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P33368

- YOHF_ECOLI

UniProt

P33368 - YOHF_ECOLI

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Protein

Uncharacterized oxidoreductase YohF

Gene

yohF

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei140 – 1401SubstrateBy similarity
Active sitei153 – 1531Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 3025NAD or NADPBy similarityAdd
BLAST

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:EG12019-MONOMER.
ECOL316407:JW2125-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YohF (EC:1.-.-.-)
Gene namesi
Name:yohF
Synonyms:yohE
Ordered Locus Names:b2137, JW2125
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG12019. yohF.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 253253Uncharacterized oxidoreductase YohFPRO_0000054840Add
BLAST

Proteomic databases

PaxDbiP33368.
PRIDEiP33368.

Expressioni

Gene expression databases

GenevestigatoriP33368.

Interactioni

Protein-protein interaction databases

DIPiDIP-12806N.
IntActiP33368. 6 interactions.
STRINGi511145.b2137.

Structurei

3D structure databases

ProteinModelPortaliP33368.
SMRiP33368. Positions 2-242.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1028.
InParanoidiP33368.
KOiK00540.
OMAiFIIDGGF.
OrthoDBiEOG6N3CR8.
PhylomeDBiP33368.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P33368-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQVAIITAS DSGIGKECAL LLAQQGFDIG ITWHSDEEGA KDTAREVVSH
60 70 80 90 100
GVRAEIVQLD LGNLPEGALA LEKLIQRLGR IDVLVNNAGA MTKAPFLDMA
110 120 130 140 150
FDEWRKIFTV DVDGAFLCSQ IAARQMVKQG QGGRIINITS VHEHTPLPDA
160 170 180 190 200
SAYTAAKHAL GGLTKAMALE LVRHKILVNA VAPGAIATPM NGMDDSDVKP
210 220 230 240 250
DAEPSIPLRR FGATHEIASL VVWLCSEGAN YTTGQSLIVD GGFMLANPQF

NPE
Length:253
Mass (Da):26,951
Last modified:November 1, 1997 - v2
Checksum:iB030F9EAD7E8F42A
GO

Sequence cautioni

The sequence AAA60499.1 differs from that shown. Reason: Frameshift at position 185. Produces two separate ORFs.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA. Translation: AAA60500.1. Frameshift.
U00007 Genomic DNA. Translation: AAA60499.1. Frameshift.
U00096 Genomic DNA. Translation: AAC75198.1.
AP009048 Genomic DNA. Translation: BAE76614.1.
PIRiH64981.
RefSeqiNP_416641.1. NC_000913.3.
YP_490376.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC75198; AAC75198; b2137.
BAE76614; BAE76614; BAE76614.
GeneIDi12931460.
949126.
KEGGiecj:Y75_p2099.
eco:b2137.
PATRICi32119617. VBIEscCol129921_2219.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA. Translation: AAA60500.1 . Frameshift.
U00007 Genomic DNA. Translation: AAA60499.1 . Frameshift.
U00096 Genomic DNA. Translation: AAC75198.1 .
AP009048 Genomic DNA. Translation: BAE76614.1 .
PIRi H64981.
RefSeqi NP_416641.1. NC_000913.3.
YP_490376.1. NC_007779.1.

3D structure databases

ProteinModelPortali P33368.
SMRi P33368. Positions 2-242.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-12806N.
IntActi P33368. 6 interactions.
STRINGi 511145.b2137.

Proteomic databases

PaxDbi P33368.
PRIDEi P33368.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC75198 ; AAC75198 ; b2137 .
BAE76614 ; BAE76614 ; BAE76614 .
GeneIDi 12931460.
949126.
KEGGi ecj:Y75_p2099.
eco:b2137.
PATRICi 32119617. VBIEscCol129921_2219.

Organism-specific databases

EchoBASEi EB1955.
EcoGenei EG12019. yohF.

Phylogenomic databases

eggNOGi COG1028.
InParanoidi P33368.
KOi K00540.
OMAi FIIDGGF.
OrthoDBi EOG6N3CR8.
PhylomeDBi P33368.

Enzyme and pathway databases

BioCyci EcoCyc:EG12019-MONOMER.
ECOL316407:JW2125-MONOMER.

Miscellaneous databases

PROi P33368.

Gene expression databases

Genevestigatori P33368.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view ]
Pfami PF00106. adh_short. 1 hit.
[Graphical view ]
PRINTSi PR00081. GDHRDH.
PR00080. SDRFAMILY.
PROSITEi PS00061. ADH_SHORT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Automated multiplex sequencing of the E.coli genome."
    Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / BHB2600.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYOHF_ECOLI
AccessioniPrimary (citable) accession number: P33368
Secondary accession number(s): P33367, P76437, Q2MAU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3