicide

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Zeamatin
Gene namesi
Name:Zlp
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Chromosome 7

Organism-specific databases

MaizeGDBi78797.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 20201 PublicationAdd
BLAST
Chaini21 – 227207ZeamatinPRO_0000034047Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi30 ↔ 226
Disulfide bondi72 ↔ 82
Disulfide bondi87 ↔ 93
Disulfide bondi139 ↔ 215
Disulfide bondi145 ↔ 198
Disulfide bondi153 ↔ 163
Disulfide bondi167 ↔ 176
Disulfide bondi177 ↔ 185

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP33679.

Expressioni

Gene expression databases

ExpressionAtlasiP33679. baseline and differential.
GenevisibleiP33679. ZM.

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G374971_P01.

Structurei

Secondary structure

1
227
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi23 – 286Combined sources
Beta strandi30 – 323Combined sources
Beta strandi34 – 396Combined sources
Turni40 – 423Combined sources
Beta strandi43 – 475Combined sources
Beta strandi52 – 565Combined sources
Beta strandi63 – 697Combined sources
Beta strandi71 – 744Combined sources
Beta strandi78 – 858Combined sources
Beta strandi90 – 923Combined sources
Beta strandi103 – 1108Combined sources
Helixi111 – 1133Combined sources
Beta strandi114 – 1207Combined sources
Beta strandi129 – 1335Combined sources
Beta strandi135 – 1384Combined sources
Turni149 – 1524Combined sources
Helixi155 – 1573Combined sources
Helixi166 – 1705Combined sources
Helixi173 – 1764Combined sources
Helixi179 – 1846Combined sources
Helixi189 – 1979Combined sources
Beta strandi201 – 2044Combined sources
Helixi208 – 2114Combined sources
Beta strandi213 – 2164Combined sources
Beta strandi221 – 2255Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1DU5X-ray2.50A/B22-227[»]
ProteinModelPortaliP33679.
SMRiP33679. Positions 22-227.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP33679.

Family & Domainsi

Sequence similaritiesi

Belongs to the thaumatin family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IIHC. Eukaryota.
ENOG410YD4X. LUCA.
OMAiTNYSRYF.

Family and domain databases

Gene3Di2.60.110.10. 1 hit.
InterProiIPR001938. Thaumatin.
IPR017949. Thaumatin_CS.
[Graphical view]
PANTHERiPTHR31048. PTHR31048. 1 hit.
PfamiPF00314. Thaumatin. 1 hit.
[Graphical view]
PIRSFiPIRSF002703. Thaumatin. 1 hit.
PRINTSiPR00347. THAUMATIN.
SMARTiSM00205. THN. 1 hit.
[Graphical view]
SUPFAMiSSF49870. SSF49870. 1 hit.
PROSITEiPS00316. THAUMATIN_1. 1 hit.
PS51367. THAUMATIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSVAIVGI FVALLAVAGE AAVFTVVNQC PFTVWAASVP VGGGRQLNRG
60 70 80 90 100
ESWRITAPAG TTAARIWART GCKFDASGRG SCRTGDCGGV LQCTGYGRAP
110 120 130 140 150
NTLAEYALKQ FNNLDFFDIS LIDGFNVPMS FLPDGGSGCS RGPRCAVDVN
160 170 180 190 200
ARCPAELRQD GVCNNACPVF KKDEYCCVGS AANDCHPTNY SRYFKGQCPD
210 220
AYSYPKDDAT STFTCPAGTN YKVVFCP
Length:227
Mass (Da):23,999
Last modified:October 1, 1996 - v2
Checksum:i33ABFE0B1EB781E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U06831 mRNA. Translation: AAA92882.1.
PIRiJS0646.
T02075.
RefSeqiNP_001105356.1. NM_001111886.1.
UniGeneiZm.281.

Genome annotation databases

EnsemblPlantsiGRMZM2G374971_T01; GRMZM2G374971_P01; GRMZM2G374971.
GeneIDi542299.
GrameneiGRMZM2G374971_T01; GRMZM2G374971_P01; GRMZM2G374971.
KEGGizma:542299.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U06831 mRNA. Translation: AAA92882.1.
PIRiJS0646.
T02075.
RefSeqiNP_001105356.1. NM_001111886.1.
UniGeneiZm.281.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1DU5X-ray2.50A/B22-227[»]
ProteinModelPortaliP33679.
SMRiP33679. Positions 22-227.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4577.GRMZM2G374971_P01.

Proteomic databases

PaxDbiP33679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiGRMZM2G374971_T01; GRMZM2G374971_P01; GRMZM2G374971.
GeneIDi542299.
GrameneiGRMZM2G374971_T01; GRMZM2G374971_P01; GRMZM2G374971.
KEGGizma:542299.

Organism-specific databases

MaizeGDBi78797.

Phylogenomic databases

eggNOGiENOG410IIHC. Eukaryota.
ENOG410YD4X. LUCA.
OMAiTNYSRYF.

Miscellaneous databases

EvolutionaryTraceiP33679.

Gene expression databases

ExpressionAtlasiP33679. baseline and differential.
GenevisibleiP33679. ZM.

Family and domain databases

Gene3Di2.60.110.10. 1 hit.
InterProiIPR001938. Thaumatin.
IPR017949. Thaumatin_CS.
[Graphical view]
PANTHERiPTHR31048. PTHR31048. 1 hit.
PfamiPF00314. Thaumatin. 1 hit.
[Graphical view]
PIRSFiPIRSF002703. Thaumatin. 1 hit.
PRINTSiPR00347. THAUMATIN.
SMARTiSM00205. THN. 1 hit.
[Graphical view]
SUPFAMiSSF49870. SSF49870. 1 hit.
PROSITEiPS00316. THAUMATIN_1. 1 hit.
PS51367. THAUMATIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Characterization and expression of an antifungal zeamatin-like protein (Zlp) gene from Zea mays."
    Malehorn D.E., Borgmeyer J.R., Smith C.E., Shah D.M.
    Plant Physiol. 106:1471-1481(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. B73.
    Tissue: Seed.
  2. "Zeamatin, an antifungal protein from maize with membrane-permeabilizing activity."
    Roberts W.K., Selitrennikoff C.P.
    J. Gen. Microbiol. 136:1771-1778(1990)
    Cited for: PROTEIN SEQUENCE OF 21-48.
  3. "The crystal structure of the antifungal protein zeamatin, a member of the thaumatin-like, PR-5 protein family."
    Batalia M.A., Monzingo A.F., Ernst S., Roberts W., Robertus J.D.
    Nat. Struct. Biol. 3:19-23(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS).

Entry informationi

Entry nameiZEAM_MAIZE
AccessioniPrimary (citable) accession number: P33679
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: October 1, 1996
Last modified: May 11, 2016
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.