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Protein

Uncharacterized oxidoreductase YohF

Gene

yohF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei140SubstrateBy similarity1
Active sitei153Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi6 – 30NAD or NADPBy similarityAdd BLAST25

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:EG12019-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YohF (EC:1.-.-.-)
Gene namesi
Name:yohF
Synonyms:yohE
Ordered Locus Names:b2137, JW2125
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12019. yohF.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000548401 – 253Uncharacterized oxidoreductase YohFAdd BLAST253

Proteomic databases

PaxDbiP33368.
PRIDEiP33368.

Interactioni

Protein-protein interaction databases

BioGridi4260454. 12 interactors.
DIPiDIP-12806N.
IntActiP33368. 6 interactors.
STRINGi316385.ECDH10B_2293.

Structurei

3D structure databases

ProteinModelPortaliP33368.
SMRiP33368.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105H9W. Bacteria.
COG1028. LUCA.
InParanoidiP33368.
PhylomeDBiP33368.

Family and domain databases

InterProiView protein in InterPro
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00061. ADH_SHORT. 1 hit.

Sequencei

Sequence statusi: Complete.

P33368-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQVAIITAS DSGIGKECAL LLAQQGFDIG ITWHSDEEGA KDTAREVVSH
60 70 80 90 100
GVRAEIVQLD LGNLPEGALA LEKLIQRLGR IDVLVNNAGA MTKAPFLDMA
110 120 130 140 150
FDEWRKIFTV DVDGAFLCSQ IAARQMVKQG QGGRIINITS VHEHTPLPDA
160 170 180 190 200
SAYTAAKHAL GGLTKAMALE LVRHKILVNA VAPGAIATPM NGMDDSDVKP
210 220 230 240 250
DAEPSIPLRR FGATHEIASL VVWLCSEGAN YTTGQSLIVD GGFMLANPQF

NPE
Length:253
Mass (Da):26,951
Last modified:November 1, 1997 - v2
Checksum:iB030F9EAD7E8F42A
GO

Sequence cautioni

The sequence AAA60499 differs from that shown. Reason: Frameshift at position 185. Produces two separate ORFs.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA. Translation: AAA60500.1. Frameshift.
U00007 Genomic DNA. Translation: AAA60499.1. Frameshift.
U00096 Genomic DNA. Translation: AAC75198.1.
AP009048 Genomic DNA. Translation: BAE76614.1.
PIRiH64981.
RefSeqiNP_416641.1. NC_000913.3.
WP_000079538.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75198; AAC75198; b2137.
BAE76614; BAE76614; BAE76614.
GeneIDi949126.
KEGGiecj:JW2125.
eco:b2137.
PATRICifig|1411691.4.peg.105.

Similar proteinsi

Entry informationi

Entry nameiYOHF_ECOLI
AccessioniPrimary (citable) accession number: P33368
Secondary accession number(s): P33367, P76437, Q2MAU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: November 1, 1997
Last modified: August 30, 2017
This is version 124 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families