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P33345

- MOLR_ECOLI

UniProt

P33345 - MOLR_ECOLI

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Protein

Putative molybdate metabolism regulator

Gene

yehH

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini

Functioni

Was originally thought to be involved in the regulation of molybdate metabolism (PubMed:2156810), has also been implicated in selenate reduction (PubMed:12480890).2 Publications

Enzyme and pathway databases

BioCyciEcoCyc:EG11992-MONOMER.
EcoCyc:G8208-MONOMER.
EcoCyc:G8209-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative molybdate metabolism regulator
Gene namesi
Name:yehH
Synonyms:molR
Ordered Locus Names:b4499
ORF Names:b2115/b2116/b2117
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000625: Chromosome

Organism-specific databases

EcoGeneiEG11992. yehH.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12641264Putative molybdate metabolism regulatorPRO_0000096531Add
BLAST

Proteomic databases

PRIDEiP33345.

Expressioni

Gene expression databases

GenevestigatoriP33345.

Interactioni

Protein-protein interaction databases

IntActiP33345. 8 interactions.

Structurei

3D structure databases

ProteinModelPortaliP33345.
SMRiP33345. Positions 2-70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To E.coli YehI.Curated

Phylogenomic databases

HOGENOMiHOG000122164.

Family and domain databases

Gene3Di2.20.140.10. 1 hit.
InterProiIPR025406. DUF4132.
IPR008893. WGR_domain.
[Graphical view]
PfamiPF13569. DUF4132. 1 hit.
PF05406. WGR. 1 hit.
[Graphical view]
SMARTiSM00773. WGR. 1 hit.
[Graphical view]
SUPFAMiSSF142921. SSF142921. 1 hit.

Sequencei

Sequence statusi: Complete.

P33345-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRHFIYQDEK SHKFRAVEQQ GNELHISWGK VGTKGQSQIK SFSDAAAAAK
60 70 80 90 100
AELKLIAEKV KKGYVEQAKD NSLQPSQTVT GSLKVADLST IIQEQPSFVA
110 120 130 140 150
ETRAPDKNTD AVLPWLAKDI AVVFPPEVVH TTLSHRRFPG VPVQQADKLP
160 170 180 190 200
QLRRLACSVS QRDNKTATFD FSACSLEWQN TVAQAISQID GLKTTQLPSP
210 220 230 240 250
VMAVLTALEM KCTRYKVRED VMDQIVQEGG LEYATDVIIH LQQIDIEWDY
260 270 280 290 300
ANNVIIILPS GIAPSYLEQY SRFEXRLRKH LSLTEESLWQ KCAQKLIAAI
310 320 330 340 350
PHIPEWRQPL IALLLPEKPE IAHEIAQRLL GQKKLPSLEW LKIVATDEHI
360 370 380 390 400
LASLEKYHEP YAIFDDYYCG AIWSATVLQE QGVAALPRFA PYAASDYCAD
410 420 430 440 450
VLRHINHPFA LTLLIRVAGQ TKRCHDRMTK AIAAFPHAAM AALTELLGQK
460 470 480 490 500
EENSWRIMLM TMLISQPALA EQVIPWLSTP AVAVLKSCQQ QLTQPSNHAS
510 520 530 540 550
ADLLPAVVVS PPWLSKKKKS PIPVLDLAPL GIEPICYLTE EISNQLLAKY
560 570 580 590 600
IWYSKHITVS HEESTTNLLA RMGFQRRIAG TYIKAPEAVV EAWLNEDYST
610 620 630 640 650
LLSEFKVFHS PTGHYWQLGI LTTLPLEKAV KAWNALTLSP HTDTEYSMLH
660 670 680 690 700
FGLKGLPGLV NSLARYPQEA LPITNYFAAS ELAPAVARAF NKLKTLRENA
710 720 730 740 750
RSWLLKYPEH ALTGLLPAAP GKAGEAQDNA RAALRMLTEN GHQPLLQEIA
760 770 780 790 800
RRYNQPEVTD AVNALLALDP LDNHPTKIPT LPAFYQPSLW TRPVLKANAQ
810 820 830 840 850
SLPDSALLHL GEMLRFPQEE ALYPGLLQVK DVCSADSLAG FAWDLFTAWQ
860 870 880 890 900
TAGAPSKESW AFTALGVLGN DDTARKLTPL IRAWPGESQH KRATVGLDIL
910 920 930 940 950
AAIGSDIALM QLNGIAQKLK FKALQERAKE KIADIAESRE LTVAELEDRL
960 970 980 990 1000
APDLGLDDNG SLLLDFGPRQ FTVSFDETLK PFVRDVSGSR LKDLPKPNKS
1010 1020 1030 1040 1050
DDETRANDAV NRYKLLKKDA RTIAAQQVAR LESAMCLRRR WSLENFQLFL
1060 1070 1080 1090 1100
VEHPLVRHLT RRLIWGVYSA ENQLLACFRV AEDNSSSTAD DDLFTLPEGD
1110 1120 1130 1140 1150
ISIGTPHVLE ISPTDAAAFG QLFADYELLP PFRQLDRNSY ALTEAERNAS
1160 1170 1180 1190 1200
ELTRWAGRKC PSGRVMGLAN KGWIKGEPQD GGWIGWMIKP LGRWSLIMEI
1210 1220 1230 1240 1250
DEGFAVGMSP AELSAEQLLS KLWLWEGKAE RYGWGSNSTQ EAQFSVIDAI
1260
TASELINDIE ALFE
Length:1,264
Mass (Da):140,939
Last modified:February 1, 1994 - v1
Checksum:iFCB85A5933CCEFF4
GO

Sequence cautioni

The sequence AAA60477.1 differs from that shown. Reason: Frameshift at positions 275 and 950.
The sequence U00096 differs from that shown. Reason: Frameshift at positions 275 and 950.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00007 Genomic DNA. Translation: AAA60477.1. Frameshift.
U00096 Genomic DNA. No translation available.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00007 Genomic DNA. Translation: AAA60477.1 . Frameshift.
U00096 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali P33345.
SMRi P33345. Positions 2-70.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P33345. 8 interactions.

Proteomic databases

PRIDEi P33345.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

EchoBASEi EB1935.
EcoGenei EG11992. yehH.

Phylogenomic databases

HOGENOMi HOG000122164.

Enzyme and pathway databases

BioCyci EcoCyc:EG11992-MONOMER.
EcoCyc:G8208-MONOMER.
EcoCyc:G8209-MONOMER.

Gene expression databases

Genevestigatori P33345.

Family and domain databases

Gene3Di 2.20.140.10. 1 hit.
InterProi IPR025406. DUF4132.
IPR008893. WGR_domain.
[Graphical view ]
Pfami PF13569. DUF4132. 1 hit.
PF05406. WGR. 1 hit.
[Graphical view ]
SMARTi SM00773. WGR. 1 hit.
[Graphical view ]
SUPFAMi SSF142921. SSF142921. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Automated multiplex sequencing of the E.coli genome."
    Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / BHB2600.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Identification of a new gene, molR, essential for utilization of molybdate by Escherichia coli."
    Lee J.H., Wendt J.C., Shanmugam K.T.
    J. Bacteriol. 172:2079-2087(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.
    Strain: K12 / BW545.
  4. Healy F., Grunden A., Ray R.M., Shanmugam K.T.
    Unpublished observations (FEB-1994)
    Cited for: CHARACTERIZATION.
  5. "Involvement of a putative molybdenum enzyme in the reduction of selenate by Escherichia coli."
    Bebien M., Kirsch J., Mejean V., Vermeglio A.
    Microbiology 148:3865-3872(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: POTENTIAL INVOLVEMENT IN SELENATE REDUCTION.
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.

Entry informationi

Entry nameiMOLR_ECOLI
AccessioniPrimary (citable) accession number: P33345
Secondary accession number(s): P76427, P76428, P76429
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

External Data

Dasty 3