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Protein

HTH-type transcriptional regulator BlaA

Gene

blaA

Organism
Streptomyces cacaoi
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Positive regulator of the expression of the gene (blaB) for beta-lactamase. It binds to the blaL-blaA intercistronic region.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi19 – 38H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator BlaA
Alternative name(s):
Beta-lactamase regulatory protein BlaA
Gene namesi
Name:blaA
OrganismiStreptomyces cacaoi
Taxonomic identifieri1898 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001055961 – 326HTH-type transcriptional regulator BlaAAdd BLAST326

Structurei

3D structure databases

ProteinModelPortaliP33651.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 59HTH lysR-typePROSITE-ProRule annotationAdd BLAST59

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000847. Tscrpt_reg_HTH_LysR.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00126. HTH_1. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS50931. HTH_LYSR. 1 hit.

Sequencei

Sequence statusi: Complete.

P33651-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVVNACRAF VKVSERGSFT VGAAAAQMSQ SVASRRVAAL EKHFGERLFD
60 70 80 90 100
RASRRPSLTP FGRDMLPAAR RLVRVADVLE DEARAARSRP MRLAVPASCT
110 120 130 140 150
TAELARLVAD SRERDIRLDV RTAGPEQRAE LVRTQEVRAG LLAVPPDQAL
160 170 180 190 200
WAVPLGLAGA DEPQTRRVFV ESLRLRRGEP GPARCIRVQP EDDVPHIQGR
210 220 230 240 250
LARLRDAVGL RPAQLSVAPD LTSATADVLS SDDLLLCSPA QAAELGLYWR
260 270 280 290 300
PVGELRLARG YVLDAAVEAD AERLRGRLAP YLARALGATA DHGPDPATGA
310 320
GPGADAGTEP GARAEPGAPE EGAQAC
Length:326
Mass (Da):34,756
Last modified:February 1, 1994 - v1
Checksum:i3A5A6319DB7CA88D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D00937 Genomic DNA. Translation: BAA00773.1.
X63780 Genomic DNA. Translation: CAA45314.1.
PIRiA41855.

Similar proteinsi

Entry informationi

Entry nameiBLAA_STRCI
AccessioniPrimary (citable) accession number: P33651
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: January 31, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program