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Protein

Uncharacterized HTH-type transcriptional regulator YfiE

Gene

yfiE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi18 – 3720H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG11785-MONOMER.
ECOL316407:JW2561-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YfiE
Gene namesi
Name:yfiE
Ordered Locus Names:b2577, JW2561
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11785. yfiE.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 293293Uncharacterized HTH-type transcriptional regulator YfiEPRO_0000105793Add
BLAST

Proteomic databases

PaxDbiP33634.

Interactioni

Protein-protein interaction databases

BioGridi4261636. 18 interactions.
IntActiP33634. 3 interactions.
STRINGi511145.b2577.

Structurei

3D structure databases

ProteinModelPortaliP33634.
SMRiP33634. Positions 1-290.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 5858HTH lysR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG41090KR. Bacteria.
ENOG4111QDM. LUCA.
HOGENOMiHOG000233521.
InParanoidiP33634.
OMAiMRVFMQC.
OrthoDBiEOG67MF25.
PhylomeDBiP33634.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P33634-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLRRFITLK TVVEEGSFLR ASQKLCCTQS TVTFHIQQLE QEFSVQLFEK
60 70 80 90 100
IGRRMCLTRE GKKLLPHIYE LTRVMDTLRE AAKKESDPDG ELRVVSGETL
110 120 130 140 150
LSYRMPQVLQ RFRQRAPKVR LSLQSLNCYV IRDALLNDEA DVGVFYRVGN
160 170 180 190 200
DDALNRRELG EQSLVLVASP QIADVDFTEP GRHNACSFII NEPQCVFRQI
210 220 230 240 250
FESTLRQRRI TVENTIELIS IESIKRCVAA NIGVSYLPRF AVAKELECGE
260 270 280 290
LIELPFGEQS QTITAMCAHH AGKAVSPAMH TFIQCVEESF VAG
Length:293
Mass (Da):33,243
Last modified:November 1, 1997 - v2
Checksum:i1C54C96647799632
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti209 – 29385RITVE…SFVAG → DHGGKHH in D13169 (Ref. 1) CuratedAdd
BLAST
Sequence conflicti209 – 29385RITVE…SFVAG → DHGGKHH in D64044 (Ref. 2) CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13169 Genomic DNA. No translation available.
D64044 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC75630.2.
AP009048 Genomic DNA. Translation: BAA20920.2.
PIRiH65035.
RefSeqiNP_417072.4. NC_000913.3.
WP_001300638.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75630; AAC75630; b2577.
BAA20920; BAA20920; BAA20920.
GeneIDi947064.
KEGGiecj:JW2561.
eco:b2577.
PATRICi32120555. VBIEscCol129921_2680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13169 Genomic DNA. No translation available.
D64044 Genomic DNA. No translation available.
U00096 Genomic DNA. Translation: AAC75630.2.
AP009048 Genomic DNA. Translation: BAA20920.2.
PIRiH65035.
RefSeqiNP_417072.4. NC_000913.3.
WP_001300638.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP33634.
SMRiP33634. Positions 1-290.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261636. 18 interactions.
IntActiP33634. 3 interactions.
STRINGi511145.b2577.

Proteomic databases

PaxDbiP33634.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75630; AAC75630; b2577.
BAA20920; BAA20920; BAA20920.
GeneIDi947064.
KEGGiecj:JW2561.
eco:b2577.
PATRICi32120555. VBIEscCol129921_2680.

Organism-specific databases

EchoBASEiEB1733.
EcoGeneiEG11785. yfiE.

Phylogenomic databases

eggNOGiENOG41090KR. Bacteria.
ENOG4111QDM. LUCA.
HOGENOMiHOG000233521.
InParanoidiP33634.
OMAiMRVFMQC.
OrthoDBiEOG67MF25.
PhylomeDBiP33634.

Enzyme and pathway databases

BioCyciEcoCyc:EG11785-MONOMER.
ECOL316407:JW2561-MONOMER.

Miscellaneous databases

PROiP33634.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Non-ribosomal proteins affecting the assembly of ribosomes in Escherichia coli."
    Nashimoto H.
    (In) Nierhaus K.H. (eds.); The translational apparatus, pp.185-195, Plenum Press, New York (1993)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Nashimoto H., Saito N.
    Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-208.
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYFIE_ECOLI
AccessioniPrimary (citable) accession number: P33634
Secondary accession number(s): P76592, P76998
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: November 1, 1997
Last modified: January 20, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.