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Reviewed, UniProtKB/Swiss-Prot P33647 (CHPB_ECOLI)

Last modified February 9, 2010. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    PemK-like protein 2
Gene names
Name: chpB
Synonyms: chpBK, yjfE
Ordered Locus Names: b4225, JW4184
OrganismEscherichia coli (strain K12) [Complete proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length116 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Function

May be involved in the regulation of cell growth. It acts as a growth inhibitor. Both chpS and chpB bind to the promoter region of the chpSB operon to autoregulate their synthesis.

Sequence similarities

Belongs to the pemK family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 116116PemK-like protein 2
PRO_0000201899

Sequences

Sequence LengthMass (Da)Tools
P33647-1 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 4D641F3E302FCF58

FASTA11612,492
        10         20         30         40         50         60 
MVKKSEFERG DIVLVGFDPA SGHEQQGAGR PALVLSVQAF NQLGMTLVAP ITQGGNFARY 

        70         80         90        100        110 
AGFSVPLHCE EGDVHGVVLV NQVRMMDLHA RLAKRIGLAA DEVVEEALLR LQAVVE 

« Hide

References

« Hide 'large scale' references
[1]"chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100."
Masuda Y., Miyakawa K., Nishimura Y., Ohtsubo E.
J. Bacteriol. 175:6850-6856(1993) [PubMed: 8226627] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K12.
[2]"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes."
Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.
Nucleic Acids Res. 23:2105-2119(1995) [PubMed: 7610040] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"Structural analysis of the ileR locus of Escherichia coli K12."
Weiss D.L., Johnson D.I., Weith H.L., Somerville R.L.
J. Biol. Chem. 261:9966-9971(1986) [PubMed: 3525538] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30.
Strain: K12.
[6]"Cloning and characterization of the gene encoding inorganic pyrophosphatase of Escherichia coli K-12."
Lahti R., Pitkaeranta T., Valve E., Ilta I., Kukko-Kalske E., Heinonen J.
J. Bacteriol. 170:5901-5907(1988) [PubMed: 2848015] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 20-116.
Strain: K12.
[7]"Mapping and disruption of the chpB locus in Escherichia coli."
Masuda Y., Ohtsubo E.
J. Bacteriol. 176:5861-5863(1994) [PubMed: 8083180] [Abstract]
Cited for: GENE MAPPING.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D16451 Genomic DNA. Translation: BAA03920.1.
M14018 Genomic DNA. No translation available.
U14003 Genomic DNA. Translation: AAA97122.1.
U00096 Genomic DNA. Translation: AAC77182.1.
M23550 Unassigned DNA. No translation available.
AP009048 Genomic DNA. Translation: BAE78226.1.
PIRD49339.
RefSeqAP_004725.1.
NP_418646.1.

3D structure databases

SMRP33647. Positions 7-114.
ModBaseSearch...

Protein-protein interaction databases

STRINGP33647.

Genome annotation databases

GeneID948747.
GenomeReviewsGene locus JW4184 in contig AP009048_GR.
Gene locus b4225 in contig U00096_GR.
KEGGecj:JW4184.
eco:b4225.

Organism-specific databases

EchoBASEEB2020.
EcoGeneEG12096. chpB.
CMRSearch...

Phylogenomic databases

eggNOGCOG2337.
HOGENOMHBG571026.
OMAGAKRVES.

Enzyme and pathway databases

BioCycEcoCyc:EG12096-MONOMER.
ECOL168927:B4225-MONOMER.

Gene expression databases

GenevestigatorP33647.

Family and domain databases

InterProIPR003477. PemK.
IPR011067. Plasmid_toxin/cell-grow_inhib.
[Graphical view]
Gene3DG3DSA:2.30.30.110. CcdB. 1 hit.
PfamPF02452. PemK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHPB_ECOLI
AccessionPrimary (citable) accession number: P33647
Secondary accession number(s): Q2M680
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: February 9, 2010
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents