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P33368

- YOHF_ECOLI

UniProt

P33368 - YOHF_ECOLI

Protein

Uncharacterized oxidoreductase YohF

Gene

yohF

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 2 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei140 – 1401SubstrateBy similarity
    Active sitei153 – 1531Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi6 – 3025NAD or NADPBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. oxidoreductase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciEcoCyc:EG12019-MONOMER.
    ECOL316407:JW2125-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized oxidoreductase YohF (EC:1.-.-.-)
    Gene namesi
    Name:yohF
    Synonyms:yohE
    Ordered Locus Names:b2137, JW2125
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG12019. yohF.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 253253Uncharacterized oxidoreductase YohFPRO_0000054840Add
    BLAST

    Proteomic databases

    PaxDbiP33368.
    PRIDEiP33368.

    Expressioni

    Gene expression databases

    GenevestigatoriP33368.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-12806N.
    IntActiP33368. 6 interactions.
    STRINGi511145.b2137.

    Structurei

    3D structure databases

    ProteinModelPortaliP33368.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1028.
    KOiK00540.
    OMAiFIIDGGF.
    OrthoDBiEOG6N3CR8.
    PhylomeDBiP33368.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view]
    PfamiPF00106. adh_short. 1 hit.
    [Graphical view]
    PRINTSiPR00081. GDHRDH.
    PR00080. SDRFAMILY.
    PROSITEiPS00061. ADH_SHORT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P33368-1 [UniParc]FASTAAdd to Basket

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    MAQVAIITAS DSGIGKECAL LLAQQGFDIG ITWHSDEEGA KDTAREVVSH    50
    GVRAEIVQLD LGNLPEGALA LEKLIQRLGR IDVLVNNAGA MTKAPFLDMA 100
    FDEWRKIFTV DVDGAFLCSQ IAARQMVKQG QGGRIINITS VHEHTPLPDA 150
    SAYTAAKHAL GGLTKAMALE LVRHKILVNA VAPGAIATPM NGMDDSDVKP 200
    DAEPSIPLRR FGATHEIASL VVWLCSEGAN YTTGQSLIVD GGFMLANPQF 250
    NPE 253
    Length:253
    Mass (Da):26,951
    Last modified:November 1, 1997 - v2
    Checksum:iB030F9EAD7E8F42A
    GO

    Sequence cautioni

    The sequence AAA60499.1 differs from that shown. Reason: Frameshift at position 185. Produces two separate ORFs.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00007 Genomic DNA. Translation: AAA60500.1. Frameshift.
    U00007 Genomic DNA. Translation: AAA60499.1. Frameshift.
    U00096 Genomic DNA. Translation: AAC75198.1.
    AP009048 Genomic DNA. Translation: BAE76614.1.
    PIRiH64981.
    RefSeqiNP_416641.1. NC_000913.3.
    YP_490376.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC75198; AAC75198; b2137.
    BAE76614; BAE76614; BAE76614.
    GeneIDi12931460.
    949126.
    KEGGiecj:Y75_p2099.
    eco:b2137.
    PATRICi32119617. VBIEscCol129921_2219.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00007 Genomic DNA. Translation: AAA60500.1 . Frameshift.
    U00007 Genomic DNA. Translation: AAA60499.1 . Frameshift.
    U00096 Genomic DNA. Translation: AAC75198.1 .
    AP009048 Genomic DNA. Translation: BAE76614.1 .
    PIRi H64981.
    RefSeqi NP_416641.1. NC_000913.3.
    YP_490376.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P33368.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-12806N.
    IntActi P33368. 6 interactions.
    STRINGi 511145.b2137.

    Proteomic databases

    PaxDbi P33368.
    PRIDEi P33368.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC75198 ; AAC75198 ; b2137 .
    BAE76614 ; BAE76614 ; BAE76614 .
    GeneIDi 12931460.
    949126.
    KEGGi ecj:Y75_p2099.
    eco:b2137.
    PATRICi 32119617. VBIEscCol129921_2219.

    Organism-specific databases

    EchoBASEi EB1955.
    EcoGenei EG12019. yohF.

    Phylogenomic databases

    eggNOGi COG1028.
    KOi K00540.
    OMAi FIIDGGF.
    OrthoDBi EOG6N3CR8.
    PhylomeDBi P33368.

    Enzyme and pathway databases

    BioCyci EcoCyc:EG12019-MONOMER.
    ECOL316407:JW2125-MONOMER.

    Miscellaneous databases

    PROi P33368.

    Gene expression databases

    Genevestigatori P33368.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view ]
    Pfami PF00106. adh_short. 1 hit.
    [Graphical view ]
    PRINTSi PR00081. GDHRDH.
    PR00080. SDRFAMILY.
    PROSITEi PS00061. ADH_SHORT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Automated multiplex sequencing of the E.coli genome."
      Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M.
      Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / BHB2600.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiYOHF_ECOLI
    AccessioniPrimary (citable) accession number: P33368
    Secondary accession number(s): P33367, P76437, Q2MAU2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 102 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3