Reviewed, UniProtKB/Swiss-Prot P33559 (XYNA_ASPKA)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase A
      Short name=Xylanase A
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase A

Gene names

Name:

xynA

Organism

Aspergillus kawachi (Aspergillus awamori var. kawachi)

Taxonomic identifier

40384 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Disulfide bond Pyrrolidone carboxylic acid
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Ref.1
	Chain	26 – 327	302	Endo-1,4-beta-xylanase A		PRO_0000007965
Sites
	Active site	157	1	Proton donor By similarity
	Active site	263	1	Nucleophile By similarity
Amino acid modifications
	Modified residue	26	1	Pyrrolidone carboxylic acid
	Disulfide bond	281 ↔ 287		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P33559-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: ECD572EA169A9B20	FASTA	327	35,438
	10 20 30 40 50 60 MVQIKAAALA MLFASHVLSE PIEPRQASVS IDSKFKAHGK KYLGNIGDQY TLTKNSKTPA 70 80 90 100 110 120 VIKADFGALT PENSMKWDAT EPSRGQFSFS GSDYLVNFAQ SNNKLIRGHT LVWHSQLPSW 130 140 150 160 170 180 VQAITDKNTL IEVMKNHITT VMQHYKGKIY AWDVVNEIFN EDGSLRDSVF YKVIGDDYVR 190 200 210 220 230 240 IAFETARAAD PNAKLYINDY NLDSASYPKL AGMVSHVKKW IEAGIPIDGI GSQTHLSAGG 250 260 270 280 290 300 GAGISGALNA LAGAGTKEIA VTELDIAGAS STDYVEVVEA CLDQPKCIGI TVWGVADPDS 310 320 WRSSSTPLLF DSNYNPKPAY TAIANAL

References

[1]

"Cloning and sequencing of the xynA gene encoding xylanase A of Aspergillus kawachii." Ito K., Ikemasu T., Ishikawa T. Biosci. Biotechnol. Biochem. 56:906-912(1992) [PubMed: 1368254] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 26-33; 41-54; 63-76 AND 76-100. Strain: IFO 4308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D14847 Genomic DNA. Translation: BAA03575.1.
3D structure databases
SMR	P33559. Positions 26-327.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Enzyme and pathway databases
BRENDA	3.2.1.8. 279687.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR017853. Glyco_hydro_catalytic_core. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNA_ASPKA

Accession

Primary (citable) accession number: P33559

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 24, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)