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P33129 (HTRE_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 120. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Outer membrane usher protein HtrE
Alternative name(s):
Heat shock protein E
Gene names
Name:htrE
Ordered Locus Names:b0139, JW0135
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length865 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Probable porin-like protein necessary for the assembly of a pilin-type protein.

Subcellular location

Cell outer membrane; Multi-pass membrane protein By similarity.

Induction

By heat shock.

Sequence similarities

Belongs to the fimbrial export usher family.

Sequence caution

The sequence AAA23721.1 differs from that shown. Reason: Incorrect in position 61 onward due to a cloning artifact.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2929 Ref.5
Chain30 – 865836Outer membrane usher protein HtrE
PRO_0000009319

Amino acid modifications

Disulfide bond838 ↔ 862 Potential

Experimental info

Sequence conflict511S → T in AAA23721. Ref.1
Sequence conflict810 – 8112QG → HR in AAA23721. Ref.1
Sequence conflict8491E → P in AAA23721. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P33129 [UniParc].

Last modified November 1, 1997. Version 3.
Checksum: F1748B551E4A5AAE

FASTA86595,499
        10         20         30         40         50         60 
MTIEYTKNYH HLTRIATFCA LLYCNTAFSA ELVEYDHTFL MGQNASNIDL SRYSEGNPAI 

        70         80         90        100        110        120 
PGVYDVSVYV NDQPIINQSI TFVAIEGKKN AQACITLKNL LQFHINSPDI NNEKAVLLAR 

       130        140        150        160        170        180 
DETLGNCLNL TEIIPQASVR YDVNDQRLDI DVPQAWVMKN YQNYVDPSLW ENGINAAMLS 

       190        200        210        220        230        240 
YNLNGYHSET PGRKNESIYA AFNGGMNLGA WRLRASGNYN WMTDSGSNYD FKNRYVQRDI 

       250        260        270        280        290        300 
ASLRSQLILG ESYTTGETFD SVSIRGIRLY SDSRMLPPTL ASFAPIIHGV ANTNAKVTIT 

       310        320        330        340        350        360 
QGGYKIYETT VPPGAFVIDD LSPSGYGSDL IVTIEESDGS KRTFSQPFSS VVQMLRPGVG 

       370        380        390        400        410        420 
RWDISGGQVL KDDIQDEPNL FQASYYYGLN NYLTGYTGIQ ITDNNYTAGL LGLGLNTSVG 

       430        440        450        460        470        480 
AFSFDVTHSN VRIPDDKTYQ GQSYRVSWNK LFEETSTSLN IAAYRYSTQN YLGLNDALTL 

       490        500        510        520        530        540 
IDEVKHPEQD LEPKSMRNYS RMKNQVTVSI NQPLKFEKKD YGSFYLSGSW SDYWASGQNR 

       550        560        570        580        590        600 
SNYSIGYSNS TSWGSYSVSA QRSWNEDGDT DDSVYLSFTI PIEKLLGTEQ RTSGFQSIDT 

       610        620        630        640        650        660 
QISSDFKGNN QLNVSSSGYS DNARVSYSVN TGYTMNKASK DLSYVGGYAS YESPWGTLAG 

       670        680        690        700        710        720 
SISANSDNSR QVSLSTDGGF VLHSGGLTFS NDSFSDSDTL AVVQAPGAQG ARINYGNSTI 

       730        740        750        760        770        780 
DRWGYGVTSA LSPYHENRIA LDINDLENDV ELKSTSAVAV PRQGSVVFAD FETVQGQSAI 

       790        800        810        820        830        840 
MNITRSDGKN IPFAADIYDE QGNVIGNVGQ GGQAFVRGIE QQGNISIKWL EQSKPVSCLA 

       850        860 
HYQQSPEAEK IAQSIILNGI RCQIQ 

« Hide

References

« Hide 'large scale' references
[1]"Identification and transcriptional analysis of the Escherichia coli htrE operon which is homologous to pap and related pilin operons."
Raina S., Missiakas D., Baird L., Kumar S., Georgopoulos C.
J. Bacteriol. 175:5009-5021(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K12.
[2]"Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region."
Fujita N., Mori H., Yura T., Ishihama A.
Nucleic Acids Res. 22:1637-1639(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]Raina S.
Submitted (DEC-1994) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 30-33.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L00680 Genomic DNA. Translation: AAA23721.1. Sequence problems.
U00096 Genomic DNA. Translation: AAC73250.1.
AP009048 Genomic DNA. Translation: BAE76043.1.
PIRC64737.
RefSeqNP_414681.1. NC_000913.3.
YP_488442.1. NC_007779.1.

3D structure databases

ProteinModelPortalP33129.
SMRP33129. Positions 32-850.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-9953N.
IntActP33129. 9 interactions.
MINTMINT-1300601.
STRING511145.b0139.

Protein family/group databases

TCDB1.B.11.3.3. the outer membrane fimbrial usher porin (fup) family.

Proteomic databases

PaxDbP33129.
PRIDEP33129.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC73250; AAC73250; b0139.
BAE76043; BAE76043; BAE76043.
GeneID12930744.
944819.
KEGGecj:Y75_p0136.
eco:b0139.
PATRIC32115385. VBIEscCol129921_0144.

Organism-specific databases

EchoBASEEB1915.
EcoGeneEG11972. htrE.

Phylogenomic databases

eggNOGCOG3188.
HOGENOMHOG000111416.
KOK07347.
OMAYVQRDIT.
OrthoDBEOG6GJBP9.
PhylomeDBP33129.
ProtClustDBPRK09828.

Enzyme and pathway databases

BioCycEcoCyc:EG11972-MONOMER.
ECOL316407:JW0135-MONOMER.

Gene expression databases

GenevestigatorP33129.

Family and domain databases

InterProIPR000015. Fimb_usher.
IPR018030. Fimbrial_membr_usher_CS.
IPR025949. PapC-like_C.
IPR025885. PapC_N_dom.
[Graphical view]
PfamPF13953. PapC_C. 1 hit.
PF13954. PapC_N. 1 hit.
PF00577. Usher. 1 hit.
[Graphical view]
PROSITEPS01151. FIMBRIAL_USHER. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP33129.

Entry information

Entry nameHTRE_ECOLI
AccessionPrimary (citable) accession number: P33129
Secondary accession number(s): Q2MCG3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene