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Protein

Probable alcohol dehydrogenase

Gene

terPD

Organism
Pseudomonas sp.
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

An alcohol + NAD+ = an aldehyde or ketone + NADH.

Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi18Zinc 1; catalyticBy similarity1
Metal bindingi39Zinc 1; catalyticBy similarity1
Metal bindingi68Zinc 2By similarity1
Metal bindingi71Zinc 2By similarity1
Metal bindingi74Zinc 2By similarity1
Metal bindingi82Zinc 2By similarity1
Metal bindingi149Zinc 1; catalyticBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, NAD, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alcohol dehydrogenase (EC:1.1.1.1)
Gene namesi
Name:terPD
OrganismiPseudomonas sp.
Taxonomic identifieri306 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001607511 – 319Probable alcohol dehydrogenaseAdd BLAST319

Structurei

3D structure databases

ProteinModelPortaliP33010.
SMRiP33010.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiView protein in InterPro
IPR013149. ADH_C.
IPR013154. ADH_N.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
PfamiView protein in Pfam
PF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00059. ADH_ZINC. 1 hit.

Sequencei

Sequence statusi: Complete.

P33010-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRREMMKCL FVSESCVCHT DLAIKDGVLP FPLPAVLGHE GSGIVEAVGP
60 70 80 90 100
GVKHLKPGDA VVMTFASCGH CASCEHERPS YCLDFGAQNY SAQRADGPVL
110 120 130 140 150
LSQGDEVISG FFFGQSSFSS MAMAREHNLV KIDALVDDAP IELLGPLGCG
160 170 180 190 200
VQTGAGAVMI SLDVRAGRSF LVLGGGAVGL SAVMAAKLRG CSRIIVSEPS
210 220 230 240 250
AAKREQALAL GATEVIDPLN ENLVERVQQI TEGQGCDYAL ECTGLVSVME
260 270 280 290 300
QAIDSMAMRG QLAVVGVPPK LDATAAVSPL ALIQKGLKLM GVIEGDSCRV
310
YSSTSCTRSS RLGVFRSPR
Length:319
Mass (Da):33,401
Last modified:October 1, 1993 - v1
Checksum:i0478906D3C21A614
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91440 Genomic DNA. Translation: AAA25994.1.
PIRiB42971.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91440 Genomic DNA. Translation: AAA25994.1.
PIRiB42971.

3D structure databases

ProteinModelPortaliP33010.
SMRiP33010.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiView protein in InterPro
IPR013149. ADH_C.
IPR013154. ADH_N.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
PfamiView protein in Pfam
PF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00059. ADH_ZINC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTERPD_PSESP
AccessioniPrimary (citable) accession number: P33010
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: February 15, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.