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P33201 (MRT4_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
mRNA turnover protein 4
Gene names
Name:MRT4
Ordered Locus Names:YKL009W
ORF Names:YKL160
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length236 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in mRNA turnover and ribosome assembly.

Subcellular location

Nucleusnucleolus Ref.6.

Miscellaneous

Present with 18200 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ribosomal protein L10P family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 236236mRNA turnover protein 4
PRO_0000154815

Sequences

Sequence LengthMass (Da)Tools
P33201 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 9FCFDEE9F009F427

FASTA23627,058
        10         20         30         40         50         60 
MPRSKRSKLV TLAQTDKKGR ENKERIFDEV REALDTYRYV WVLHLDDVRT PVLQEIRTSW 

        70         80         90        100        110        120 
AGSKLIMGKR KVLQKALGEK REEEYKENLY QLSKLCSGVT GLLFTDEDVN TVKEYFKSYV 

       130        140        150        160        170        180 
RSDYSRPNTK APLTFTIPEG IVYSRGGQIP AEEDVPMIHS LEPTMRNKFE IPTKIKAGKI 

       190        200        210        220        230 
TIDSPYLVCT EGEKLDVRQA LILKQFGIAA SEFKVKVSAY YDNDSSTVES TNINME 

« Hide

References

« Hide 'large scale' references
[1]"The sequence of a 9.3 kb segment located on the left arm of the yeast chromosome XI reveals five open reading frames including the CCE1 gene and putative products related to MYO2 and to the ribosomal protein L10."
Pascolo S., Ghazvini M., Boyer J., Colleaux L., Thierry A., Dujon B.
Yeast 8:987-995(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete DNA sequence of yeast chromosome XI."
Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., Daignan-Fornier B., del Rey F., Dion C. expand/collapse author list , Domdey H., Duesterhoeft A., Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., Becker I., Mewes H.-W.
Nature 369:371-378(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Sequence of a 7.8 kb segment on the left arm of yeast chromosome XI reveals four open reading frames, including the CAP1 gene, an intron-containing gene and a gene encoding a homolog to the mammalian UOG-1 gene."
Boyer J., Pascolo S., Richard G.-F., Dujon B.
Yeast 9:279-287(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 190-236.
[5]"Temperature-sensitive mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 genes result in defects in mRNA turnover."
Zuk D., Belk J.P., Jacobson A.
Genetics 153:35-47(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE NAME, INVOLVEMENT IN MRNA TURNOVER.
[6]"Composition and functional characterization of yeast 66S ribosome assembly intermediates."
Harnpicharnchai P., Jakovljevic J., Horsey E., Miles T., Roman J., Rout M., Meagher D., Imai B., Guo Y., Brame C.J., Shabanowitz J., Hunt D.F., Woolford J.L. Jr.
Mol. Cell 8:505-515(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION, INVOLVEMENT IN RIBOSOME BIOGENESIS.
[7]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[8]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S53418 Genomic DNA. Translation: AAB24904.1.
X61398 Genomic DNA. No translation available.
Z28009 Genomic DNA. Translation: CAA81844.1.
S59773 Genomic DNA. Translation: AAC60552.1.
BK006944 Genomic DNA. Translation: DAA09147.1.
PIRS30013.
RefSeqNP_012916.1. NM_001179575.1.

3D structure databases

ProteinModelPortalP33201.
SMRP33201. Positions 20-225.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34123. 226 interactions.
DIPDIP-5283N.
IntActP33201. 19 interactions.
MINTMINT-8285311.
STRING4932.YKL009W.

Proteomic databases

PaxDbP33201.
PeptideAtlasP33201.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYKL009W; YKL009W; YKL009W.
GeneID853860.
KEGGsce:YKL009W.

Organism-specific databases

CYGDYKL009w.
SGDS000001492. MRT4.

Phylogenomic databases

eggNOGCOG0244.
GeneTreeENSGT00390000006238.
HOGENOMHOG000177263.
KOK14815.
OMAKTKVMAK.
OrthoDBEOG7RJQ36.

Enzyme and pathway databases

BioCycYEAST:G3O-31818-MONOMER.

Gene expression databases

GenevestigatorP33201.

Family and domain databases

InterProIPR001790. Ribosomal_L10/acidic_P0.
[Graphical view]
PfamPF00466. Ribosomal_L10. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio975109.
PROP33201.

Entry information

Entry nameMRT4_YEAST
AccessionPrimary (citable) accession number: P33201
Secondary accession number(s): D6VXS7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: April 16, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XI

Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries