SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P33557

- XYN3_ASPKW

UniProt

P33557 - XYN3_ASPKW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Endo-1,4-beta-xylanase 3

Gene
xynC, AKAW_07136
Organism
Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei106 – 1061Nucleophile By similarity
Active sitei197 – 1971Proton donor

GO - Molecular functioni

  1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC

GO - Biological processi

  1. xylan catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiGH11. Glycoside Hydrolase Family 11.

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanase 3 (EC:3.2.1.8)
Short name:
Xylanase 3
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase 3
Xylanase C
Gene namesi
Name:xynC
ORF Names:AKAW_07136
OrganismiAspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi)
Taxonomic identifieri1033177 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006812: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 27271 PublicationAdd
BLAST
Chaini28 – 211184Endo-1,4-beta-xylanase 3PRO_0000007991Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi119 ↔ 138

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

1
211
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi33 – 386
Helixi39 – 413
Beta strandi42 – 476
Helixi48 – 503
Beta strandi52 – 6312
Beta strandi65 – 739
Beta strandi79 – 868
Beta strandi90 – 10011
Turni101 – 1044
Beta strandi105 – 11511
Turni118 – 1214
Beta strandi122 – 1309
Beta strandi133 – 14715
Beta strandi150 – 16314
Beta strandi166 – 1705
Helixi172 – 1798
Helixi180 – 1823
Beta strandi187 – 21024

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1BK1X-ray2.00A28-211[»]
3RI8X-ray2.00A28-211[»]
3RI9X-ray2.00A28-211[»]
ProteinModelPortaliP33557.
SMRiP33557. Positions 29-210.

Miscellaneous databases

EvolutionaryTraceiP33557.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiEOG7VQJQX.

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR001137. Glyco_hydro_11.
IPR013319. Glyco_hydro_11/12.
IPR018208. Glyco_hydro_11_AS.
[Graphical view]
PfamiPF00457. Glyco_hydro_11. 1 hit.
[Graphical view]
PRINTSiPR00911. GLHYDRLASE11.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33557-1 [UniParc]FASTAAdd to Basket

« Hide

MKVTAAFAGL LVTAFAAPVP EPVLVSRSAG INYVQNYNGN LGDFTYDESA    50
GTFSMYWEDG VSSDFVVGLG WTTGSSNAIT YSAEYSASGS SSYLAVYGWV 100
NYPQAEYYIV EDYGDYNPCS SATSLGTVYS DGSTYQVCTD TRTNEPSITG 150
TSTFTQYFSV RESTRTSGTV TVANHFNFWA QHGFGNSDFN YQVMAVEAWS 200
GAGSASVTIS S 211
Length:211
Mass (Da):22,627
Last modified:March 21, 2012 - v2
Checksum:i86EFBEE12A869022
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti7 – 71F → S in AAC60542. 1 Publication
Sequence conflicti7 – 71F → S in BAA03576. 1 Publication
Sequence conflicti12 – 132VT → GH in AAC60542. 1 Publication
Sequence conflicti12 – 132VT → GH in BAA03576. 1 Publication
Sequence conflicti21 – 211E → Q in AAC60542. 1 Publication
Sequence conflicti21 – 211E → Q in BAA03576. 1 Publication
Sequence conflicti42 – 421G → A in AAC60542. 1 Publication
Sequence conflicti42 – 421G → A in BAA03576. 1 Publication
Sequence conflicti80 – 801T → S in AAC60542. 1 Publication
Sequence conflicti80 – 801T → S in BAA03576. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S45138 Genomic DNA. Translation: AAC60542.1.
D14848 Genomic DNA. Translation: BAA03576.1.
DF126466 Genomic DNA. Translation: GAA89022.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S45138 Genomic DNA. Translation: AAC60542.1 .
D14848 Genomic DNA. Translation: BAA03576.1 .
DF126466 Genomic DNA. Translation: GAA89022.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1BK1 X-ray 2.00 A 28-211 [» ]
3RI8 X-ray 2.00 A 28-211 [» ]
3RI9 X-ray 2.00 A 28-211 [» ]
ProteinModelPortali P33557.
SMRi P33557. Positions 29-210.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH11. Glycoside Hydrolase Family 11.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

OrthoDBi EOG7VQJQX.

Enzyme and pathway databases

UniPathwayi UPA00114 .

Miscellaneous databases

EvolutionaryTracei P33557.

Family and domain databases

Gene3Di 2.60.120.180. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR001137. Glyco_hydro_11.
IPR013319. Glyco_hydro_11/12.
IPR018208. Glyco_hydro_11_AS.
[Graphical view ]
Pfami PF00457. Glyco_hydro_11. 1 hit.
[Graphical view ]
PRINTSi PR00911. GLHYDRLASE11.
SUPFAMi SSF49899. SSF49899. 1 hit.
PROSITEi PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequencing of the xynC gene encoding acid xylanase of Aspergillus kawachii."
    Ito K., Iwashita K., Iwano K.
    Biosci. Biotechnol. Biochem. 56:1338-1340(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 28-34.
    Strain: NBRC 4308.
  2. "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used for brewing the Japanese distilled spirit shochu."
    Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H., Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.
    Eukaryot. Cell 10:1586-1587(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBRC 4308.
  3. "Crystallographic and mutational analyses of an extremely acidophilic and acid-stable xylanase: biased distribution of acidic residues and importance of Asp-37 for catalysis at low pH."
    Fushinobu S., Ito K., Konno M., Wakagi T., Matsuzawa H.
    Protein Eng. 11:1121-1128(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 29-210.
    Strain: NBRC 4308.

Entry informationi

Entry nameiXYN3_ASPKW
AccessioniPrimary (citable) accession number: P33557
Secondary accession number(s): G7XQI2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: March 21, 2012
Last modified: September 3, 2014
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi