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P33207

- FABG_ARATH

UniProt

P33207 - FABG_ARATH

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Protein

3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic

Gene
At1g24360, F21J9.2, F3I6.30
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei213 – 2131Substrate By similarity
Active sitei226 – 2261Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi81 – 10525NADP By similarityAdd
BLAST

GO - Molecular functioni

  1. 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Source: TAIR
  2. copper ion binding Source: TAIR
  3. NAD binding Source: InterPro

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciARA:AT1G24360-MONOMER.
MetaCyc:AT1G24360-MONOMER.
UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC:1.1.1.100)
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase
Gene namesi
Ordered Locus Names:At1g24360
ORF Names:F21J9.2, F3I6.30
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G24360.

Subcellular locationi

Plastidchloroplast. Plastid
Note: And non-photosynthetic plastids.

GO - Cellular componenti

  1. chloroplast Source: TAIR
  2. chloroplast envelope Source: TAIR
  3. chloroplast stroma Source: TAIR
  4. plastid Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 5959Chloroplast By similarityAdd
BLAST
Chaini60 – 3192603-oxoacyl-[acyl-carrier-protein] reductase, chloroplasticPRO_0000031976Add
BLAST

Proteomic databases

PaxDbiP33207.
PRIDEiP33207.

Expressioni

Gene expression databases

GenevestigatoriP33207.

Interactioni

Subunit structurei

Homotetramer Inferred.

Protein-protein interaction databases

STRINGi3702.AT1G24360.1-P.

Structurei

3D structure databases

ProteinModelPortaliP33207.
SMRiP33207. Positions 23-319.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG1028.
InParanoidiP33207.
KOiK00059.
OMAiEASKLMT.
PhylomeDBiP33207.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsiTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33207-1 [UniParc]FASTAAdd to Basket

« Hide

MAAAVAAPRL ISLKAVAKLG FREISQIRQL APLHSAIPHF GMLRCRSRQP    50
FSTSVVKAQA TATEQSPGEV VQKVESPVVV ITGASRGIGK AIALALGKAG 100
CKVLVNYARS AKEAEEVAKQ IEEYGGQAIT FGGDVSKATD VDAMMKTALD 150
KWGTIDVVVN NAGITRDTLL IRMKQSQWDE VIALNLTGVF LCTQAAVKIM 200
MKKKRGRIIN ISSVVGLIGN IGQANYAAAK GGVISFSKTA AREGASRNIN 250
VNVVCPGFIA SDMTAELGED MEKKILGTIP LGRYGKAEEV AGLVEFLALS 300
PAASYITGQA FTIDGGIAI 319
Length:319
Mass (Da):33,548
Last modified:January 10, 2003 - v2
Checksum:i755ADDD16F3F69DE
GO

Sequence cautioni

The sequence AAC00590.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence AAF97951.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti17 – 171A → G in CAA45794. 1 Publication
Sequence conflicti227 – 2293AAA → TAT in CAA45794. 1 Publication
Sequence conflicti238 – 2403KTA → ETP in CAA45794. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X64464 mRNA. Translation: CAA45794.1.
AC000103 Genomic DNA. Translation: AAF97951.1. Sequence problems.
AC002396 Genomic DNA. Translation: AAC00590.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE30522.1.
AF324985 mRNA. Translation: AAG40337.1.
AY059816 mRNA. Translation: AAL24298.1.
AY081491 mRNA. Translation: AAM10053.1.
PIRiA86378.
S22416.
T00667.
RefSeqiNP_564216.1. NM_102282.3.
UniGeneiAt.4.
At.67665.

Genome annotation databases

EnsemblPlantsiAT1G24360.1; AT1G24360.1; AT1G24360.
GeneIDi839053.
KEGGiath:AT1G24360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X64464 mRNA. Translation: CAA45794.1 .
AC000103 Genomic DNA. Translation: AAF97951.1 . Sequence problems.
AC002396 Genomic DNA. Translation: AAC00590.1 . Sequence problems.
CP002684 Genomic DNA. Translation: AEE30522.1 .
AF324985 mRNA. Translation: AAG40337.1 .
AY059816 mRNA. Translation: AAL24298.1 .
AY081491 mRNA. Translation: AAM10053.1 .
PIRi A86378.
S22416.
T00667.
RefSeqi NP_564216.1. NM_102282.3.
UniGenei At.4.
At.67665.

3D structure databases

ProteinModelPortali P33207.
SMRi P33207. Positions 23-319.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT1G24360.1-P.

Proteomic databases

PaxDbi P33207.
PRIDEi P33207.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G24360.1 ; AT1G24360.1 ; AT1G24360 .
GeneIDi 839053.
KEGGi ath:AT1G24360.

Organism-specific databases

TAIRi AT1G24360.

Phylogenomic databases

eggNOGi COG1028.
InParanoidi P33207.
KOi K00059.
OMAi EASKLMT.
PhylomeDBi P33207.

Enzyme and pathway databases

UniPathwayi UPA00094 .
BioCyci ARA:AT1G24360-MONOMER.
MetaCyc:AT1G24360-MONOMER.

Miscellaneous databases

PROi P33207.

Gene expression databases

Genevestigatori P33207.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view ]
Pfami PF00106. adh_short. 1 hit.
[Graphical view ]
PIRSFi PIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSi PR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsi TIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEi PS00061. ADH_SHORT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of higher-plant 3-oxoacyl-(acyl carrier protein) reductase. Sequence identities with the nodG-gene product of the nitrogen-fixing soil bacterium Rhizobium meliloti."
    Slabas A.R., Chase D., Nishida I., Murata N., Sidebottom C.M., Safford R., Sheldon P.S., Kekwick R.G.O., Hardie D.G., Mackintosh R.W.
    Biochem. J. 283:321-326(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Leaf.
  2. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.

Entry informationi

Entry nameiFABG_ARATH
AccessioniPrimary (citable) accession number: P33207
Secondary accession number(s): O04463, Q9FPJ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: January 10, 2003
Last modified: June 11, 2014
This is version 127 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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