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Protein

Probable fimbrial chaperone YehC

Gene

yehC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the yehABCD fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Fimbrium biogenesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11989-MONOMER.
ECOL316407:JW2097-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable fimbrial chaperone YehC
Gene namesi
Name:yehC
Ordered Locus Names:b2110, JW2097
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11989. yehC.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

Pathology & Biotechi

Disruption phenotypei

Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Sequence analysisAdd
BLAST
Chaini32 – 239208Probable fimbrial chaperone YehCPRO_0000009293Add
BLAST

Proteomic databases

PaxDbiP33342.
PRIDEiP33342.

Expressioni

Inductioni

Expression is negatively regulated by H-NS and subjected to cAMP receptor protein (CRP)-mediated catabolite repression.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260436. 27 interactions.
IntActiP33342. 3 interactions.
STRINGi511145.b2110.

Structurei

3D structure databases

ProteinModelPortaliP33342.
SMRiP33342. Positions 39-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the periplasmic pilus chaperone family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiENOG4108MQF. Bacteria.
COG3121. LUCA.
HOGENOMiHOG000260152.
OMAiTIMIAPQ.
PhylomeDBiP33342.

Family and domain databases

Gene3Di2.60.40.1070. 1 hit.
2.60.40.360. 1 hit.
InterProiIPR008962. PapD-like.
IPR001829. Pili_assmbl_chaperone_bac.
IPR016148. Pili_assmbl_chaperone_C.
IPR018046. Pili_assmbl_chaperone_CS.
IPR016147. Pili_assmbl_chaperone_N.
[Graphical view]
PfamiPF02753. PapD_C. 1 hit.
PF00345. PapD_N. 1 hit.
[Graphical view]
PRINTSiPR00969. CHAPERONPILI.
SUPFAMiSSF49354. SSF49354. 1 hit.
SSF49584. SSF49584. 1 hit.
PROSITEiPS00635. PILI_CHAPERONE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33342-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAIPWRPFN LRGIKMKGLL SLLIFSMVLP AHAGIVIYGT RIIYPAENKE
60 70 80 90 100
VMVQLMNQGN RSSLLQAWID DGDTSLPPEK IQVPFMLTPP VAKIGANSGQ
110 120 130 140 150
QVKIKIMPNK LPTNKESIFY LNVLDIPPNS PEQEGKNALK FAMQNRIKLF
160 170 180 190 200
YRPAGIAPVN KATFKKLLVN RSGNGLVIKN DSANWVTISD VKANNVKVNY
210 220 230
ETIMIAPLES QSVNVKSNNA NNWHLTIIDD HGNYISDKI
Length:239
Mass (Da):26,589
Last modified:February 1, 1994 - v1
Checksum:i78B84A20BFAB39A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA. Translation: AAA60474.1.
U00096 Genomic DNA. Translation: AAC75171.1.
AP009048 Genomic DNA. Translation: BAE76588.1.
PIRiE64978.
RefSeqiNP_416613.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC75171; AAC75171; b2110.
BAE76588; BAE76588; BAE76588.
GeneIDi946621.
KEGGiecj:JW2097.
eco:b2110.
PATRICi32119553. VBIEscCol129921_2187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00007 Genomic DNA. Translation: AAA60474.1.
U00096 Genomic DNA. Translation: AAC75171.1.
AP009048 Genomic DNA. Translation: BAE76588.1.
PIRiE64978.
RefSeqiNP_416613.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP33342.
SMRiP33342. Positions 39-232.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260436. 27 interactions.
IntActiP33342. 3 interactions.
STRINGi511145.b2110.

Proteomic databases

PaxDbiP33342.
PRIDEiP33342.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75171; AAC75171; b2110.
BAE76588; BAE76588; BAE76588.
GeneIDi946621.
KEGGiecj:JW2097.
eco:b2110.
PATRICi32119553. VBIEscCol129921_2187.

Organism-specific databases

EchoBASEiEB1932.
EcoGeneiEG11989. yehC.

Phylogenomic databases

eggNOGiENOG4108MQF. Bacteria.
COG3121. LUCA.
HOGENOMiHOG000260152.
OMAiTIMIAPQ.
PhylomeDBiP33342.

Enzyme and pathway databases

BioCyciEcoCyc:EG11989-MONOMER.
ECOL316407:JW2097-MONOMER.

Miscellaneous databases

PROiP33342.

Family and domain databases

Gene3Di2.60.40.1070. 1 hit.
2.60.40.360. 1 hit.
InterProiIPR008962. PapD-like.
IPR001829. Pili_assmbl_chaperone_bac.
IPR016148. Pili_assmbl_chaperone_C.
IPR018046. Pili_assmbl_chaperone_CS.
IPR016147. Pili_assmbl_chaperone_N.
[Graphical view]
PfamiPF02753. PapD_C. 1 hit.
PF00345. PapD_N. 1 hit.
[Graphical view]
PRINTSiPR00969. CHAPERONPILI.
SUPFAMiSSF49354. SSF49354. 1 hit.
SSF49584. SSF49584. 1 hit.
PROSITEiPS00635. PILI_CHAPERONE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYEHC_ECOLI
AccessioniPrimary (citable) accession number: P33342
Secondary accession number(s): Q2MAW8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: September 7, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.