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Protein

Flagellar hook-associated protein 1

Gene

flgK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • bacterial-type flagellum assembly Source: EcoCyc
  • bacterial-type flagellum-dependent cell motility Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11967-MONOMER.
ECOL316407:JW1069-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar hook-associated protein 1
Short name:
HAP1
Gene namesi
Name:flgK
Synonyms:flaS, flaW
Ordered Locus Names:b1082, JW1069
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11967. flgK.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 547546Flagellar hook-associated protein 1PRO_0000180862Add
BLAST

Proteomic databases

EPDiP33235.
PaxDbiP33235.
PRIDEiP33235.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
flgNP435333EBI-551382,EBI-1121833

Protein-protein interaction databases

BioGridi4261021. 7 interactions.
DIPiDIP-9639N.
IntActiP33235. 7 interactions.
MINTiMINT-1322777.
STRINGi511145.b1082.

Structurei

3D structure databases

ProteinModelPortaliP33235.
SMRiP33235. Positions 68-506.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105E1Q. Bacteria.
COG1256. LUCA.
HOGENOMiHOG000265598.
InParanoidiP33235.
KOiK02396.
OMAiFQQYYMA.
OrthoDBiEOG6NWBMH.
PhylomeDBiP33235.

Family and domain databases

InterProiIPR001444. Flag_bb_rod_N.
IPR010930. Flg_bb/hook_C_dom.
IPR002371. FlgK.
[Graphical view]
PfamiPF00460. Flg_bb_rod. 1 hit.
PF06429. Flg_bbr_C. 1 hit.
[Graphical view]
PRINTSiPR01005. FLGHOOKAP1.
TIGRFAMsiTIGR02492. flgK_ends. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33235-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLINNAMS GLNAAQAALN TASNNISSYN VAGYTRQTTI MAQANSTLGA
60 70 80 90 100
GGWVGNGVYV SGVQREYDAF ITNQLRAAQT QSSGLTARYE QMSKIDNMLS
110 120 130 140 150
TSTSSLATQM QDFFTSLQTL VSNAEDPAAR QALIGKSEGL VNQFKTTDQY
160 170 180 190 200
LRDQDKQVNI AIGASVDQIN NYAKQIASLN DQISRLTGVG AGASPNNLLD
210 220 230 240 250
QRDQLVSELN QIVGVEVSVQ DGGTYNITMA NGYSLVQGST ARQLAAVPSS
260 270 280 290 300
ADPSRTTVAY VDGTAGNIEI PEKLLNTGSL GGILTFRSQD LDQTRNTLGQ
310 320 330 340 350
LALAFAEAFN TQHKAGFDAN GDAGEDFFAI GKPAVLQNTK NKGDVAIGAT
360 370 380 390 400
VTDASAVLAT DYKISFDNNQ WQVTRLASNT TFTVTPDANG KVAFDGLELT
410 420 430 440 450
FTGTPAVNDS FTLKPVSDAI VNMDVLITDE AKIAMASEED AGDSDNRNGQ
460 470 480 490 500
ALLDLQSNSK TVGGAKSFND AYASLVSDIG NKTATLKTSS ATQGNVVTQL
510 520 530 540
SNQQQSISGV NLDEEYGNLQ RFQQYYLANA QVLQTANAIF DALINIR
Length:547
Mass (Da):57,930
Last modified:January 23, 2007 - v3
Checksum:i2A7D15933C0F999C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74166.1.
AP009048 Genomic DNA. Translation: BAA35891.1.
U02514 Unassigned DNA. Translation: AAA18321.1.
PIRiG64851.
RefSeqiNP_415600.1. NC_000913.3.
WP_000096479.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74166; AAC74166; b1082.
BAA35891; BAA35891; BAA35891.
GeneIDi945648.
KEGGiecj:JW1069.
eco:b1082.
PATRICi32117405. VBIEscCol129921_1125.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74166.1.
AP009048 Genomic DNA. Translation: BAA35891.1.
U02514 Unassigned DNA. Translation: AAA18321.1.
PIRiG64851.
RefSeqiNP_415600.1. NC_000913.3.
WP_000096479.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP33235.
SMRiP33235. Positions 68-506.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261021. 7 interactions.
DIPiDIP-9639N.
IntActiP33235. 7 interactions.
MINTiMINT-1322777.
STRINGi511145.b1082.

Proteomic databases

EPDiP33235.
PaxDbiP33235.
PRIDEiP33235.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74166; AAC74166; b1082.
BAA35891; BAA35891; BAA35891.
GeneIDi945648.
KEGGiecj:JW1069.
eco:b1082.
PATRICi32117405. VBIEscCol129921_1125.

Organism-specific databases

EchoBASEiEB1910.
EcoGeneiEG11967. flgK.

Phylogenomic databases

eggNOGiENOG4105E1Q. Bacteria.
COG1256. LUCA.
HOGENOMiHOG000265598.
InParanoidiP33235.
KOiK02396.
OMAiFQQYYMA.
OrthoDBiEOG6NWBMH.
PhylomeDBiP33235.

Enzyme and pathway databases

BioCyciEcoCyc:EG11967-MONOMER.
ECOL316407:JW1069-MONOMER.

Miscellaneous databases

PROiP33235.

Family and domain databases

InterProiIPR001444. Flag_bb_rod_N.
IPR010930. Flg_bb/hook_C_dom.
IPR002371. FlgK.
[Graphical view]
PfamiPF00460. Flg_bb_rod. 1 hit.
PF06429. Flg_bbr_C. 1 hit.
[Graphical view]
PRINTSiPR01005. FLGHOOKAP1.
TIGRFAMsiTIGR02492. flgK_ends. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "A mutant hook-associated protein (HAP3) facilitates torsionally induced transformations of the flagellar filament of Escherichia coli."
    Fahrner K.A., Block S.M., Krishnaswamy S., Parkinson J.S., Berg H.C.
    J. Mol. Biol. 238:173-186(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 536-547.
    Strain: K12 / CS520.

Entry informationi

Entry nameiFLGK_ECOLI
AccessioniPrimary (citable) accession number: P33235
Secondary accession number(s): P77680
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 23, 2007
Last modified: April 13, 2016
This is version 124 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.