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P33559 (XYNA_ASPKW) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endo-1,4-beta-xylanase A

Short name=Xylanase A
EC=3.2.1.8
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase A
Gene names
Name:xynA
ORF Names:AKAW_10666
OrganismAspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi) [Complete proteome]
Taxonomic identifier1033177 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathway

Glycan degradation; xylan degradation.

Subcellular location

Secreted.

Sequence similarities

Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Sequence caution

The sequence GAA92552.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Polysaccharide degradation
Xylan degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMDisulfide bond
Pyrrolidone carboxylic acid
   Technical termComplete proteome
Direct protein sequencing
Gene Ontology (GO)
   Biological_processxylan catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionendo-1,4-beta-xylanase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Ref.1
Chain26 – 327302Endo-1,4-beta-xylanase A
PRO_0000007965

Sites

Active site1571Proton donor By similarity
Active site2631Nucleophile By similarity

Amino acid modifications

Modified residue261Pyrrolidone carboxylic acid
Disulfide bond281 ↔ 287 By similarity

Experimental info

Sequence conflict331T → S in BAA03575. Ref.1
Sequence conflict331T → S AA sequence Ref.1
Sequence conflict611I → V in BAA03575. Ref.1
Sequence conflict1761E → D in BAA03575. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P33559 [UniParc].

Last modified March 21, 2012. Version 2.
Checksum: 93B3D04F22F5D4FF

FASTA32735,480
        10         20         30         40         50         60 
MVQIKAAALA MLFASHVLSE PIEPRQASVS IDTKFKAHGK KYLGNIGDQY TLTKNSKTPA 

        70         80         90        100        110        120 
IIKADFGALT PENSMKWDAT EPSRGQFSFS GSDYLVNFAQ SNNKLIRGHT LVWHSQLPSW 

       130        140        150        160        170        180 
VQAITDKNTL IEVMKNHITT VMQHYKGKIY AWDVVNEIFN EDGSLRDSVF YKVIGEDYVR 

       190        200        210        220        230        240 
IAFETARAAD PNAKLYINDY NLDSASYPKL AGMVSHVKKW IEAGIPIDGI GSQTHLSAGG 

       250        260        270        280        290        300 
GAGISGALNA LAGAGTKEIA VTELDIAGAS STDYVEVVEA CLDQPKCIGI TVWGVADPDS 

       310        320 
WRSSSTPLLF DSNYNPKPAY TAIANAL 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and sequencing of the xynA gene encoding xylanase A of Aspergillus kawachii."
Ito K., Ikemasu T., Ishikawa T.
Biosci. Biotechnol. Biochem. 56:906-912(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 26-33; 41-54; 63-76 AND 76-100.
Strain: NBRC 4308.
[2]"Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used for brewing the Japanese distilled spirit shochu."
Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H., Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.
Eukaryot. Cell 10:1586-1587(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NBRC 4308.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D14847 Genomic DNA. Translation: BAA03575.1.
DF126496 Genomic DNA. Translation: GAA92552.1. Sequence problems.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH10. Glycoside Hydrolase Family 10.
mycoCLAPXYN10A_ASPKA.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OrthoDBEOG7GJ6PM.

Enzyme and pathway databases

UniPathwayUPA00114.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSPR00134. GLHYDRLASE10.
SMARTSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYNA_ASPKW
AccessionPrimary (citable) accession number: P33559
Secondary accession number(s): G7Y054
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: March 21, 2012
Last modified: November 13, 2013
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries