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Protein

Non-structural protein NS2

Gene

S8

Organism
Bluetongue virus 17 (isolate USA) (BTV 17)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Single-stranded RNA-binding protein.

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein NS2
Gene namesi
Name:S8
OrganismiBluetongue virus 17 (isolate USA) (BTV 17)
Taxonomic identifieri33718 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeOrbivirus
Virus hostiAntilocapra americana (Pronghorn) [TaxID: 9891]
Bos taurus (Bovine) [TaxID: 9913]
Capra hircus (Goat) [TaxID: 9925]
Culicoides variipennis [TaxID: 46212]
Ovis aries (Sheep) [TaxID: 9940]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 354354Non-structural protein NS2PRO_0000222677Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP33473.
SMRiP33473. Positions 8-160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR007602. BTV_NS2.
[Graphical view]
PfamiPF04514. BTV_NS2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P33473-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQKQRRFTK NIFVLDITAK TLCGAIAKLS SQPYCQIKIG RVVAFKPVKN
60 70 80 90 100
PEPKGYVLNV PGPGAYRIQD GQDIISLMLT PHGVEATTER WEEWKFEGVS
110 120 130 140 150
VTPMATRVQY NGVMVDAEIK YCKGMGIVQP YMRNDFDRNE MPDLPGVMRS
160 170 180 190 200
NYDIRELRQK IKNERESAPR LQVQSVASRE ESRWMDDDEA KVDNEAKEII
210 220 230 240 250
PGTSGLEKLR EARSNVFKEV ETVINWNLDE RDEEDRDERG DEEQVKTLSD
260 270 280 290 300
DDDQGEDASD DEHPKTHITK EYIEKVAKQI KLKDERFMSL SSAMPQASGG
310 320 330 340 350
FDRMIVTKKL KWQNVPLYCF DESLKRYELQ CVGACERVAF VSKDMSLIIL

PVGV
Length:354
Mass (Da):40,584
Last modified:February 1, 1994 - v1
Checksum:i08E57C7EF46F43E6
GO

Sequence databases

PIRiA60015.

Cross-referencesi

Sequence databases

PIRiA60015.

3D structure databases

ProteinModelPortaliP33473.
SMRiP33473. Positions 8-160.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR007602. BTV_NS2.
[Graphical view]
PfamiPF04514. BTV_NS2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide and deduced amino acid sequence of the nonstructural phosphoprotein, NS2, of bluetongue virus serotype 17: comparison to two isolates of serotype 10."
    Grubman M.J., Zellner M., Samal S.
    Virus Res. 15:243-250(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiVNS2_BTV17
AccessioniPrimary (citable) accession number: P33473
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: April 3, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.