Reviewed, UniProtKB/Swiss-Prot P33234 (ADIY_ECOLI)

Names and origin

Protein names

Recommended name:
    HTH-type transcriptional regulator adiY

Gene names

Name:	adiY
Ordered Locus Names:	b4116, JW4077

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	253 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 1 HTH araC/xylS-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro transcription Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
groL	P0A6F5	1	EBI-1119007,EBI-543750

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 253	253	HTH-type transcriptional regulator adiY		PRO_0000194495
Regions
	DNA binding	165 – 184	20	H-T-H motif By similarity

Sequences

	Sequence		Length	Mass (Da)
	P33234-1 [UniParc]. Last modified February 1, 1994. Version 1. Checksum: 6A7DE2B06E60389E	FASTA	253	29,007
	10 20 30 40 50 60 MRICSDQPCI VLLTEKDVWI RVNGKEPISL KANHMALLNC ENNIIDVSSL NNTLVAHISH 70 80 90 100 110 120 DIIKDYLRFL NKDLSQIPVW QRSATPILTL PCLTPDVFRV AAQHSMMPAE TESEKERTRA 130 140 150 160 170 180 LLFTVLSRFL DSKKFVSLMM YMLRNCVSDS VYQIIESDIH KDWNLSMVAS CLCLSPSLLK 190 200 210 220 230 240 KKLKSENTSY SQIITTCRMR YAVNELMMDG KNISQVSQSC GYNSTSYFIS VFKDFYGMTP 250 LHYVSQHRER TVA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stim K.P., Bennett G.N. Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed: 7610040] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U02384 Unassigned DNA. Translation: AAB18143.1. U14003 Genomic DNA. Translation: AAA97016.1. U00096 Genomic DNA. Translation: AAC77077.1. AP009048 Genomic DNA. Translation: BAE78118.1.
PIR	S56345.
RefSeq	AP_004617.1. NP_418540.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P33234. 2 interactions.
STRING	P33234.
Protein family/group databases
AraC-XylS	Search...
Genome annotation databases
GeneID	948627.
GenomeReviews	Gene locus JW4077 in contig AP009048_GR. Gene locus b4116 in contig U00096_GR.
KEGG	ecj:JW4077. eco:b4116.
Organism-specific databases
EchoBASE	EB1909.
EcoGene	EG11966. adiY.
CMR	Search...
Phylogenomic databases
HOGENOM	P33234.
OMA	ACENNII
Enzyme and pathway databases
BioCyc	EcoCyc:EG11966-MON. ECOL168927:B4116-MON.
Gene expression databases
Genevestigator	P33234.
Family and domain databases
InterPro	IPR020449. Helix-turn-helix_AraC. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. IPR000005. HTH_AraC-typ. IPR018062. HTH_AraC-typ_sub_2. IPR018060. HTH_AraC_domain. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00165. HTH_AraC. 2 hits. [Graphical view]
PRINTS	PR00032. HTHARAC.
SMART	SM00342. HTH_ARAC. 1 hit. [Graphical view]
PROSITE	PS00041. HTH_ARAC_FAMILY_1. 1 hit. PS01124. HTH_ARAC_FAMILY_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADIY_ECOLI

Accession

Primary (citable) accession number: P33234
Secondary accession number(s): Q2M6I8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	February 1, 1994
Last modified:	November 24, 2009
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)