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Protein

Periplasmic beta-glucosidase

Gene

bglX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei287By similarity1

GO - Molecular functioni

  • beta-glucosidase activity Source: EcoliWiki
  • glucosidase activity Source: EcoliWiki
  • scopolin beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Enzyme and pathway databases

BioCyciEcoCyc:EG12013-MONOMER
MetaCyc:EG12013-MONOMER

Protein family/group databases

CAZyiGH3 Glycoside Hydrolase Family 3

Names & Taxonomyi

Protein namesi
Recommended name:
Periplasmic beta-glucosidase (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene namesi
Name:bglX
Synonyms:yohA
Ordered Locus Names:b2132, JW2120
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12013 bglX

Subcellular locationi

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc
  • periplasmic space Source: EcoliWiki
  • plasma membrane Source: GO_Central

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000001178121 – 765Periplasmic beta-glucosidaseAdd BLAST745

Proteomic databases

EPDiP33363
PaxDbiP33363
PRIDEiP33363

Interactioni

Protein-protein interaction databases

BioGridi4260451, 32 interactors
DIPiDIP-9218N
IntActiP33363, 16 interactors
STRINGi316385.ECDH10B_2288

Structurei

3D structure databases

ProteinModelPortaliP33363
SMRiP33363
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107QK4 Bacteria
COG1472 LUCA
HOGENOMiHOG000031217
InParanoidiP33363
KOiK05349
OMAiIGPMAHG
PhylomeDBiP33363

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.20.20.300, 1 hit
3.40.50.1700, 1 hit
InterProiView protein in InterPro
IPR026891 Fn3-like
IPR019800 Glyco_hydro_3_AS
IPR002772 Glyco_hydro_3_C
IPR036881 Glyco_hydro_3_C_sf
IPR001764 Glyco_hydro_3_N
IPR036962 Glyco_hydro_3_N_sf
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF14310 Fn3-like, 1 hit
PF00933 Glyco_hydro_3, 1 hit
PF01915 Glyco_hydro_3_C, 1 hit
PRINTSiPR00133 GLHYDRLASE3
SMARTiView protein in SMART
SM01217 Fn3_like, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF52279 SSF52279, 2 hits
PROSITEiView protein in PROSITE
PS00775 GLYCOSYL_HYDROL_F3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33363-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWLCSVGIA VSLALQPALA DDLFGNHPLT PEARDAFVTE LLKKMTVDEK
60 70 80 90 100
IGQLRLISVG PDNPKEAIRE MIKDGQVGAI FNTVTRQDIR AMQDQVMELS
110 120 130 140 150
RLKIPLFFAY DVLHGQRTVF PISLGLASSF NLDAVKTVGR VSAYEAADDG
160 170 180 190 200
LNMTWAPMVD VSRDPRWGRA SEGFGEDTYL TSTMGKTMVE AMQGKSPADR
210 220 230 240 250
YSVMTSVKHF AAYGAVEGGK EYNTVDMSPQ RLFNDYMPPY KAGLDAGSGA
260 270 280 290 300
VMVALNSLNG TPATSDSWLL KDVLRDQWGF KGITVSDHGA IKELIKHGTA
310 320 330 340 350
ADPEDAVRVA LKSGINMSMS DEYYSKYLPG LIKSGKVTMA ELDDAARHVL
360 370 380 390 400
NVKYDMGLFN DPYSHLGPKE SDPVDTNAES RLHRKEAREV ARESLVLLKN
410 420 430 440 450
RLETLPLKKS ATIAVVGPLA DSKRDVMGSW SAAGVADQSV TVLTGIKNAV
460 470 480 490 500
GENGKVLYAK GANVTSDKGI IDFLNQYEEA VKVDPRSPQE MIDEAVQTAK
510 520 530 540 550
QSDVVVAVVG EAQGMAHEAS SRTDITIPQS QRDLIAALKA TGKPLVLVLM
560 570 580 590 600
NGRPLALVKE DQQADAILET WFAGTEGGNA IADVLFGDYN PSGKLPMSFP
610 620 630 640 650
RSVGQIPVYY SHLNTGRPYN ADKPNKYTSR YFDEANGALY PFGYGLSYTT
660 670 680 690 700
FTVSDVKLSA PTMKRDGKVT ASVQVTNTGK REGATVVQMY LQDVTASMSR
710 720 730 740 750
PVKQLKGFEK ITLKPGETQT VSFPIDIEAL KFWNQQMKYD AEPGKFNVFI
760
GTDSARVKKG EFELL
Length:765
Mass (Da):83,460
Last modified:February 1, 1995 - v2
Checksum:i0E89B0AB42B8F8F3
GO

Sequence cautioni

The sequence AAA60495 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15049 Genomic DNA Translation: AAB38487.1
U00007 Genomic DNA Translation: AAA60495.1 Different initiation.
U00096 Genomic DNA Translation: AAC75193.1
AP009048 Genomic DNA Translation: BAE76609.1
PIRiC64981
RefSeqiNP_416636.1, NC_000913.3
WP_000871504.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75193; AAC75193; b2132
BAE76609; BAE76609; BAE76609
GeneIDi946682
KEGGiecj:JW2120
eco:b2132
PATRICifig|511145.12.peg.2212

Similar proteinsi

Entry informationi

Entry nameiBGLX_ECOLI
AccessioniPrimary (citable) accession number: P33363
Secondary accession number(s): Q2MAU7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 135 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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