ID   VNS2_BTV17              Reviewed;         354 AA.
AC   P33473;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   08-NOV-2023, entry version 45.
DE   RecName: Full=Non-structural protein NS2;
GN   Name=Segment-8;
OS   Bluetongue virus 17 (isolate USA) (BTV 17).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Sedoreoviridae; Orbivirus; Bluetongue virus.
OX   NCBI_TaxID=33718;
OH   NCBI_TaxID=9891; Antilocapra americana (Pronghorn).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=46212; Culicoides variipennis (Biting midge).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=2160765; DOI=10.1016/0168-1702(90)90032-7;
RA   Grubman M.J., Zellner M., Samal S.;
RT   "Nucleotide and deduced amino acid sequence of the nonstructural
RT   phosphoprotein, NS2, of bluetongue virus serotype 17: comparison to two
RT   isolates of serotype 10.";
RL   Virus Res. 15:243-250(1990).
CC   -!- FUNCTION: Single-stranded RNA-binding protein.
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DR   PIR; A60015; A60015.
DR   SMR; P33473; -.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR007602; BTV_NS2.
DR   InterPro; IPR037194; NS2_N.
DR   Pfam; PF04514; BTV_NS2; 1.
DR   SUPFAM; SSF110132; BTV NS2-like ssRNA-binding domain; 1.
PE   4: Predicted;
KW   RNA-binding.
FT   CHAIN           1..354
FT                   /note="Non-structural protein NS2"
FT                   /id="PRO_0000222677"
FT   REGION          163..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          229..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..196
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   354 AA;  40584 MW;  08E57C7EF46F43E6 CRC64;
     MEQKQRRFTK NIFVLDITAK TLCGAIAKLS SQPYCQIKIG RVVAFKPVKN PEPKGYVLNV
     PGPGAYRIQD GQDIISLMLT PHGVEATTER WEEWKFEGVS VTPMATRVQY NGVMVDAEIK
     YCKGMGIVQP YMRNDFDRNE MPDLPGVMRS NYDIRELRQK IKNERESAPR LQVQSVASRE
     ESRWMDDDEA KVDNEAKEII PGTSGLEKLR EARSNVFKEV ETVINWNLDE RDEEDRDERG
     DEEQVKTLSD DDDQGEDASD DEHPKTHITK EYIEKVAKQI KLKDERFMSL SSAMPQASGG
     FDRMIVTKKL KWQNVPLYCF DESLKRYELQ CVGACERVAF VSKDMSLIIL PVGV
//