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P33207 (FABG_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 118. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic
EC=1.1.1.100
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase
Gene names
Ordered Locus Names:At1g24360
ORF Names:F21J9.2, F3I6.30
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathway

Lipid metabolism; fatty acid biosynthesis.

Subunit structure

Homotetramer Probable.

Subcellular location

Plastid › chloroplast. Plastid. Note: And non-photosynthetic plastids.

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Sequence caution

The sequence AAC00590.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence AAF97951.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 5959Chloroplast By similarity
Chain60 – 3192603-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic
PRO_0000031976

Regions

Nucleotide binding81 – 10525NADP By similarity

Sites

Active site2261Proton acceptor By similarity
Binding site2131Substrate By similarity

Experimental info

Sequence conflict171A → G in CAA45794. Ref.1
Sequence conflict227 – 2293AAA → TAT in CAA45794. Ref.1
Sequence conflict238 – 2403KTA → ETP in CAA45794. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P33207 [UniParc].

Last modified January 10, 2003. Version 2.
Checksum: 755ADDD16F3F69DE

FASTA31933,548
        10         20         30         40         50         60 
MAAAVAAPRL ISLKAVAKLG FREISQIRQL APLHSAIPHF GMLRCRSRQP FSTSVVKAQA 

        70         80         90        100        110        120 
TATEQSPGEV VQKVESPVVV ITGASRGIGK AIALALGKAG CKVLVNYARS AKEAEEVAKQ 

       130        140        150        160        170        180 
IEEYGGQAIT FGGDVSKATD VDAMMKTALD KWGTIDVVVN NAGITRDTLL IRMKQSQWDE 

       190        200        210        220        230        240 
VIALNLTGVF LCTQAAVKIM MKKKRGRIIN ISSVVGLIGN IGQANYAAAK GGVISFSKTA 

       250        260        270        280        290        300 
AREGASRNIN VNVVCPGFIA SDMTAELGED MEKKILGTIP LGRYGKAEEV AGLVEFLALS 

       310 
PAASYITGQA FTIDGGIAI

« Hide

References

« Hide 'large scale' references
[1]"Molecular cloning of higher-plant 3-oxoacyl-(acyl carrier protein) reductase. Sequence identities with the nodG-gene product of the nitrogen-fixing soil bacterium Rhizobium meliloti."
Slabas A.R., Chase D., Nishida I., Murata N., Sidebottom C.M., Safford R., Sheldon P.S., Kekwick R.G.O., Hardie D.G., Mackintosh R.W.
Biochem. J. 283:321-326(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Leaf.
[2]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X64464 mRNA. Translation: CAA45794.1.
AC000103 Genomic DNA. Translation: AAF97951.1. Sequence problems.
AC002396 Genomic DNA. Translation: AAC00590.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE30522.1.
AF324985 mRNA. Translation: AAG40337.1.
AY059816 mRNA. Translation: AAL24298.1.
AY081491 mRNA. Translation: AAM10053.1.
IPIIPI00543619.
PIRA86378.
S22416.
T00667.
RefSeqNP_564216.1. NM_102282.3.
UniGeneAt.4.
At.67665.

3D structure databases

ProteinModelPortalP33207.
SMRP33207. Positions 76-319.
ModBaseSearch...

Protein-protein interaction databases

STRING3702.AT1G24360.1-P.

Proteomic databases

PaxDbP33207.
PRIDEP33207.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G24360.1; AT1G24360.1; AT1G24360.
GeneID839053.
KEGGath:AT1G24360.

Organism-specific databases

TAIRAt1g24360.

Phylogenomic databases

eggNOGCOG1028.
InParanoidP33207.
KOK00059.
OMAMSKAVMR.
PhylomeDBP33207.
ProtClustDBCLSN2718402.

Enzyme and pathway databases

BioCycMetaCyc:AT1G24360-MONOMER.
UniPathwayUPA00094.

Gene expression databases

GenevestigatorP33207.
GermOnlineAT1G24360. Arabidopsis thaliana.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFABG_ARATH
AccessionPrimary (citable) accession number: P33207
Secondary accession number(s): O04463, Q9FPJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 10, 2003
Last modified: May 1, 2013
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents