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Protein

Probable fimbrial chaperone YadV

Gene

yadV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Fimbrium biogenesis, Stress response

Enzyme and pathway databases

BioCyciEcoCyc:EG11973-MONOMER.
ECOL316407:JW0136-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable fimbrial chaperone YadV
Gene namesi
Name:yadV
Synonyms:ecpD
Ordered Locus Names:b0140, JW0136
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11973. yadV.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

Pathology & Biotechi

Disruption phenotypei

Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000000926926 – 246Probable fimbrial chaperone YadVAdd BLAST221

Proteomic databases

PaxDbiP33128.
PRIDEiP33128.

Expressioni

Inductioni

Repressed by H-NS. Induced by heat shock.2 Publications

Interactioni

Protein-protein interaction databases

BioGridi4263031. 16 interactors.
DIPiDIP-9492N.
IntActiP33128. 1 interactor.
MINTiMINT-1302192.
STRINGi511145.b0140.

Structurei

3D structure databases

ProteinModelPortaliP33128.
SMRiP33128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the periplasmic pilus chaperone family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiENOG4108VEV. Bacteria.
ENOG4111JH1. LUCA.
HOGENOMiHOG000260152.
InParanoidiP33128.
KOiK15540.
OMAiDQKSVSV.
PhylomeDBiP33128.

Family and domain databases

Gene3Di2.60.40.1070. 1 hit.
2.60.40.360. 1 hit.
InterProiIPR008962. PapD-like.
IPR001829. Pili_assmbl_chaperone_bac.
IPR016148. Pili_assmbl_chaperone_C.
IPR018046. Pili_assmbl_chaperone_CS.
IPR016147. Pili_assmbl_chaperone_N.
[Graphical view]
PfamiPF02753. PapD_C. 1 hit.
PF00345. PapD_N. 1 hit.
[Graphical view]
PRINTSiPR00969. CHAPERONPILI.
SUPFAMiSSF49354. SSF49354. 1 hit.
SSF49584. SSF49584. 1 hit.
PROSITEiPS00635. PILI_CHAPERONE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P33128-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFNTKHTTA LCFVTCMAFS SSSIADIVIS GTRVIYKSDQ KSVNVRLENK
60 70 80 90 100
GNNPLLVQSW LDTGDDNAEP GSITVPFTAT PPVSRIDAKR GQTIKLMYTA
110 120 130 140 150
STSLPKDRES VFWFNVLEVP PKPDAEKVAN QSLLQLAFRT RIKLFYRPDG
160 170 180 190 200
LKGNPSEAPL ALKWFWSGSE GKASLRVTNP TPYYVSFSSG DLEASGKRYP
210 220 230 240
IDVKMIAPFS DEVMKVNGLN GKANSAKVHF YAINDFGGAI EGNARL
Length:246
Mass (Da):27,054
Last modified:November 1, 1997 - v2
Checksum:i33C77D484DD77E08
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti79A → R in AAA23720 (PubMed:8102362).Curated1
Sequence conflicti110 – 111SV → RA in AAA23720 (PubMed:8102362).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L00680 Genomic DNA. Translation: AAA23720.1.
U00096 Genomic DNA. Translation: AAC73251.1.
AP009048 Genomic DNA. Translation: BAB96716.1.
PIRiS45209.
RefSeqiNP_414682.1. NC_000913.3.
WP_000465928.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73251; AAC73251; b0140.
BAB96716; BAB96716; BAB96716.
GeneIDi944859.
KEGGiecj:JW0136.
eco:b0140.
PATRICi32115387. VBIEscCol129921_0145.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L00680 Genomic DNA. Translation: AAA23720.1.
U00096 Genomic DNA. Translation: AAC73251.1.
AP009048 Genomic DNA. Translation: BAB96716.1.
PIRiS45209.
RefSeqiNP_414682.1. NC_000913.3.
WP_000465928.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP33128.
SMRiP33128.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263031. 16 interactors.
DIPiDIP-9492N.
IntActiP33128. 1 interactor.
MINTiMINT-1302192.
STRINGi511145.b0140.

Proteomic databases

PaxDbiP33128.
PRIDEiP33128.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73251; AAC73251; b0140.
BAB96716; BAB96716; BAB96716.
GeneIDi944859.
KEGGiecj:JW0136.
eco:b0140.
PATRICi32115387. VBIEscCol129921_0145.

Organism-specific databases

EchoBASEiEB1916.
EcoGeneiEG11973. yadV.

Phylogenomic databases

eggNOGiENOG4108VEV. Bacteria.
ENOG4111JH1. LUCA.
HOGENOMiHOG000260152.
InParanoidiP33128.
KOiK15540.
OMAiDQKSVSV.
PhylomeDBiP33128.

Enzyme and pathway databases

BioCyciEcoCyc:EG11973-MONOMER.
ECOL316407:JW0136-MONOMER.

Miscellaneous databases

PROiP33128.

Family and domain databases

Gene3Di2.60.40.1070. 1 hit.
2.60.40.360. 1 hit.
InterProiIPR008962. PapD-like.
IPR001829. Pili_assmbl_chaperone_bac.
IPR016148. Pili_assmbl_chaperone_C.
IPR018046. Pili_assmbl_chaperone_CS.
IPR016147. Pili_assmbl_chaperone_N.
[Graphical view]
PfamiPF02753. PapD_C. 1 hit.
PF00345. PapD_N. 1 hit.
[Graphical view]
PRINTSiPR00969. CHAPERONPILI.
SUPFAMiSSF49354. SSF49354. 1 hit.
SSF49584. SSF49584. 1 hit.
PROSITEiPS00635. PILI_CHAPERONE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYADV_ECOLI
AccessioniPrimary (citable) accession number: P33128
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 133 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed.1 Publication

Caution

Was originally called ecpD, but ecp is now used for the ecpABCDE operon involved in E.coli common pilus (ECP) synthesis.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.