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Protein

Laccase domain protein YfiH

Gene

yfiH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • copper ion binding Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG12097-MONOMER.
ECOL316407:JW2575-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase domain protein YfiH
Gene namesi
Name:yfiH
Ordered Locus Names:b2593, JW2575
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12097. yfiH.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 243243Laccase domain protein YfiHPRO_0000163163Add
BLAST

Proteomic databases

EPDiP33644.
PaxDbiP33644.

Interactioni

Protein-protein interaction databases

BioGridi4260619. 639 interactions.
IntActiP33644. 8 interactions.
STRINGi511145.b2593.

Structurei

Secondary structure

1
243
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi15 – 206Combined sources
Beta strandi38 – 414Combined sources
Helixi44 – 5714Combined sources
Beta strandi75 – 773Combined sources
Beta strandi89 – 935Combined sources
Beta strandi99 – 11416Combined sources
Beta strandi120 – 1256Combined sources
Helixi127 – 1326Combined sources
Helixi134 – 1407Combined sources
Helixi146 – 1483Combined sources
Beta strandi149 – 1535Combined sources
Turni159 – 1613Combined sources
Helixi166 – 17510Combined sources
Helixi177 – 1826Combined sources
Beta strandi183 – 1864Combined sources
Beta strandi189 – 1924Combined sources
Helixi194 – 20411Combined sources
Beta strandi209 – 2124Combined sources
Turni217 – 2193Combined sources
Turni221 – 2233Combined sources
Helixi227 – 2304Combined sources
Beta strandi236 – 2427Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Z9TX-ray1.54A1-243[»]
ProteinModelPortaliP33644.
SMRiP33644. Positions 2-243.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP33644.

Family & Domainsi

Sequence similaritiesi

Belongs to the LACC1 family.Curated

Phylogenomic databases

eggNOGiENOG4105DBW. Bacteria.
COG1496. LUCA.
HOGENOMiHOG000242994.
InParanoidiP33644.
KOiK05810.
OMAiVVMTADC.
PhylomeDBiP33644.

Family and domain databases

Gene3Di3.60.140.10. 1 hit.
InterProiIPR003730. Cu_polyphenol_OxRdtase_Laccase.
IPR011324. Cytotoxic_necrot_fac-like_cat.
[Graphical view]
PfamiPF02578. Cu-oxidase_4. 1 hit.
[Graphical view]
SUPFAMiSSF64438. SSF64438. 1 hit.
TIGRFAMsiTIGR00726. TIGR00726. 1 hit.

Sequencei

Sequence statusi: Complete.

P33644-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLIVPQWP QPKGVAACSS TRIGGVSLPP YDSLNLGAHC GDNPDHVEEN
60 70 80 90 100
RKRLFAAGNL PSKPVWLEQV HGKDVLKLTG EPYASKRADA SYSNTPGTVC
110 120 130 140 150
AVMTADCLPV LFCNRAGTEV AAAHAGWRGL CAGVLEETVS CFADNPENIL
160 170 180 190 200
AWLGPAIGPR AFEVGGEVRE AFMAVDAKAS AAFIQHGDKY LADIYQLARQ
210 220 230 240
RLANVGVEQI FGGDRCTYTE NETFFSYRRD KTTGRMASFI WLI
Length:243
Mass (Da):26,339
Last modified:February 1, 1994 - v1
Checksum:iD21267A5374EAC43
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti27 – 271S → T in AAA92958 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50134 Genomic DNA. Translation: AAA92958.1.
X57620 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC75642.1.
AP009048 Genomic DNA. Translation: BAA16477.1.
M29364 Genomic DNA. Translation: AAA24421.1. Sequence problems.
PIRiD65037.
RefSeqiNP_417084.1. NC_000913.3.
WP_000040169.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75642; AAC75642; b2593.
BAA16477; BAA16477; BAA16477.
GeneIDi947089.
KEGGiecj:JW2575.
eco:b2593.
PATRICi32120589. VBIEscCol129921_2693.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U50134 Genomic DNA. Translation: AAA92958.1.
X57620 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC75642.1.
AP009048 Genomic DNA. Translation: BAA16477.1.
M29364 Genomic DNA. Translation: AAA24421.1. Sequence problems.
PIRiD65037.
RefSeqiNP_417084.1. NC_000913.3.
WP_000040169.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Z9TX-ray1.54A1-243[»]
ProteinModelPortaliP33644.
SMRiP33644. Positions 2-243.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260619. 639 interactions.
IntActiP33644. 8 interactions.
STRINGi511145.b2593.

Proteomic databases

EPDiP33644.
PaxDbiP33644.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75642; AAC75642; b2593.
BAA16477; BAA16477; BAA16477.
GeneIDi947089.
KEGGiecj:JW2575.
eco:b2593.
PATRICi32120589. VBIEscCol129921_2693.

Organism-specific databases

EchoBASEiEB2021.
EcoGeneiEG12097. yfiH.

Phylogenomic databases

eggNOGiENOG4105DBW. Bacteria.
COG1496. LUCA.
HOGENOMiHOG000242994.
InParanoidiP33644.
KOiK05810.
OMAiVVMTADC.
PhylomeDBiP33644.

Enzyme and pathway databases

BioCyciEcoCyc:EG12097-MONOMER.
ECOL316407:JW2575-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP33644.
PROiP33644.

Family and domain databases

Gene3Di3.60.140.10. 1 hit.
InterProiIPR003730. Cu_polyphenol_OxRdtase_Laccase.
IPR011324. Cytotoxic_necrot_fac-like_cat.
[Graphical view]
PfamiPF02578. Cu-oxidase_4. 1 hit.
[Graphical view]
SUPFAMiSSF64438. SSF64438. 1 hit.
TIGRFAMsiTIGR00726. TIGR00726. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYFIH_ECOLI
AccessioniPrimary (citable) accession number: P33644
Secondary accession number(s): Q46989
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 7, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.