P33008 (ALDH_PSESP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable aldehyde dehydrogenase
EC=1.2.1.3

Gene names

Name:

terPE

Organism

Pseudomonas sp.

Taxonomic identifier

306 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › unclassified Proteobacteria › unclassified pseudomonads

Protein attributes

Sequence length	488 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in an alpha-terpineol oxidation system.
Catalytic activity	An aldehyde + NAD+ + H2O = a carboxylate + NADH.
Sequence similarities	Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Gene Ontology (GO)
Molecular_function	aldehyde dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 488	488	Probable aldehyde dehydrogenase		PRO_0000056452
Regions
	Nucleotide binding	240 – 245	6	NAD By similarity
Sites
	Active site	262	1	By similarity
	Active site	296	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P33008 [UniParc]. Last modified October 1, 1993. Version 1. Checksum: 2144AE1EB173C854	FASTA	488	52,156
	10 20 30 40 50 60 MSSRESASRR PDPLRVTIMQ SPSAFSLTIG GHGVATSDYL PVLNPATRQP IGQCPVASEE 70 80 90 100 110 120 HVEQARAAAG DAFAVWRQVP YGKRCEQLQA LAGILEAHLD ELAQLLTHEQ GKPLADARGE 130 140 150 160 170 180 LAGAIAFCQC AGSLPLPEVV HEQSATRLSK TVREPLGVVV AIVPWNYPVS IAFVKPDRRV 190 200 210 220 230 240 GCRKHADSQA GADHAADYLR IGELIRDALP AGVINVLAGN DDLGPWLTGH ADVAKISFTG 250 260 270 280 290 300 SSVTGRHVAR SAAADLKRLT LELGGNDAAV VMADSLSDAV VERVFWSAFT NAGQICMATK 310 320 330 340 350 360 RLYIHESIYE AFRDKLVAYA QNVVIGDGSQ PGVTMGPLQN AKQFAKVMSL IDAVRQRGGR 370 380 390 400 410 420 LIECGQMRGG DGYFLPITFV DLPDESAPEV VEEAFGPLLP LLKFRDVDEV IERVNAARTG 430 440 450 460 470 480 WLAASGVVIG RSAHGLQQPS TRSVWSTTGC DHAVYSFGGM KASGYGAESG LEGLLEFTTQ KTVIIQQQ

References

[1]

"Cytochrome P-450terp. Isolation and purification of the protein and cloning and sequencing of its operon." Peterson J.A., Lu J.-Y., Geisselsoder J., Graham-Lorence S., Carmona C., Witney F., Lorence M.C. J. Biol. Chem. 267:14193-14203(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M91440 Genomic DNA. Translation: AAA25995.1.
PIR	S27652. C42971.
3D structure databases
ProteinModelPortal	P33008.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.40.309.10. 1 hit. 3.40.605.10. 1 hit.
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. [Graphical view]
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALDH_PSESP

Accession

Primary (citable) accession number: P33008

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1993
Last sequence update:	October 1, 1993
Last modified:	April 3, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program