P33030 (YEIR_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YeiR

Gene names

Name:	yeiR
Ordered Locus Names:	b2173, JW2161

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the CobW family. Contains 1 cobW C-terminal domain.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	GTPase activity Inferred from direct assay PubMed 22511334. Source: EcoCyc zinc ion binding Inferred from direct assay PubMed 22511334. Source: EcoCyc
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	Uncharacterized protein YeiR		PRO_0000169151
Regions
	Domain	240 – 323	84	CobW C-terminal
Experimental info
	Sequence conflict	103 – 105	3	DLL → LSF in AAA60521. Ref.4
	Sequence conflict	285 – 328	44	GDDLH…LATTA → AMTCTLKRKTLRHRTAVLS Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P33030 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 83C542DE4E0B4DA6	FASTA	328	36,113
	10 20 30 40 50 60 MTRTNLITGF LGSGKTTSIL HLLAHKDPNE KWAVLVNEFG EVGIDGALLA DSGALLKEIP 70 80 90 100 110 120 GGCMCCVNGL PMQVGLNTLL RQGKPDRLLI EPTGLGHPKQ ILDLLTAPVY EPWIDLRATL 130 140 150 160 170 180 CILDPRLLLD EKSASNENFR DQLAAADIIV ANKSDRTTPE SEQALQRWWQ QNGGDRQLIH 190 200 210 220 230 240 SEHGKVDGHL LDLPRRNLAE LPASAAHSHQ HVVKKGLAAL SLPEHQRWRR SLNSGQGYQA 250 260 270 280 290 300 CGWIFDADTV FDTIGILEWA RLAPVERVKG VLRIPEGLVR INRQGDDLHI ETQNVAPPDS 310 320 RIELISSSEA DWNALQSALL KLRLATTA

References

[1]	"A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map." Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S. , Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:379-392(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO 285-328. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Automated multiplex sequencing of the E.coli genome." Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K., Church G.M. Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-105. Strain: K12 / BHB2600.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC75234.1. AP009048 Genomic DNA. Translation: BAA15982.2. U00007 Genomic DNA. Translation: AAA60521.2.
PIR	D64986.
RefSeq	NP_416678.1. NC_000913.2. YP_490413.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P33030.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-11929N.
IntAct	P33030. 7 interactions.
MINT	MINT-1231253.
STRING	511145.b2173.
Proteomic databases
PaxDb	P33030.
PRIDE	P33030.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC75234; AAC75234; b2173. BAA15982; BAA15982; BAA15982.
GeneID	12931474. 946701.
KEGG	ecj:Y75_p2136. eco:b2173.
PATRIC	32119701. VBIEscCol129921_2261.
Organism-specific databases
EchoBASE	EB2028.
EcoGene	EG12104. yeiR.
Phylogenomic databases
eggNOG	COG0523.
HOGENOM	HOG000294929.
OMA	KGVMRIK.
ProtClustDB	CLSK880319.
Enzyme and pathway databases
BioCyc	EcoCyc:EG12104-MONOMER. ECOL316407:JW2161-MONOMER. MetaCyc:EG12104-MONOMER.
Gene expression databases
Genevestigator	P33030.
Family and domain databases
InterPro	IPR011629. Cbl_biosynth_CobW-like_C. IPR003495. CobW/HypB/UreG_dom. [Graphical view]
Pfam	PF02492. cobW. 1 hit. PF07683. CobW_C. 1 hit. [Graphical view]
SMART	SM00833. CobW_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YEIR_ECOLI

Accession

Primary (citable) accession number: P33030
Secondary accession number(s): P76444, P94761

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1994
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 105 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program