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Reviewed, UniProtKB/Swiss-Prot P33557 (XYN3_ASPKA)

Last modified June 16, 2009. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Endo-1,4-beta-xylanase 3
      Short name=Xylanase 3
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase 3
    Xylanase C
Gene names
Name: xynC
OrganismAspergillus kawachi (Aspergillus awamori var. kawachi)
Taxonomic identifier40384 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

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Protein attributes

Sequence length211 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathway

Glycan degradation; xylan degradation.

Subcellular location

Secreted.

Sequence similarities

Belongs to the glycosyl hydrolase 11 (cellulase G) family.

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Ontologies

Keywords
   Biological processXylan degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMDisulfide bond
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Biological processxylan catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionendo-1,4-beta-xylanase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Ref.1
Chain28 – 211184Endo-1,4-beta-xylanase 3
PRO_0000007991

Sites

Active site1061Nucleophile By similarity
Active site1971Proton donor

Amino acid modifications

Disulfide bond119 ↔ 138

Secondary structure

1 ............................ 211
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
P33557-1 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 68BFEA90EBFFFFCC

FASTA21122,560
        10         20         30         40         50         60 
MKVTAASAGL LGHAFAAPVP QPVLVSRSAG INYVQNYNGN LADFTYDESA GTFSMYWEDG 

        70         80         90        100        110        120 
VSSDFVVGLG WTTGSSNAIS YSAEYSASGS SSYLAVYGWV NYPQAEYYIV EDYGDYNPCS 

       130        140        150        160        170        180 
SATSLGTVYS DGSTYQVCTD TRTNEPSITG TSTFTQYFSV RESTRTSGTV TVANHFNFWA 

       190        200        210 
QHGFGNSDFN YQVMAVEAWS GAGSASVTIS S

« Hide

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References

[1]"Cloning and sequencing of the xynC gene encoding acid xylanase of Aspergillus kawachii."
Ito K., Iwashita K., Iwano K.
Biosci. Biotechnol. Biochem. 56:1338-1340(1992) [PubMed: 1368843] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 28-34.
Strain: IFO 4308.
[2]"Crystallographic and mutational analyses of an extremely acidophilic and acid-stable xylanase: biased distribution of acidic residues and importance of Asp-37 for catalysis at low pH."
Fushinobu S., Ito K., Konno M., Wakagi T., Matsuzawa H.
Protein Eng. 11:1121-1128(1998) [PubMed: 9930661] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 29-210.
Strain: IFO 4308.

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Cross-references

Sequence databases

S45138 Genomic DNA. Translation: AAC60542.1.
D14848 Genomic DNA. Translation: BAA03576.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
1BK1X-ray2.00A28-211[»]
ModBaseSearch...

Protein family/group databases

CAZyGH11. Glycoside Hydrolase Family 11.

Enzyme and pathway databases

BRENDA3.2.1.8. 279687.

Family and domain databases

InterProIPR001137. Glyco_hydro_11.
IPR013319. Glyco_hydro_11/12_cat.
IPR018208. Glyco_hydro_11_AS.
[Graphical view]
Gene3DG3DSA:2.60.120.180. Glyco_hydro_11/12_cat. 1 hit.
PfamPF00457. Glyco_hydro_11. 1 hit.
[Graphical view]
PRINTSPR00911. GLHYDRLASE11.
PROSITEPS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYN3_ASPKA
AccessionPrimary (citable) accession number: P33557
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: June 16, 2009
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents